Levomac Oz

LEVOMAC OZ

• Name: LEVOMAC OZ

• Manufacturer: MACLEODS PHARMACEUTICALS LTD

• Composition: LEVOMAC OZ is a combination medicine containing two active ingredients:

  • Levofloxacin (250 mg)
  • Ornidazole (500 mg)

• Uses: LEVOMAC OZ is primarily used to treat diarrhea and dysentery caused by bacterial and parasitic infections. It is also prescribed for various other bacterial and protozoal infections, including:

  • Gastrointestinal infections
  • Chest infections
  • Urinary tract infections
  • Pneumonia
  • Bronchitis
  • Intestinal, vaginal, and genital infections Levofloxacin works by inhibiting bacterial cell division and repair, while Ornidazole kills parasites and anaerobic bacteria by damaging their DNA. This medicine is not effective against viral infections like the common cold or flu.

• Dosage and Administration: Take LEVOMAC OZ in the dose and duration as advised by your doctor. Swallow the tablet whole with food; do not chew, crush, or break it. It should be taken at a fixed time for better efficacy. Complete the entire course of treatment even if symptoms improve to prevent recurrence and antibiotic resistance. Do not exceed the recommended dose. Not recommended for children under 18 years of age.

• Side Effects: Common side effects include:

  • Nausea, vomiting, stomach pain, loss of appetite
  • Headache, dizziness, sleepiness
  • Diarrhea or constipation
  • Trouble sleeping, indigestion, flatulence
  • Skin rash, itching, increased sweating
  • Painful joints and muscles

  Serious side effects requiring immediate medical attention:

  • Allergic reactions (rashes, itching, swelling, shortness of breath)
  • Severe intestinal problems (watery diarrhea with blood, stomach cramps, high temperature)
  • Inflammation and pain in tendons and ligaments
  • Fits (convulsions)
  • Numbness or tingling sensations

• Precautions:

  • Allergy: Avoid if allergic to Levofloxacin, Ornidazole, or any fluoroquinolone/nitroimidazole antibiotics.
  • Pregnancy and Breastfeeding: Generally not recommended; consult a doctor.
  • Organ Impairment: Use with caution in patients with liver, kidney, or heart problems.
  • Tendons/Muscles: Use with caution if you have a history of tendon disorders or myasthenia gravis, as it may worsen muscle weakness.
  • Central Nervous System: Not recommended for use if you have epilepsy or other central nervous system disorders.
  • Alcohol: Avoid alcohol consumption as it may irritate the stomach and cause excessive drowsiness.
  • Driving/Operating Machinery: Avoid driving or operating machinery if you experience dizziness or sleepiness.
  • Sun Exposure: Avoid excessive sun exposure during treatment and for at least 48 hours after stopping the medicine.
  • Food Interactions: Avoid consuming grapefruit or grapefruit juice as it may interfere with drug absorption.
  • Other Conditions: Do not use if you have blood in your stool or severe constipation.

• Storage: Store below 25°C or 30°C. Protect from moisture and sunlight. Keep out of the sight and reach of children.

LEVOMAC OZ is a combination antibiotic medication manufactured by MACLEODS PHARMACEUTICALS LTD. It contains Levofloxacin and Ornidazole. Levofloxacin is a fluoroquinolone antibiotic, and Ornidazole is a nitroimidazole antibiotic with anti-amoebic and antiprotozoal properties. This combination works to treat various infections caused by bacteria and parasites.

Here are some frequently asked questions about LEVOMAC OZ:

What is LEVOMAC OZ used for?

LEVOMAC OZ is primarily used to treat diarrhea and dysentery caused by mixed bacterial and parasitic infections. It is also prescribed for other bacterial and protozoal infections affecting the gastrointestinal tract, chest, urinary tract, vagina, and genital areas. It is not effective against viral infections like the common cold or flu.

How does LEVOMAC OZ work?

LEVOMAC OZ works through the combined action of its two active ingredients. Levofloxacin, a quinolone antibiotic, inhibits bacterial DNA gyrase, an enzyme vital for bacterial DNA replication, transcription, and repair, thereby killing bacteria or stopping their growth. Ornidazole, an anti-amoebic and antiprotozoal agent, kills harmful bacteria and parasites by damaging their DNA and interfering with their protein formation process.

What is the usual dosage for LEVOMAC OZ?

The dosage of LEVOMAC OZ is determined by your doctor based on your medical condition and the severity of the infection. It should be taken exactly as prescribed, typically as a whole tablet with a glass of water, with or immediately after food to minimize stomach upset. Do not crush, break, or chew the tablet.

What are the possible side effects of LEVOMAC OZ?

Common side effects may include nausea, vomiting, diarrhea, headache, dizziness, loss of appetite, constipation, stomach pain, and trouble sleeping. More serious, though less common, side effects can include allergic reactions (rashes, itching, swelling, breathing difficulties), worsening of muscle weakness in individuals with myasthenia gravis, tendon problems (tendonitis or rupture), seizures, confusion, and increased sensitivity to sunlight. If any side effects persist or worsen, consult your doctor.

Is LEVOMAC OZ safe during pregnancy or breastfeeding?

LEVOMAC OZ is generally not recommended during pregnancy due to limited safety data and potential risks to the developing baby; always consult your doctor if you are pregnant or planning to conceive. Similarly, it is not recommended during breastfeeding, as limited safety data is available, and doctors may advise discontinuing breastfeeding while on this medication.

Can LEVOMAC OZ be taken with other medications?

LEVOMAC OZ can interact with several medications. Inform your doctor about all medicines, supplements, or herbal products you are currently taking. Notable interactions include those with blood thinners (like Warfarin, which can increase bleeding risk), NSAIDs (painkillers that can increase the risk of fits), and antacids containing calcium or magnesium (which should not be taken within two hours of LEVOMAC OZ as they can reduce absorption). It can also interact with medications for psychiatric illnesses, diabetes, gout, and heart rhythm problems.

What precautions should I take while using LEVOMAC OZ?

It is crucial to complete the full course of treatment as prescribed by your doctor, even if your symptoms improve, to prevent the infection from returning and to avoid antibiotic resistance. Avoid consuming alcohol, as it can increase side effects like dizziness. If you experience dizziness, confusion, or fits, refrain from driving or operating machinery. Inform your doctor about any history of fits, tendon problems, myasthenia gravis, or kidney, liver, and heart conditions. It is not recommended for children under 18 years of age. You should also avoid excessive sun exposure and ensure adequate fluid intake along with a healthy diet rich in probiotics and fiber.

What should I do if I miss a dose of LEVOMAC OZ?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should LEVOMAC OZ be stored?

Store LEVOMAC OZ in a cool, dry place, protected from direct sunlight and moisture. Keep it out of the sight and reach of children. The typical storage temperature is below 30°C (or between 10ºC to 25ºC).