Avanair 100mg Tab

AVANAIR 100MG TABLET is a prescription medication manufactured by Cipla Ltd, used for the treatment of erectile dysfunction (ED) in adult men.

Name

• Brand Name: AVANAIR 100MG TABLET
• Common Name: Avanafil

Composition

Each uncoated tablet contains 100 mg of Avanafil. Avanafil is a phosphodiesterase type 5 (PDE5) inhibitor.

Uses

AVANAIR 100MG TABLET is indicated for the treatment of erectile dysfunction (ED), also known as impotence, in adult males. It works by increasing blood flow to the penis, which helps achieve and maintain an erection when sexually stimulated.

Dosage and Administration

• The recommended starting dose is 100 mg, taken orally as needed.
• It should be taken approximately 15 to 30 minutes before sexual activity. Some sources suggest taking it about one hour before.
• Sexual stimulation is required for AVANAIR 100MG TABLET to be effective.
• The maximum recommended dosing frequency is once per day. Do not exceed the prescribed dose.
• AVANAIR 100MG TABLET can be taken with or without food, though a high-fat meal may delay its onset of action.
• Swallow the tablet whole with a full glass of water.

Side Effects

Common Side Effects:

• Headache
• Flushing (sense of warmth in the ears, neck, and face)
• Nasal congestion (stuffy nose) or runny nose
• Back pain
• Nasopharyngitis (inflammation of the nasal passages and throat)
• Dizziness
• Sore throat

Serious Side Effects (seek immediate medical attention if experienced):

• Prolonged erection lasting longer than 4 hours (priapism), which can cause permanent damage to the penis
• Sudden decrease or loss of vision in one or both eyes, including blurred vision
• Sudden decrease or loss of hearing, including ringing in the ears
• Sudden drop in blood pressure
• Chest pain

Precautions

• Contraindications: Do not use AVANAIR 100MG TABLET if you are taking nitrates in any form (e.g., for chest pain), as this can cause a dangerous drop in blood pressure.
• Specific Populations: This medication is exclusively for adult men and is not intended for use by women or children.
• Medical Conditions: Inform your doctor if you have a history of heart conditions (e.g., heart attack within the last 6 months, heart rate disturbances, chest pain), low blood pressure, severe liver or kidney problems, bleeding disorders, peptic ulcers, anatomical deformation of the penis (such as Peyronie's disease), or conditions that may predispose you to priapism (e.g., sickle cell anemia, multiple myeloma, leukemia).
• Drug Interactions:
  • Avoid or limit consumption of grapefruit juice and alcohol, as they can increase the risk of side effects.
  • Inform your doctor if you are taking strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir, clarithromycin) as concomitant use is contraindicated. For moderate CYP3A4 inhibitors (e.g., erythromycin, diltiazem), the maximum recommended dose of Avanafil is 50 mg, not to exceed once every 24 hours.
  • If co-administered with alpha-blockers, ensure you are stable on alpha-blocker therapy before initiating AVANAIR at a 50 mg dose.
• Driving and Machinery: AVANAIR 100MG TABLET may cause dizziness or affect vision. Do not drive or operate heavy machinery if you experience these effects.

Storage

Store AVANAIR 100MG TABLET in a cool, dry place below 30°C. Keep it away from direct sunlight and out of reach of children and pets.

Here are some frequently asked questions about AVANAIR 100MG TAB:

What is AVANAIR 100MG TAB used for?

AVANAIR 100MG TAB, containing Avanafil, is a prescription medicine primarily used to treat erectile dysfunction (ED) in adult men. It helps men achieve and maintain an erection firm enough for satisfactory sexual activity.

How does AVANAIR 100MG TAB work?

AVANAIR 100MG TAB is a phosphodiesterase type 5 (PDE5) inhibitor. During sexual stimulation, nitric oxide (NO) is released in the penis, which activates an enzyme leading to increased levels of cyclic guanosine monophosphate (cGMP). Avanafil enhances the effect of NO by inhibiting PDE5, the enzyme responsible for breaking down cGMP. This increased cGMP relaxes the smooth muscles in the penis, allowing for increased blood flow and resulting in an erection. Sexual stimulation is required for the medication to work.

What is the usual dosage of AVANAIR 100MG TAB?

The recommended starting dose of AVANAIR is 100 mg, taken orally as needed approximately 15 to 30 minutes before sexual activity. Based on individual effectiveness and tolerability, your doctor may adjust the dose, potentially increasing it to 200 mg or decreasing it to 50 mg. The maximum recommended dosing frequency is once per day. It can be taken with or without food.

What are the possible side effects of AVANAIR 100MG TAB?

Common side effects may include headache, flushing (reddening of the face), stuffy or runny nose, sore throat, and back pain. More serious, but uncommon, side effects include an erection lasting more than 4 hours (priapism), sudden vision loss in one or both eyes, or sudden decrease or loss of hearing, which may be accompanied by tinnitus or dizziness. If any of these serious side effects occur, seek immediate medical attention.

Is AVANAIR 100MG TAB safe during pregnancy or breastfeeding?

AVANAIR 100MG TAB is not intended for use in women and should not be used during pregnancy or breastfeeding.

Can AVANAIR 100MG TAB be taken with other medications?

It is crucial to inform your doctor about all medications you are taking. AVANAIR 100MG TAB is contraindicated with nitrates in any form (often prescribed for chest pain) and guanylate cyclase (GC) stimulators (e.g., riociguat), as this combination can cause a dangerous drop in blood pressure.

Additionally, use with caution when taking alpha-blockers or other antihypertensive medications due to the potential for additive blood pressure-lowering effects. Strong CYP3A4 inhibitors (such as ketoconazole, ritonavir, clarithromycin) should not be used with AVANAIR. If you are taking moderate CYP3A4 inhibitors (e.g., erythromycin, diltiazem), the maximum recommended dose of AVANAIR is 50 mg, not to exceed once every 24 hours.

What precautions should be taken with AVANAIR 100MG TAB?

AVANAIR 100MG TAB is only for adult men and should not be used by women or children. Seek immediate medical attention if you experience an erection lasting more than 4 hours (priapism), sudden vision loss, or sudden hearing loss.

Use with caution if you have an anatomical deformation of the penis (like Peyronie's disease), conditions that may predispose to priapism (e.g., sickle cell anemia, multiple myeloma, leukemia), bleeding disorders, or active peptic ulcers. It is not recommended for patients with severe heart, kidney, or liver problems. Avoid consuming excessive alcohol or grapefruit juice while taking this medication. Sexual stimulation is necessary for AVANAIR to be effective.

What happens if a dose of AVANAIR 100MG TAB is missed?

AVANAIR is taken on an as-needed basis before sexual activity, not as a daily medication. If you miss a dose, simply take it when you remember, provided it is within the appropriate timeframe before sexual activity. Do not take more than one dose within a 24-hour period, and do not double the dose to make up for a missed one.

How should AVANAIR 100MG TAB be stored?

Store AVANAIR 100MG TAB in a cool, dry place, typically below 30°C, away from direct sunlight and moisture. Keep it out of the reach and sight of children and pets.