Epifast Rtu 500

EPIFAST RTU 500 Infusion

EPIFAST RTU 500 is a specialized anti-epileptic medication manufactured by Mankind Pharma Ltd..

• Name: EPIFAST RTU 500 Infusion (Brand Name)
• Composition: The active ingredient is Levetiracetam, present at 500 mg per 100 ml. Levetiracetam is an antiepileptic medication that works by attaching to specific sites (SV2A) on nerve cell surfaces, suppressing abnormal activity and preventing the spread of electrical signals that cause seizures.
• Uses: EPIFAST RTU 500 Infusion is prescribed for the treatment of epilepsy and various types of seizures, including partial-onset seizures, myoclonic seizures, and primary generalized tonic-clonic (grand mal) seizures. It is generally used for short-term control of seizures when oral medication is not feasible, for instance, when a patient is unconscious.
• Dosage and Administration: This medicine is administered intravenously as a 15-minute infusion by a healthcare professional; it should not be self-administered. The doctor determines the appropriate dosage and duration of treatment based on the patient's medical condition and response.
• Side Effects: Common side effects may include drowsiness, disturbed sleep, light-headedness, dizziness, sleepiness, general weakness, headache, fatigue, decreased appetite, infection, nasopharyngitis, and injection site reactions. Behavioral changes, such as aggression, irritation, agitation, and mood swings, have also been reported. Patients should be monitored for suicidal thoughts or actions.
• Precautions:
  • Allergies: Not recommended for use if allergic to Levetiracetam or any other component.
  • Medical Conditions: Inform your doctor if you have severe kidney disease, lung disease, muscle weakness (myasthenia gravis), severe liver disease, or issues with alcohol or other prescription drugs. Dose adjustments may be needed for kidney impairment.
  • Pregnancy & Breastfeeding: Consult a doctor before use if pregnant or breastfeeding. Limited data suggests potential risks during pregnancy, and it may pass into breast milk.
  • Alcohol: Avoid consuming alcohol as it can increase side effects like drowsiness and dizziness.
  • Activities: Due to potential dizziness and decreased alertness, avoid driving or operating heavy machinery until you know how the medicine affects you.
  • Discontinuation: Do not stop the medication abruptly, as this can lead to withdrawal symptoms or worsen seizures.
• Storage: Store EPIFAST RTU 500 Infusion in a cool and dry place, away from direct sunlight. Keep it out of the sight and reach of children. It should be stored at 10ºC to 25ºC or below 30ºC.

Here are the frequently asked questions about EPIFAST RTU 500 Infusion by MANKIND PHARMA LTD., also known by its active ingredient, Levetiracetam:

1. What is EPIFAST RTU 500 Infusion used for?

EPIFAST RTU 500 Infusion is an anti-epileptic medicine primarily used to treat seizures (fits) in individuals with epilepsy. It is effective for various types of seizures, including partial-onset seizures, myoclonic seizures, and primary generalized tonic-clonic seizures. It helps reduce the frequency and severity of these epileptic fits.

2. How does EPIFAST RTU 500 Infusion work?

This medicine contains Levetiracetam as its active ingredient. It works by slowing down abnormal electrical signals in the brain that cause seizures. It achieves this by attaching to specific sites (SV2A) on the surfaces of nerve cells, which suppresses the abnormal activity of these cells and prevents the spread of electrical signals that lead to seizures.

3. How is EPIFAST RTU 500 Infusion administered and what is the usual dosage?

EPIFAST RTU 500 Infusion is a parenteral medicine administered intravenously (as a slow drip) into a vein over 15 minutes by a healthcare professional. It is typically used for short-term seizure control when oral medication is not feasible, such as when a patient is unconscious. The doctor determines the specific dosage and duration based on the patient's medical condition and response to treatment. It should not be self-administered.

4. What are the common side effects of EPIFAST RTU 500 Infusion?

Common side effects include drowsiness, dizziness, sleepiness, light-headedness, general weakness, headache, decreased appetite, and injection site reactions. Behavioral changes such as irritation, aggressive behavior, and agitation can also occur. A small number of patients have reported suicidal thoughts, so any sudden changes in mood or behavior should be reported to a doctor.

5. Is EPIFAST RTU 500 Infusion safe during pregnancy or breastfeeding?

During Pregnancy: EPIFAST RTU 500 Infusion may be unsafe during pregnancy. While limited human data exists, animal studies have shown potential harmful effects on the developing baby. It is crucial not to stop taking the medication if you become pregnant, but consult your doctor immediately. Your doctor will weigh the benefits against the potential risks and may recommend a high dose of folic acid. During Breastfeeding: Levetiracetam passes into breast milk. While generally considered probably safe if prescribed and taken with caution, infants should be monitored for drowsiness, poor feeding, or inadequate weight gain. Some sources advise against its use during breastfeeding due to potential harm to the infant, while others indicate that side effects are rare and the benefits of continued treatment for the mother often outweigh the risks. It is important to discuss this with your doctor.

6. Can EPIFAST RTU 500 Infusion be taken with other medications or substances?

You should avoid consuming alcohol while on treatment with EPIFAST RTU 500 Infusion, as it can increase side effects like drowsiness and dizziness. Severe drug interactions have been noted with Ketamine and Sodium oxybate. It is important to inform your doctor about all other medications you are taking to avoid potential interactions.

7. What precautions should be taken while using EPIFAST RTU 500 Infusion?

Inform your doctor if you have kidney disease (as dosage adjustment may be needed), liver disease, lung disease, muscle weakness (myasthenia gravis), or a history of suicidal thoughts or depression. Since the infusion can cause dizziness or sleepiness, avoid driving or operating heavy machinery until you know how the medicine affects you. Do not stop the medication abruptly without consulting your doctor, as this can lead to withdrawal symptoms or worsening of seizures. This medication is not recommended for children below 16 years of age.

8. What should I do if I miss a dose of EPIFAST RTU 500 Infusion?

Since EPIFAST RTU 500 Infusion is administered by a healthcare professional, a missed dose is less likely. However, if a scheduled infusion is missed, it's crucial to contact your doctor or nurse as soon as possible to reschedule. Missing doses can trigger seizures, so it's important to maintain the prescribed schedule. Never take a double dose to make up for a missed one.

9. How should EPIFAST RTU 500 Infusion be stored?

EPIFAST RTU 500 Infusion should be stored in a cool and dry place, away from direct sunlight. It should be kept out of the sight and reach of children. The recommended storage temperature is typically between 10ºC and 25ºC, or below 30ºC.