Xilia Trio 2

XILIA TRIO 2 by EMCURE PHARMACEUTICALS LTD

XILIA TRIO 2 (also known as XILIA TRIO 2MG TABLET or Xilia Trio 2 Tablet SR) is an anti-diabetic medication manufactured by Emcure Pharmaceuticals Ltd.

• Composition: Each tablet contains a combination of three active ingredients: Glimepiride (2mg), Metformin (500mg), and Voglibose (0.2mg).

• Uses: This medicine is prescribed for adults to manage Type 2 Diabetes Mellitus. It is typically used when diet, exercise, and single-agent or dual therapy are insufficient to adequately control blood sugar levels. XILIA TRIO 2 works by stimulating insulin release, reducing glucose production in the liver, and delaying carbohydrate absorption from the intestines, thereby helping to maintain optimal blood glucose levels and prevent diabetes complications.

• Dosage and Administration: XILIA TRIO 2 should be taken orally as advised by your physician, usually with food to prevent an upset stomach. It is recommended to swallow the tablet whole with a glass of water, without crushing, chewing, or splitting it. For optimal results, it should be taken at the same time each day. Do not adjust the dose or stop the medication without consulting a healthcare provider.

• Side Effects: Common side effects may include hypoglycemia (low blood sugar), taste changes, nausea, diarrhea, stomach pain, headache, and upper respiratory tract infections. Serious, though rare, side effects can include lactic acidosis (characterized by extreme fatigue, body weakness, diarrhea, and headache) and severe allergic reactions.

• Precautions: XILIA TRIO 2 is not recommended for patients with Type 1 diabetes, diabetic ketoacidosis, severe kidney or liver problems, or acute conditions like dehydration or severe infection. It is contraindicated in pregnant and breastfeeding women. Caution is advised when used in elderly patients or those with a history of heart disease. Alcohol consumption should be avoided as it can increase the risk of hypoglycemia and lactic acidosis. Inform your doctor about all existing medical conditions and current medications to avoid potential drug interactions.

• Storage: Store XILIA TRIO 2 tablets at room temperature, generally below 25°C or 30°C. Protect the medicine from light and moisture, and keep it out of reach of children.

Here are frequently asked questions about XILIA TRIO 2 by EMCURE PHARMACEUTICALS LTD:

What is XILIA TRIO 2 used for?

XILIA TRIO 2 is an anti-diabetic medicine primarily used to manage Type 2 Diabetes Mellitus in adults. It helps control high blood sugar levels and works to prevent serious long-term complications of diabetes such as kidney damage, eye damage, nerve problems, and reduced risk of heart attack or stroke.

How does XILIA TRIO 2 work?

XILIA TRIO 2 contains a combination of three active ingredients: Glimepiride, Metformin, and Voglibose.

• Glimepiride stimulates the pancreas to release more insulin.
• Metformin works by reducing glucose production in the liver, decreasing the absorption of glucose from the intestines, and improving the body's sensitivity to insulin.
• Voglibose slows down the breakdown and absorption of carbohydrates in the intestines, which helps prevent sharp rises in blood sugar levels after meals. These combined actions help maintain steady blood glucose levels.

What is the usual dosage of XILIA TRIO 2?

The dosage of XILIA TRIO 2 should be strictly as advised by your doctor. Typically, the usual dose is one tablet per day, preferably taken with meals to minimize gastrointestinal discomfort. The tablet should be swallowed whole with water and not crushed or chewed. Your doctor will determine the correct dosage based on your individual health needs and response to treatment.

What are the possible side effects of XILIA TRIO 2?

Common side effects include upper respiratory tract infection, diarrhea, nausea or vomiting, abdominal discomfort, dyspepsia (indigestion), headache, dizziness, altered taste, flatulence, and hypoglycemia (low blood sugar). It is important to recognize the signs of low blood glucose, such as sweating, dizziness, headache, and shaking. Less common but severe side effects can include lactic acidosis and severe allergic reactions. Consult your doctor if any side effects persist or worsen.

Is XILIA TRIO 2 safe during pregnancy or breastfeeding?

XILIA TRIO 2 is generally not recommended for use during pregnancy as it may cause harm to the developing fetus. Similarly, it is not recommended during breastfeeding because its components can pass into breast milk and potentially harm the nursing child. Always consult your doctor to discuss the potential risks and benefits if you are pregnant or breastfeeding, or planning to become pregnant.

Can XILIA TRIO 2 be taken with other medications?

XILIA TRIO 2 can interact with various other medications. Inform your doctor about all medicines you are currently taking, including prescribed, non-prescribed, herbal medicines, and dietary supplements. Some medications that may interact include:

• Cationic medicines like amiloride, digoxin, morphine, and ranitidine.
• Hyperglycemia-inducing medicines such as estrogens, phenytoin, and isoniazid.
• Blood thinners (e.g., phenprocoumon).
• Oral contraceptives, certain other anti-diabetic medications, and drugs for brain/heart disorders, tuberculosis, acidity, fungal infections, painkillers, and antihypertensive medicines. These interactions can affect the effectiveness of XILIA TRIO 2 or increase the risk of side effects.

What precautions should be taken while taking XILIA TRIO 2?

• Do not take XILIA TRIO 2 if you are allergic to any of its components.
• It is not suitable for individuals with Type 1 diabetes, diabetic ketoacidosis, or severe kidney or liver disease.
• Alcohol consumption should be avoided or limited, as it can intensify the effect on blood sugar levels and increase the risk of lactic acidosis.
• Regular monitoring of blood sugar levels is crucial.
• Always carry a fast-acting source of glucose (like sugary food or fruit juice) to manage potential low blood sugar (hypoglycemia).
• Inform your doctor if you have a history of heart disease, plan to undergo surgery, or certain diagnostic procedures involving contrast media (like CT scans or MRI).
• Do not stop taking XILIA TRIO 2 abruptly without consulting your doctor, as this can lead to an increase in blood sugar levels and a higher risk of complications.
• Long-term use may require monitoring of vitamin B12 levels.

What happens if a dose of XILIA TRIO 2 is missed?

If you miss a dose of XILIA TRIO 2, take it as soon as you remember, unless it is almost time for your next scheduled dose. Do not take two doses at once to make up for a missed dose.

How should XILIA TRIO 2 be stored?

XILIA TRIO 2 should be stored in a cool and dry place, away from direct sunlight, ideally below 30°C. Keep it out of the sight and reach of children.