Empagreat 10mg Tab

EMPAGREAT 10MG TABLET

Name

• Brand Name: EMPAGREAT 10MG TAB
• Common Name: Empagliflozin (active ingredient)

Composition

• Active Ingredient: Each tablet contains Empagliflozin 10 mg.

Uses

EMPAGREAT 10MG TAB is prescribed for the management of several medical conditions:

• Type 2 Diabetes Mellitus: It helps to lower blood sugar levels in adults and children (10 years and older) when used in conjunction with a healthy diet and exercise plan.
• Heart Failure: It reduces the risk of cardiovascular death and hospitalization in adults with heart failure.
• Chronic Kidney Disease: It helps to slow the progression of chronic kidney disease (CKD) and reduce the risk of kidney failure.

Dosage and Administration

• Typical Dosage: The usual starting dose for adults is one 10 mg tablet once daily, taken orally with or without food.
• Administration: It should be swallowed whole with water, preferably at the same time each day.
• Dosage Adjustment: Your doctor may increase the dose to 25 mg daily if better blood sugar control is needed and the starting dose is well-tolerulated.
• Important Note: Do not stop taking the medicine suddenly without consulting your doctor.

Side Effects

• Common Side Effects:
  • Urinary tract infections (UTIs)
  • Increased urination and thirst
  • Genital yeast infections (e.g., vaginal thrush in women, redness/itching in men)
  • Mild skin rash or itching
  • Constipation
  • Low blood sugar (hypoglycemia), particularly when taken with insulin or sulfonylureas.
• Serious Side Effects (Report to healthcare provider immediately):
  • Diabetic ketoacidosis (DKA), a dangerous buildup of acids in the blood, which can occur even with normal blood sugar levels.
  • Dehydration (symptoms include increased thirst, dizziness, fainting, lightheadedness, weakness, dark urine).
  • Severe urinary tract infections.
  • Necrotizing fasciitis (Fournier's gangrene), a severe bacterial infection in the genital area.
  • Allergic reactions (e.g., skin rash, itching, hives, swelling of face/lips/tongue/throat).
  • Acute kidney injury or worsening kidney problems.
  • Low blood pressure (hypotension).
  • Increased risk of lower limb amputation in some patients.

Precautions

• Diabetic Ketoacidosis (DKA): Be aware of symptoms like nausea, vomiting, stomach pain, or breathing problems, and seek emergency help if they occur.
• Dehydration: Drink plenty of fluids while taking this medicine.
• Infections: This medication can increase the risk of urinary tract infections and genital yeast infections. Maintain good personal hygiene.
• Alcohol Consumption: Avoid excessive alcohol, as it can increase the risk of DKA and dehydration.
• Pregnancy and Breastfeeding: Not recommended during pregnancy, especially in the second and third trimesters, or while breastfeeding, due to potential risks to the baby.
• Kidney/Liver Problems: Use with caution in patients with kidney or liver impairment; careful monitoring may be required.
• Other Medications: Inform your doctor about all other medications, supplements, or herbals you are taking, especially diuretics, insulin, or sulfonylureas, to avoid potential interactions and risks like hypoglycemia.
• Type 1 Diabetes: This medication is not for use in patients with Type 1 Diabetes.
• Surgery: If you plan to undergo surgery, inform your doctor, as temporary discontinuation may be advised.

Storage

• Store EMPAGREAT 10MG TAB at room temperature, between 68°F to 77°F (20°C to 25°C). Brief exposure between 59°F and 86°F (15°C and 30°C) is acceptable.
• Keep the medication in a tightly closed container, protected from moisture and light.
• Keep it out of the reach of children and pets.
• Do not use after the expiry date.

EMPAGREAT 10MG TAB by MANKIND PHARMA LTD.

Here are some frequently asked questions about EMPAGREAT 10MG TABLET:

What is EMPAGREAT 10MG TAB used for?

EMPAGREAT 10MG TAB is primarily used to manage Type 2 diabetes mellitus in adults and children when diet and exercise alone are not sufficient. It also helps protect against heart disease, treat heart failure in adults with reduced heart function, and slow the progression of chronic kidney disease.

How does EMPAGREAT 10MG TAB work?

EMPAGREAT 10MG TAB contains empagliflozin, which belongs to a class of drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors. It works by blocking the SGLT2 protein in the kidneys, which prevents the reabsorption of glucose back into the bloodstream. This leads to increased glucose excretion through urine, thereby lowering blood sugar levels. This process also contributes to mild salt and water loss, reducing the workload on the heart and protecting kidney function.

What is the usual dosage of EMPAGREAT 10MG TAB?

Adults typically start with a 10 mg pill once each morning, which can be taken with or without food. Your doctor may increase the dose to 25 mg daily if better blood sugar control is needed and the initial dose is well-tolerated. Children 10 years and older with Type 2 diabetes also begin with 10 mg daily, which may be increased to 25 mg if necessary. It is recommended to take it at the same time each day to maintain consistency.

What are the possible side effects of EMPAGREAT 10MG TAB?

Common side effects include urinary tract infections (UTIs), increased urination, increased thirst, and genital fungal infections (e.g., vaginal yeast infection). Other possible side effects can include low blood sugar (hypoglycemia), nausea, vomiting, constipation, and nasopharyngitis (inflammation of the throat and nasal passages).

Is EMPAGREAT 10MG TAB safe during pregnancy or breastfeeding?

EMPAGREAT 10MG TAB is probably unsafe to use during pregnancy, as limited studies in humans and animal studies have shown harmful effects on the developing baby. Similarly, it is probably unsafe to use during breastfeeding, as limited human data suggests the drug may pass into breast milk and harm the baby. Therefore, pregnant or breastfeeding women should consult their healthcare provider before use.

Can EMPAGREAT 10MG TAB be taken with other medications?

Yes, EMPAGREAT 10MG TAB can interact with other medicines. For example, taking it with diuretics (water pills) like furosemide may increase the risk of dehydration. When taken with other antidiabetic medications, such as insulin or sulfonylureas, it can increase the risk of low blood sugar, and dose adjustments may be required. It can also increase lithium levels when used concurrently. Always inform your doctor about all medicines, supplements, or herbs you are currently taking.

What precautions should be taken with EMPAGREAT 10MG TAB?

It is important to inform your doctor about any pre-existing kidney or liver conditions, urinary tract infections, or if you are taking diuretics. This medication can lead to dehydration due to increased urination, so ensure adequate fluid intake. Alcohol consumption should be limited during treatment as it can increase the risk of certain side effects and ketoacidosis. EMPAGREAT 10MG TAB is not recommended for people with Type 1 diabetes. Regular monitoring of blood sugar levels is essential.

What happens if a dose of EMPAGREAT 10MG TAB is missed?

If you miss a dose of EMPAGREAT 10MG TAB, take it as soon as you remember. However, if it is less than 12 hours until your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for a forgotten one.

How should EMPAGREAT 10MG TAB be stored?

EMPAGREAT 10MG TAB should be stored below 30°C in a cool, dry place.