Hifenac Spas

HIFENAC SPAS by INTAS PHARMACEUTICALS LTD

• Name: Hifenac Spas Tablet
• Composition: Each tablet contains Aceclofenac 100 mg and Drotaverine 80 mg.
• Uses: Hifenac Spas is a combination medicine primarily used to relieve abdominal pain and cramps caused by muscle spasms in adults. It is prescribed for severe stomach pain, menstrual cramps (dysmenorrhea), intestinal spasms, renal colic (pain from kidney stones), and discomfort associated with various gastrointestinal disorders such as irritable bowel syndrome and spastic colon. The medicine works by reducing inflammation and relaxing smooth muscles to alleviate pain.
• Dosage and Administration: This medicine should be taken orally as directed by a healthcare professional. It is typically advised to take Hifenac Spas with food to minimize stomach upset. The dosage and duration of treatment will depend on the patient's condition and response to the medication. Patients should adhere to the prescribed dosage and avoid exceeding it without consulting their doctor. Hifenac Spas is generally not recommended for children below 12 years of age.
• Side Effects: Common side effects may include nausea, vomiting, diarrhea, constipation, abdominal discomfort or pain, headache, dizziness, rash, pruritus (severe itching), dry mouth, indigestion, vertigo, insomnia (difficulty sleeping), hypotension (low blood pressure), fast heart rate, sweating, and increased liver enzymes. If any side effects persist or worsen, medical advice should be sought.
• Precautions:
  • Allergies: Do not take Hifenac Spas if allergic to aceclofenac, drotaverine, or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen or aspirin.
  • Pregnancy & Breastfeeding: Consult a doctor before use if pregnant or breastfeeding. It is generally not recommended during the third trimester of pregnancy, as it may harm the unborn baby and delay labor. It is also not recommended for breastfeeding women.
  • Organ Impairment: Use with caution in patients with liver, kidney, or heart conditions. It is contraindicated in severe liver disease, severe kidney disease, or severe heart failure. Long-term use may cause kidney damage.
  • Other Conditions: Exercise caution if you have a history of gastrointestinal ulcers or bleeding, cardiovascular diseases, low blood pressure, asthma, or blood clotting disorders.
  • Alcohol: Avoid alcohol consumption during treatment as it can exacerbate side effects like dizziness and increase the risk of stomach irritation and bleeding.
  • Driving/Operating Machinery: Hifenac Spas may cause dizziness, drowsiness, or vertigo; avoid driving or operating heavy machinery if these symptoms occur.
  • Drug Interactions: Inform your doctor about all other medications, supplements, and herbal products being taken to prevent potential drug interactions. Do not take other NSAIDs for pain relief without medical supervision.
• Storage: Store Hifenac Spas Tablets below 25°C or 30°C, protected from light and moisture. Keep this medicine out of the reach and sight of children and pets.

Frequently Asked Questions about HIFENAC SPAS

HIFENAC SPAS by INTAS PHARMACEUTICALS LTD is a combination medication used to treat pain and spasms. It contains two active ingredients: Drotaverine (an antispasmodic) and Aceclofenac (a non-steroidal anti-inflammatory drug, or NSAID).

What is HIFENAC SPAS used for?

HIFENAC SPAS is primarily used to relieve muscle pain associated with spasms, particularly in adults. It's effective for various conditions including abdominal pain, menstrual cramps (dysmenorrhea), and discomfort from gastrointestinal disorders such as irritable bowel syndrome, spastic colon, intestinal colic, biliary colic, and renal colic.

How does HIFENAC SPAS work?

HIFENAC SPAS works due to its two active ingredients:

• Drotaverine: This is an antispasmodic agent that relaxes smooth muscles in the gastrointestinal, biliary, and urinary tracts. It achieves this by inhibiting an enzyme called phosphodiesterase-IV, which leads to increased levels of cyclic adenosine monophosphate (cAMP), causing muscle relaxation and relieving spasms.
• Aceclofenac: This is an NSAID that works by blocking cyclooxygenase (COX) enzymes, particularly COX-2. This action reduces the production of prostaglandins, which are chemical messengers responsible for causing pain, inflammation, swelling, and fever.

