Teneza M 1000 Mg Tablet (15 Tab)

TENEZA M 1000 MG TABLET

TENEZA M 1000 MG TABLET is an antidiabetic agent manufactured by Torrent Pharmaceuticals Ltd. It is used to manage type 2 diabetes mellitus.

• Composition: Each tablet contains a combination of two active ingredients:

  • Metformin (1000 mg)
  • Teneligliptin (20 mg)

• Uses: TENEZA M 1000 MG TABLET is prescribed for adults with type 2 diabetes mellitus to improve glycemic control. It is particularly useful when diet and exercise alone are insufficient, or when patients do not respond well to Metformin alone. The medication works by decreasing liver glucose production, lowering intestinal glucose uptake, and increasing insulin levels while reducing glucagon levels in the body. This helps in controlling blood sugar levels and can reduce the risk of long-term diabetes complications such as kidney damage, nerve problems, vision impairment, heart disease, and stroke.

• Dosage and Administration: The typical dosage is one tablet taken orally once or twice daily, as advised by a physician. It is recommended to take the tablet with meals to minimize gastrointestinal side effects. The tablet should be swallowed whole with a glass of water and not crushed, chewed, or broken. Consistent daily intake at the same time is advised for optimal benefits.

• Side Effects: Common side effects may include nausea, vomiting, diarrhea, headache, stomach ache, respiratory infection, weight gain, and sweating. More serious, though rare, side effects can include lactic acidosis (buildup of lactic acid in the blood) and Vitamin B12 deficiency with long-term use.

• Precautions: Inform your doctor about any pre-existing medical conditions, especially kidney, liver, or heart problems, severe infection, or if you are pregnant or breastfeeding. Excessive alcohol consumption should be avoided as it increases the risk of lactic acidosis. The medicine is not recommended for patients with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis. Regular monitoring of blood sugar levels and kidney function is crucial during treatment.

• Storage: Store the medicine in a cool and dry place, away from direct sunlight, and out of the sight and reach of children. It should be stored at 10ºC to 25ºC or below 30ºC.

TENEZA M 1000 MG TABLET is a combination medication containing Teneligliptin and Metformin. It is used to manage high blood sugar levels in adults with type 2 diabetes mellitus.

Here are some frequently asked questions about TENEZA M 1000 MG TABLET:

What is TENEZA M 1000 MG TABLET used for?

TENEZA M 1000 MG TABLET is primarily used to treat type 2 diabetes mellitus in adults. It is often prescribed when diet and exercise alone are not sufficient, or when metformin alone does not adequately control blood sugar levels. This medication helps improve blood sugar control and can prevent serious complications associated with diabetes, such as kidney damage, eye problems, nerve issues, and cardiovascular diseases.

How does TENEZA M 1000 MG TABLET work?

TENEZA M 1000 MG TABLET contains two active ingredients: Teneligliptin and Metformin.

• Metformin (a biguanide) works by reducing the amount of glucose produced by the liver, decreasing the absorption of glucose from the intestines, and improving the body's sensitivity to insulin, thereby increasing glucose uptake and utilization by cells.
• Teneligliptin (a dipeptidyl peptidase-4 (DPP-4) inhibitor) works by increasing the levels of incretin hormones in the body, which, in turn, increases insulin release from the pancreas and reduces glucagon levels (a hormone that raises blood sugar), especially after meals. Together, these actions lead to better control of both fasting and post-meal blood sugar levels.

What is the usual dosage of TENEZA M 1000 MG TABLET?

The dosage of TENEZA M 1000 MG TABLET should always be taken as directed by your doctor. Typically, it is recommended to take one tablet, once or twice daily, with meals to help minimize stomach upset. Do not crush, chew, or break the tablet; swallow it whole with a glass of water. Dosage adjustments may be necessary for elderly patients or those with kidney issues.

What are the possible side effects of TENEZA M 1000 MG TABLET?

Common side effects can include nausea, vomiting, diarrhea, headache, stomach ache, abdominal pain, constipation, bloating, fatigue, and loss of appetite. Some individuals may experience hypoglycemia (low blood sugar), especially if taken with other antidiabetic medications, insulin, or if meals are skipped. A rare but serious side effect is lactic acidosis, which is a buildup of lactic acid in the blood. Symptoms of lactic acidosis can include abdominal pain, muscle cramps, vomiting, severe fatigue, and difficulty breathing, and require immediate medical attention. Long-term use of metformin, a component of TENEZA M, may also lead to Vitamin B12 deficiency.

Is TENEZA M 1000 MG TABLET safe during pregnancy or breastfeeding?

TENEZA M 1000 MG TABLET should be used with caution during pregnancy, and only if the potential benefit outweighs the potential risk to the fetus, as safe use has not been fully established for teneligliptin. Metformin, one of the components, is generally considered safe during pregnancy, either alone or combined with insulin, and passes into breast milk in small amounts without reported side effects in breastfed babies. However, for TENEZA M specifically, it is generally advised that it should not be used by breastfeeding mothers as teneligliptin may pass into breast milk, and insufficient scientific evidence exists regarding its safety in pregnant and breastfeeding populations. Always consult your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Can TENEZA M 1000 MG TABLET be taken with other medications?

TENEZA M 1000 MG TABLET can interact with various medications. Inform your doctor about all medicines you are taking, including over-the-counter drugs and herbal supplements.

• Increased risk of lactic acidosis: Cationic drugs eliminated by renal tubular secretions (e.g., amiloride, digoxin, morphine, procainamide, quinidine, ranitidine, vancomycin) can decrease metformin elimination. Medicines used to treat high blood pressure like enalapril, captopril, candesartan, and losartan may also increase this risk.
• Altered blood glucose lowering effect: Drugs that can enhance the blood glucose-lowering effect (e.g., beta-blockers, MAO inhibitors) or attenuate it (e.g., steroids, thyroid hormones) should be used with caution.
• Other interactions: Antibiotics (rifampicin, tetracycline, clarithromycin), antifungals (fluconazole, ketoconazole), diuretics (furosemide), and certain antidepressants, antihypertensives, and anticonvulsants may interact.

What precautions should be taken?

• Lactic Acidosis: TENEZA M can cause lactic acidosis, a serious condition. Avoid excessive alcohol consumption as it increases this risk.
• Kidney, Liver, and Heart Problems: Inform your doctor if you have any pre-existing kidney, liver, or heart conditions, as TENEZA M should be used with caution or may be contraindicated in such cases.
• Vitamin B12 Deficiency: Long-term use may lower vitamin B12 levels; regular blood tests are recommended to monitor for deficiencies.
• Hypoglycemia: Be aware of symptoms of low blood sugar (e.g., sweating, dizziness, palpitations) and carry quick sources of sugar.
• Other conditions: Inform your doctor if you have severe infection, trauma, type 1 diabetes, severe ketosis, pituitary or adrenal insufficiency, are malnourished, or have a history of abdominal surgery or bowel obstruction.

What happens if a dose is missed?

If you miss a dose of TENEZA M 1000 MG TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one, as this may lead to unpleasant side effects or overdose.

How should it be stored?

Store TENEZA M 1000 MG TABLET in a cool and dry place, protected from direct sunlight, moisture, and heat. Keep it in the container or pack it came in, tightly closed, and out of reach of children and pets.