Olmezest Am 40 Mg Tablet (10 Tab)

OLMEZEST AM 40 MG TABLET

OLMEZEST AM 40 MG TABLET is a prescription medicine manufactured by SUN PHARMA LABORATORIES LTD.

• Name: Olmezest AM 40 Tablet (Brand Name)

• Composition: Each tablet contains two active ingredients:

  • Olmesartan Medoxomil 40 mg: An angiotensin II receptor blocker (ARB) that relaxes blood vessels.
  • Amlodipine 5 mg: A calcium channel blocker (CCB) that inhibits calcium entry into vascular smooth muscle cells, widening blood vessels and reducing the heart's workload.

• Uses: OLMEZEST AM 40 TABLET is primarily used for:

  • Managing hypertension (high blood pressure).
  • Reducing the risk of cardiovascular events such as heart attacks and strokes, particularly in individuals whose blood pressure is not adequately controlled with either ingredient alone.

• Dosage and Administration:

  • Typically, one tablet is taken once daily, as prescribed by your doctor.
  • It can be taken with or without food.
  • For optimal benefits, it is recommended to take the tablet at the same time each day to maintain consistent blood levels.
  • Do not stop taking this medicine suddenly without consulting your doctor.

• Side Effects:

  • Common Side Effects: Dizziness, headache, fatigue, nausea, and swelling of the ankles or feet.
  • Serious Side Effects: Severe allergic reactions (skin rash, itching, swelling of the face, mouth, or larynx), severe dizziness or light-headedness and fainting (signs of hypotension), severe, persistent diarrhea with substantial weight loss, and yellowing of the whites of the eyes, dark urine, and itching of the skin (signs of liver problems).

• Precautions:

  • Pregnancy and Breastfeeding: Contraindicated in pregnancy and generally not recommended during breastfeeding. Consult a doctor.
  • Alcohol: Avoid alcohol consumption as it may enhance the blood pressure-lowering effect and cause dizziness.
  • Liver/Kidney/Heart Conditions: Use with caution in patients with liver disease, severe kidney disease, or heart problems like congestive heart failure, severe aortic stenosis, or severe obstructive coronary artery disease.
  • Drug Interactions: Inform your doctor about all ongoing medications. Interactions may occur with other antihypertensives, potassium supplements or potassium-sparing diuretics, lithium, and Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).
  • Food Interactions: Avoid consuming grapefruit or grapefruit juice, as it can increase amlodipine levels and lead to an unpredictable decrease in blood pressure.
  • Children: Not recommended for use in children and adolescents under 18 years of age.
  • Driving: May cause dizziness or sleepiness, affecting the ability to drive or operate machinery.

• Storage:

  • Store below 30°C in a cool and dry place.
  • Keep out of sight and reach of children and pets.

What is Olmezest AM 40 Tablet used for?

Olmezest AM 40 Tablet is a combination medicine primarily used to treat high blood pressure (hypertension). It is prescribed when blood pressure is not adequately controlled by either olmesartan or amlodipine alone. By lowering blood pressure, it helps to reduce the risk of cardiovascular events such as heart attacks and strokes.

How does Olmezest AM 40 Tablet work?

Olmezest AM 40 Tablet contains two active ingredients: Olmesartan Medoxomil and Amlodipine. Olmesartan Medoxomil is an angiotensin II receptor blocker (ARB) that works by blocking the hormone angiotensin II, which causes blood vessels to narrow. By blocking this, it relaxes and widens blood vessels. Amlodipine is a calcium channel blocker (CCB) that inhibits the influx of calcium ions into heart and blood vessel cells, leading to relaxation of blood vessels and a reduction in the heart's workload. Together, these actions promote smoother blood flow and make it easier for the heart to pump blood throughout the body, effectively lowering blood pressure.

What is the usual dosage of Olmezest AM 40 Tablet?

The dosage of Olmezest AM 40 Tablet is determined by your doctor based on your blood pressure level and how you respond to the medicine. It is typically taken once daily. The tablet can be taken with or without food, but it is recommended to take it at the same time each day to maintain a consistent level in the blood. Do not chew, crush, or break the tablet; swallow it whole with a glass of water.

What are the possible side effects of Olmezest AM 40 Tablet?

Common side effects of Olmezest AM 40 Tablet include dizziness, headache, tiredness, sleepiness, swelling in the ankles or feet (peripheral edema), nausea, and upset stomach. Other reported side effects may include body pain, chills, nasal congestion, diarrhea, dry mouth, increased urination, skin rash, and an increase in heartbeat. If any of these side effects persist or worsen, consult your doctor.

Is Olmezest AM 40 Tablet safe during pregnancy or breastfeeding?

Olmezest AM 40 Tablet is generally considered unsafe and is not recommended for use during pregnancy, especially after the first trimester, as it can cause serious harm to the developing baby. If you become pregnant while taking this medicine, discontinue it and consult your doctor immediately. For breastfeeding mothers, Olmezest AM 40 Tablet is also not recommended as its components can pass into breast milk and may affect the infant. Your doctor may suggest an alternative treatment if you are breastfeeding.

Can Olmezest AM 40 Tablet be taken with other medications?

It is crucial to inform your doctor about all other medications, supplements, or herbal products you are currently taking, as Olmezest AM 40 Tablet can interact with certain drugs. Interactions can occur with other antihypertensive medicines, diuretics (water pills), potassium supplements, potassium-sparing diuretics, lithium, and Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) like ibuprofen. Concurrent use with aliskiren is not recommended, particularly in patients with diabetes or moderate to severe kidney impairment. Grapefruit juice should also be avoided as it can increase the absorption of amlodipine, potentially leading to an excessive drop in blood pressure.

What precautions should be taken while taking Olmezest AM 40 Tablet?

Several precautions should be observed while taking Olmezest AM 40 Tablet:

• Kidney and Liver Conditions: Use with caution if you have kidney or liver problems; your doctor may monitor your kidney and liver functions.
• Dizziness/Drowsiness: The medicine may cause dizziness or sleepiness, so avoid driving or operating heavy machinery until you know how it affects you. Rise slowly from sitting or lying positions to prevent lightheadedness.
• Potassium Levels: Olmezest AM 40 Tablet may increase potassium levels in the blood. Avoid potassium supplements and potassium-rich foods (e.g., bananas, broccoli) unless advised by your doctor.
• Alcohol: Avoid alcohol consumption as it can further lower blood pressure and increase dizziness.
• Sudden Discontinuation: Do not stop taking the medicine suddenly without consulting your doctor, as it can cause your blood pressure to rise, increasing the risk of heart attack or stroke.

What happens if a dose is missed?

If you miss a dose of Olmezest AM 40 Tablet, take it as soon as you remember. However, if it's nearly time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this may increase the risk of side effects.

How should it be stored?

Olmezest AM 40 Tablet should be stored at room temperature, away from direct sunlight, heat, and moisture. Keep it out of sight and reach of children and pets.