Eplehef 25 Mg Tablet (10 Tab)

EPLEHEF 25 MG TABLET

EPLEHEF 25 MG TABLET is a prescription medicine manufactured by SUN PHARMA LABORATORIES LTD.

• Name:

  • Brand Name: EPLEHEF 25 MG TABLET
  • Common Name: Eplerenone (as 25 mg tablets)

• Composition:

  • Active Ingredient: Eplerenone 25 mg

• Uses: EPLEHEF 25 MG TABLET is primarily used for:

  • High Blood Pressure (Hypertension): It helps to lower elevated blood pressure, often prescribed alone or in combination with other antihypertensive medications.
  • Heart Failure: It is used in the management and treatment of heart failure, particularly in stable patients with left ventricular dysfunction and clinical evidence of congestive heart failure following a recent heart attack. It improves heart function and reduces the risk of hospitalization and death due to heart-related complications.
  • Edema (Swelling due to fluid retention): It aids in alleviating swelling resulting from various underlying conditions by helping the body remove excess water and salt through urine.

• Dosage and Administration:

  • Take EPLEHEF 25 MG TABLET exactly as prescribed by your doctor.
  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break it.
  • It can be taken with or without food, but consistency in administration (taking it at the same time each day) is key to maximizing its benefits. Taking it with food may help mitigate certain side effects, and consuming it earlier in the day can help prevent nighttime bathroom trips.
  • Continue its usage as prescribed, even if you feel healthy, as discontinuation may lead to a worsening of your condition.

• Side Effects:

  • Common Side Effects: Nausea, dizziness, diarrhea, headaches, cough, flu-like symptoms, fatigue, increased potassium level in blood, and increased creatinine level in blood. If these symptoms persist or become severe, consult your doctor.
  • Serious Side Effects: Seek immediate medical attention if you experience severe dizziness, fainting, a rapid or irregular heartbeat, swelling in your feet, difficulty breathing, or symptoms of angioneurotic edema (swollen face, tongue, or throat, difficulty swallowing, hives).

• Precautions:

  • Inform your doctor about any pre-existing kidney, liver, or heart conditions, or if you have difficulty urinating, low blood pressure, coronary heart disease, high serum potassium levels, type 2 diabetes mellitus, or anuria.
  • Disclose all other medications you are taking, including supplements and herbal products, as they may interact with Eplerenone. Interactions can occur with ACE inhibitors, NSAIDs, moderate CYP3A4 inhibitors, lithium, and aspirin, potentially increasing the risk of high potassium levels or affecting blood pressure control.
  • Avoid potassium supplements and potassium-rich foods (such as bananas and broccoli) while on this medication, as it may increase potassium levels in your blood. Your doctor will regularly monitor your kidney function and blood potassium levels.
  • Alcohol consumption can intensify certain side effects.
  • Exercise caution when driving or operating heavy machinery, as this medicine may cause dizziness.
  • If you are pregnant, planning to become pregnant, or breastfeeding, inform your doctor before starting this medicine.

• Storage:

  • Store in a cool and dry place, away from direct sunlight.
  • Keep out of sight and reach of children.
  • Store below 30°C.

EPLEHEF 25 MG Tablet, which contains the active ingredient eplerenone, is a medication primarily used to manage certain cardiovascular conditions. It belongs to a class of drugs known as mineralocorticoid receptor antagonists or aldosterone antagonists.

What is EPLEHEF 25 MG Tablet used for?

EPLEHEF 25 MG Tablet is primarily used to treat high blood pressure (hypertension) and heart failure. It is also prescribed to improve survival in stable patients who have experienced a heart attack and have left ventricular systolic dysfunction (a condition where the heart's main pumping chamber doesn't pump blood as well as it should).

How does EPLEHEF 25 MG Tablet work?

This medication works by blocking the action of a natural hormone in the body called aldosterone. Aldosterone can cause the body to retain sodium and water, which leads to increased blood pressure and fluid buildup. By blocking aldosterone, Eplerenone helps your kidneys remove excess salt and water from your body, thereby lowering blood pressure and reducing the strain on your heart.

What is the usual dosage for EPLEHEF 25 MG Tablet?

The usual starting dose for heart failure after a heart attack is 25 mg once daily, which may be increased to 50 mg once daily within four weeks, depending on how well it's tolerated. For high blood pressure, the recommended starting dose is 50 mg once daily and can be increased to a maximum of 50 mg twice daily if the blood pressure response is inadequate. Your doctor will adjust the dose based on your medical condition and potassium levels.

What are the possible side effects of EPLEHEF 25 MG Tablet?

Common side effects can include dizziness, headache, diarrhea, stomach pain, nausea, cough, flu-like symptoms, and fatigue. More serious, though less common, side effects include high potassium levels (hyperkalemia) and kidney problems. It's important to report any persistent or severe side effects to your doctor.

Is EPLEHEF 25 MG Tablet safe during pregnancy or breastfeeding?

Eplerenone is classified as Pregnancy Category B. It is not known whether eplerenone can harm an unborn baby, and it should only be used during pregnancy if the potential benefit justifies the potential risk to the fetus. It is also not known if eplerenone passes into breast milk. If you are breastfeeding, careful infant monitoring is recommended if you take this medication.

Can EPLEHEF 25 MG Tablet be taken with other medications?

EPLEHEF 25 MG Tablet can interact with various medications. It should not be taken with strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole). Caution is advised with moderate CYP3A4 inhibitors (e.g., erythromycin, fluconazole, verapamil), ACE inhibitors, angiotensin receptor blockers (ARBs), NSAIDs (e.g., ibuprofen, naproxen), and potassium supplements, as these combinations can increase the risk of high potassium levels or reduce the effectiveness of EPLEHEF. Always inform your doctor about all prescription, over-the-counter, herbal, and vitamin supplements you are taking. Avoid consuming grapefruit or grapefruit juice while on this medication.

What precautions should be taken while on EPLEHEF 25 MG Tablet?

Before taking EPLEHEF 25 MG Tablet, inform your doctor if you have kidney or liver problems, diabetes (especially with protein in your urine), or high potassium levels. Regular monitoring of your blood pressure, kidney function, and blood potassium levels is essential. You should avoid potassium supplements and limit your intake of potassium-rich foods. Dizziness is a possible side effect, so exercise caution when driving or operating machinery until you know how the medication affects you. Alcohol consumption may intensify some side effects.

What happens if a dose of EPLEHEF 25 MG Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should EPLEHEF 25 MG Tablet be stored?

EPLEHEF 25 MG Tablet should be stored at room temperature, ideally between 68°F to 77°F (20°C to 25°C). Keep it out of reach of children and pets.