Razel 40 Mg Tablet (10 Tab)

RAZEL 40 MG TABLET

RAZEL 40 MG TABLET, manufactured by J.B. CHEMICALS & PHARMACEUTICALS LTD., is a medication primarily used to manage high cholesterol and triglyceride levels.

Name

• Common Name: Rosuvastatin
• Brand Name: Razel 40 Tablet

Composition

RAZEL 40 MG TABLET contains Rosuvastatin 40 mg as its active ingredient. Rosuvastatin belongs to a class of drugs called statins, which work by inhibiting an enzyme in the liver necessary for cholesterol production.

Uses

This medicine is prescribed for:

• Lowering high levels of "bad" low-density lipoprotein (LDL) cholesterol and triglycerides.
• Increasing "good" high-density lipoprotein (HDL) cholesterol.
• Reducing the risk of cardiovascular events such as heart attacks and strokes.
• Managing familial hypercholesterolemia (a genetic condition causing high cholesterol).
• Slowing the progression of atherosclerosis (buildup of fatty deposits in arteries).

Dosage and Administration

RAZEL 40 MG TABLET should be taken once daily, with or without food, as directed by a healthcare professional. The tablet should be swallowed whole with a glass of water and not crushed or chewed. Consistency is important, so it is recommended to take it at the same time each day. The usual starting dose for managing high cholesterol is 40 mg once daily, and the doctor may adjust the dose based on individual cholesterol levels.

Side Effects

Common Side Effects:

• Headache
• Muscle pain (myalgia) or weakness
• Stomach discomfort, abdominal pain, or nausea
• Dizziness
• Constipation
• Asthenia (lack of energy)

Serious Side Effects (Seek immediate medical attention if you experience):

• Widespread allergic skin reactions or fever
• Severe muscle pain, tenderness, or weakness (signs of myopathy or rhabdomyolysis), especially if accompanied by dark-colored urine or yellowing of the skin (liver damage).

Precautions

• Pregnancy and Breastfeeding: RAZEL 40 MG TABLET is contraindicated during pregnancy and breastfeeding as it may harm the fetus or nursing infant. Women of childbearing age should use reliable contraceptive methods.
• Medical Conditions: Inform your doctor if you have liver problems, kidney problems, diabetes, musculoskeletal disorders, or hypothyroidism. Regular monitoring of liver enzymes may be necessary.
• Alcohol Consumption: Avoid excessive alcohol intake, as it can increase the risk of liver side effects.
• Drug Interactions: Inform your doctor about all other medications you are taking, including fibrates, certain antibiotics, antifungal medications, immunosuppressants (like cyclosporine), anti-HIV medicines (e.g., lopinavir, ritonavir, atazanavir), and blood thinners (e.g., warfarin).
• Food Interactions: Avoid consuming grapefruit and grapefruit juice.
• Driving and Operating Machinery: This medicine may cause dizziness, so caution is advised when driving or operating machinery.

Storage

Store RAZEL 40 MG TABLET at or below 25°C or below 30°C in a cool and dry place. Protect it from moisture and direct sunlight. Keep it out of the sight and reach of children and pets.

Here are some frequently asked questions about RAZEL 40 MG TABLET (Rosuvastatin):

What is RAZEL 40 MG TABLET used for?

RAZEL 40 MG TABLET, containing Rosuvastatin, is primarily used to lower high levels of "bad" cholesterol (LDL) and triglycerides in the blood and to increase "good" cholesterol (HDL). It is also prescribed to reduce the risk of cardiovascular events such as heart attacks and strokes, especially in individuals with high cholesterol, a history of heart disease, or other risk factors like diabetes. It can also help slow the progression of atherosclerosis (buildup of fatty deposits in arteries).

How does RAZEL 40 MG TABLET work?

RAZEL 40 MG TABLET belongs to a class of medicines called statins. It works by blocking an enzyme in the liver called HMG-CoA reductase, which is essential for the body to produce cholesterol. By inhibiting this enzyme, it reduces the production of cholesterol, thereby lowering "bad" LDL cholesterol and triglycerides, and helping to raise "good" HDL cholesterol. This action helps clear cholesterol from the blood and prevents its buildup in blood vessels, which can lead to blockages.

What is the usual dosage for RAZEL 40 MG TABLET?

The usual starting dose for managing high cholesterol is typically once daily. Your doctor will determine the correct dosage based on your cholesterol levels and individual risk factors, with a maximum daily dose of 40 mg. It can be taken at any time of the day, with or without food, but it's recommended to take it at the same time each day for consistency.

What are the possible side effects of RAZEL 40 MG TABLET?

Common side effects of RAZEL 40 MG TABLET include headache, muscle pain or weakness (myalgia/asthenia), stomach discomfort, nausea, dizziness, constipation, and joint pain. Most of these are usually mild and temporary. In rare cases, more serious side effects like severe muscle pain, muscle breakdown (rhabdomyolysis), or liver damage can occur. You should consult your doctor if any side effects persist or worsen, or if you experience unusual muscle pain, dark urine, or yellowing of the skin or eyes.

Is RAZEL 40 MG TABLET safe during pregnancy or breastfeeding?

No, RAZEL 40 MG TABLET is considered unsafe and is contraindicated during pregnancy and breastfeeding. Rosuvastatin, the active ingredient, may cause harm to a developing baby or nursing infant. Women of childbearing age should use reliable contraception while taking this medication.

Can RAZEL 40 MG TABLET be taken with other medications?

RAZEL 40 MG TABLET can interact with several medications. Inform your doctor about all medicines, supplements, or herbal products you are taking.

• Antacids containing aluminum or magnesium may reduce the absorption of Rosuvastatin; take them at least 2 hours after RAZEL 40 MG TABLET.
• Combining with other cholesterol-lowering medications like fibrates (e.g., gemfibrozil) or ezetimibe can increase the risk of muscle problems.
• Blood thinners like warfarin can have their effects increased, raising the risk of bleeding.
• Cyclosporine (an immune suppressant) can increase the risk of muscle and kidney problems.
• Protease inhibitors (e.g., ritonavir, atazanavir) used for HIV can increase rosuvastatin levels and the risk of side effects.
• Antibiotics (e.g., erythromycin, clarithromycin) and antifungals (e.g., ketoconazole) may also interact.

What precautions should be taken while taking RAZEL 40 MG TABLET?

Before taking RAZEL 40 MG TABLET, inform your doctor if you have any liver problems, kidney problems, diabetes, or a history of muscle disorders. Regular monitoring of liver enzymes and blood sugar levels may be necessary. Avoid or limit grapefruit consumption as it can increase the levels of rosuvastatin in the blood. Excessive alcohol intake should also be avoided as it can increase the risk of liver damage. Maintaining a healthy lifestyle with a balanced diet and regular exercise is crucial for best results.

What happens if a dose of RAZEL 40 MG TABLET is missed?

If you miss a dose of RAZEL 40 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose (e.g., within 12 hours), skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.

How should RAZEL 40 MG TABLET be stored?

RAZEL 40 MG TABLET should be stored in a cool and dry place, away from direct sunlight and moisture. Keep it out of sight and reach of children. Typically, it should be stored at or below 25°C or 30°C.