Daplo V Tablet

DAPLO V TABLET

Daplo V Tablet is a prescription medication manufactured by Dr. Reddy's Laboratories Ltd. for the management of Type 2 Diabetes Mellitus.

Composition Each tablet contains a combination of two active ingredients:

• Dapagliflozin (10 mg)
• Vildagliptin (100 mg)

Uses Daplo V Tablet is prescribed for adults with Type 2 Diabetes Mellitus, used as an adjunct to diet and exercise, to:

• Manage blood sugar levels effectively.
• Reduce the risk of cardiovascular death and hospitalization due to heart failure.
• Assist in treating chronic kidney disease associated with Type 2 Diabetes.

Dosage and Administration

• Take Daplo V Tablet in the precise dose and duration as advised by your doctor.
• Typically, the starting dose is one tablet daily, preferably in the morning.
• It can be taken with or without food, but consistency in timing each day is recommended for best results.
• Swallow the tablet whole; do not chew, crush, or break it. Do not stop taking it without consulting your doctor.

Side Effects Common side effects may include:

• Nausea, vomiting, diarrhea, abdominal pain
• Headache, dizziness, fatigue
• Hypoglycemia (low blood sugar), increased urination, thirst
• Genital infections (yeast infections), urinary tract infections (UTIs)
• Back pain, joint pain

Less common but serious side effects can include diabetic ketoacidosis, Fournier's gangrene, kidney problems, allergic reactions, and liver dysfunction.

Precautions

• Inform your doctor about any existing medical conditions, especially kidney or liver problems, heart issues, or pancreatic disease.
• Disclose all other medications, supplements, and herbal products you are taking to prevent potential drug interactions.
• Avoid alcohol consumption as it may increase the risk of lactic acidosis and hypoglycemia.
• Use with caution if pregnant or breastfeeding; consult your doctor.
• Daplo V Tablet may cause dizziness, so exercise caution when driving or operating machinery.
• This medicine is not recommended for children and is not indicated for Type 1 Diabetes.

Storage Store in a cool and dry place, away from direct sunlight, and out of reach of children and pets. It should be stored below 30°C, away from moisture and excessive heat, and does not require refrigeration.

DAPLO V TABLET, manufactured by Dr. Reddy's Laboratories Ltd., is a combination medication used to manage blood sugar levels in adults with type 2 diabetes mellitus.

What is DAPLO V TABLET used for?

DAPLO V TABLET is primarily used to manage blood sugar levels in adults with type 2 diabetes. It is prescribed as an adjunct to diet and exercise to improve glycemic control. Additionally, it may help reduce the risk of cardiovascular death, hospitalization due to heart failure, and assist in treating chronic kidney disease associated with type 2 diabetes.

How does DAPLO V TABLET work?

DAPLO V TABLET contains two active ingredients: Dapagliflozin and Vildagliptin.

• Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor. It works by preventing the kidneys from reabsorbing glucose back into the bloodstream, leading to excess glucose being excreted through urine, thereby lowering blood sugar levels.
• Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It enhances the levels of incretin hormones in the body, which stimulate insulin release from the pancreas when blood sugar is high and decrease glucagon secretion from the liver. This dual action helps maintain balanced blood sugar levels.

What is the usual dosage of DAPLO V TABLET?

Typically, the starting dose is one tablet daily, usually taken in the morning. The recommended dosage can vary based on individual patient factors, including the severity of the condition, kidney function, and other medications being taken. It's crucial to follow your doctor's instructions regarding the dosage and duration of treatment. The tablet should be swallowed whole with a glass of water and can be taken with or without food.

What are the possible side effects of DAPLO V TABLET?

Common side effects of DAPLO V TABLET may include nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, increased urination, thirst, and hypoglycemia (low blood sugar). Other common side effects include urinary tract infections (UTIs), genital yeast infections, and nasopharyngitis. Less common but potentially serious side effects can include diabetic ketoacidosis and Fournier's gangrene. If any side effects persist or worsen, you should inform your doctor.

Is DAPLO V TABLET safe during pregnancy or breastfeeding?

DAPLO V TABLET is generally not recommended during pregnancy or breastfeeding. Limited information is available on its use in pregnant women, and it's not known if it passes into human breast milk. It is crucial to consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding to discuss potential risks and alternative treatment options.

Can DAPLO V TABLET be taken with other medications?

DAPLO V TABLET may interact with certain medications. It is important to inform your doctor about all other medicines, supplements, and herbal products you are currently taking to avoid potential interactions. For example, taking it with loop diuretics may increase the risk of dehydration and low blood pressure. When used with insulin or insulin secretagogues (like sulfonylureas), there may be an increased risk of low blood sugar, and a dose adjustment may be needed.

What precautions should be taken?

Before starting DAPLO V TABLET, inform your doctor about any existing medical conditions, especially kidney or liver problems, heart issues, or a history of pancreatic disease. Regular monitoring of blood sugar levels is recommended. You should avoid excessive alcohol consumption, as it can increase the risk of hypoglycemia and lactic acidosis. Be aware of the symptoms of low blood sugar and carry a source of fast-acting sugar. If you experience unusual symptoms like blisters or ulcers on your foot, consult your doctor immediately.

What happens if a dose is missed?

If you miss a dose of DAPLO V TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should DAPLO V TABLET be stored?

DAPLO V TABLET should be stored in its original packaging at a room temperature between 15-30°C, away from direct heat and sunlight. It should be kept dry and out of the reach of children. Always check the expiry date on the pack.