Together, these ingredients reduce pain and relax muscles for faster relief.

What is the usual dosage for HIFENAC SPAS?

The dosage of HIFENAC SPAS should be taken as directed by your doctor, as it can vary based on your condition and response to the medicine. For adults, a common dosage is one tablet, 2-3 times a day, preferably with food to help prevent stomach upset. It's crucial to adhere to the prescribed dosage and not exceed it without consulting your doctor.

What are the possible side effects of HIFENAC SPAS?

Common side effects of HIFENAC SPAS may include nausea, vomiting, diarrhea, dry mouth, dizziness, headache, abdominal discomfort, constipation, and changes in pulse rate. Some individuals may also experience vertigo, sleep disorders, allergic skin reactions, or a fall in blood pressure. If any side effects persist or worsen, consult your doctor.

Is HIFENAC SPAS safe during pregnancy or breastfeeding?

HIFENAC SPAS is generally not recommended for use in pregnant women, especially during the first trimester. It should be used with caution during pregnancy and only if considered necessary by your doctor.

For breastfeeding women, caution is also advised. It is not recommended to take HIFENAC SPAS while breastfeeding unless specifically advised by a doctor. Small amounts of medication can pass into breast milk, and it's important to monitor the baby for any adverse reactions.

Can HIFENAC SPAS be taken with other medications?

HIFENAC SPAS can interact with several other medications. It's important to inform your doctor about all medicines, supplements, or herbal remedies you are currently taking. Notable interactions include:

• Other NSAIDs (e.g., ibuprofen, naproxen): Concomitant use can increase the risk of stomach ulcers or bleeding.
• Anticoagulants and antiplatelet agents (e.g., warfarin, clopidogrel): Increased risk of excessive bleeding.
• Diuretics (e.g., furosemide): May affect kidney function.
• Levodopa: Drotaverine may reduce the action of levodopa.
• Medicines for heart problems or high blood pressure: May require dose adjustment and more frequent monitoring.
• Medicines for mental health problems: Such as fluoxetine, lithium.
• Anti-diabetic medicines: Such as glibenclamide.

Avoid taking other painkillers like paracetamol along with HIFENAC SPAS without your doctor's advice, as it could lead to an overdose of NSAIDs and potentially affect the liver.

What precautions should be taken?

• Allergies: Do not take HIFENAC SPAS if you are allergic to aceclofenac, drotaverine, aspirin, or any other NSAIDs.
• Pre-existing conditions: Inform your doctor if you have a history of stomach ulcers, bleeding problems, severe heart failure, high blood pressure, heart problems, high cholesterol, diabetes, asthma, porphyria, or liver and kidney problems.
• Driving and operating machinery: This medicine may cause dizziness or sleepiness, so avoid driving or operating heavy machinery until you know how it affects you.
• Alcohol: Avoid alcohol consumption while taking HIFENAC SPAS, as it can worsen side effects like dizziness and may increase the risk of stomach bleeding.
• Children and Elderly: Caution is advised when giving HIFENAC SPAS to children, and it is generally not recommended for those under 12 or 18 years of age depending on the source, consult your doctor for suitable alternatives. Older patients should take it under medical supervision due to increased susceptibility to side effects.
• Long-term use: HIFENAC SPAS is generally not recommended for long-term use and should be used for the shortest duration necessary to relieve symptoms, as prolonged use can lead to complications like stomach bleeding and kidney problems.

What happens if a dose is missed?

If you miss a dose of HIFENAC SPAS, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should HIFENAC SPAS be stored?

HIFENAC SPAS tablets should be stored at room temperature, ideally below 30°C or 25°C, away from heat, direct light, and moisture. Keep this medicine out of the reach of children and pets.