Pregalin M 150mg Cap

PREGALIN M 150MG CAP is a medication manufactured by Torrent Pharmaceuticals Ltd., primarily used for the management of neuropathic pain.

Name

• Brand Name: PREGALIN M 150MG CAPSULE
• Common Name: Pregabalin and Methylcobalamin Capsules

Composition

Each capsule contains a combination of two active ingredients:

• Pregabalin: 150 mg
• Methylcobalamin: 750 mcg (which is a form of Vitamin B12)

Uses

PREGALIN M 150MG CAP is prescribed for various medical conditions, mainly involving nerve-related pain:

• Neuropathic Pain: This includes chronic pain resulting from nerve damage due to conditions such as diabetes, shingles (postherpetic neuralgia), spinal cord injuries, and herpes infection. It works by reducing pain signals from damaged nerves to the brain and helps in calming overactive nerves.
• Epilepsy: Pregabalin, one of its components, is an anticonvulsant that can help reduce the frequency and severity of seizures as an adjunctive therapy for partial-onset seizures in adults.
• Fibromyalgia: It is also used to treat the muscle pain and stiffness associated with fibromyalgia.
• Generalized Anxiety Disorder (GAD): Pregabalin can also be indicated for the treatment of GAD in adults.

Dosage and Administration

The typical recommended dosage is usually one capsule taken twice a day, orally with water. It can be taken with or without food, though taking it with food may help reduce stomach upset. It is important to take the medicine at the same time each day to maintain a consistent level in the body. The exact dosage and duration will be determined by a doctor based on the patient's condition and response to treatment. It should not be crushed, chewed, or broken. Do not stop taking PREGALIN M 150MG CAP abruptly without consulting a doctor, as this can lead to withdrawal symptoms and may worsen the condition.

Side Effects

Common side effects may include:

• Dizziness, drowsiness, fatigue
• Blurred vision, vision problems
• Nausea, vomiting, diarrhea, constipation
• Headache
• Weight gain, increased appetite
• Dry mouth
• Swelling in arms or feet (fluid retention)
• Mood changes, confusion

Serious side effects, though rare, warrant immediate medical attention:

• Severe allergic reactions (skin rash, itching, swelling of face, lips, throat, difficulty breathing)
• Unexplained muscle pain, tenderness, or weakness (symptoms of elevated creatine kinase)
• Suicidal thoughts or behavior.

Precautions

• Alcohol: Avoid consuming alcohol as it can increase the risk of dizziness and drowsiness and impair motor skills.
• Driving and Operating Machinery: Due to potential dizziness and drowsiness, avoid driving or operating heavy machinery until you know how the medication affects you.
• Kidney and Heart Conditions: Use with caution in patients with kidney problems, as the medicine is excreted via urine, and dose adjustments may be necessary. Caution is also advised for patients with heart conditions, as it may increase the risk of heart failure and fluid retention.
• Pregnancy and Breastfeeding: Not recommended for use during pregnancy or breastfeeding unless the potential benefits outweigh the risks, and under strict medical supervision. Women of childbearing age should use effective contraception methods.
• Children and Elderly: Not recommended for children and adolescents below 18 years of age due to lack of safety and efficacy data. Elderly patients should use with special caution as it may increase the risk of accidental injury (falls).
• Withdrawal: Do not discontinue the medication suddenly without consulting a doctor to avoid withdrawal symptoms like headache, mood swings, irritation, anxiety, sleeping difficulties, nausea, and sweating.
• Drug Interactions: Inform your doctor about all other medications, vitamins, and supplements you are currently taking, especially central nervous system depressants, opioids, and some antiepileptic drugs.

Storage

Store PREGALIN M 150MG CAP in a cool, dry place, away from direct sunlight and heat. Keep it out of reach of children and pets.

Here are the most frequently asked questions about PREGALIN M 150MG CAP, along with concise answers.

What is PREGALIN M 150MG CAP used for?

PREGALIN M 150MG CAP is primarily used to treat neuropathic pain, which is pain caused by nerve damage due to conditions like diabetes, shingles (postherpetic neuralgia), or spinal cord injury. It may also be used as an add-on therapy for partial seizures in adults with epilepsy and for the treatment of Generalized Anxiety Disorder (GAD) and fibromyalgia.

How does PREGALIN M 150MG CAP work?

This medicine is a combination of two active ingredients: Pregabalin and Methylcobalamin. Pregabalin works by modulating the activity of calcium channels in nerve cells, which helps to decrease pain signals in the brain. Methylcobalamin, a form of Vitamin B12, supports nerve health by aiding in the production of myelin (a substance that protects nerve fibers) and helps to rejuvenate damaged nerve cells.

What is the usual dosage of PREGALIN M 150MG CAP?

The typical starting dose for Pregabalin, one of the components of PREGALIN M 150MG CAP, is often 150 mg per day, divided into two or three doses. This may be increased by your doctor based on your response and tolerability, up to a maximum of 600 mg per day. It is crucial to follow your doctor's specific dosage instructions and not to exceed the prescribed amount.

What are the possible side effects of PREGALIN M 150MG CAP?

Common side effects can include dizziness, drowsiness, fatigue, blurred vision, weight gain, nausea, headache, dry mouth, and swelling in the arms or feet. More serious, but rare, side effects may include suicidal thoughts, severe allergic reactions (e.g., skin rash, swelling of face/lips/tongue, difficulty breathing), elevated creatine kinase, and vision changes. If you experience any severe or persistent side effects, contact your doctor immediately.

Is PREGALIN M 150MG CAP safe during pregnancy or breastfeeding?

PREGALIN M 150MG CAP is generally not recommended during pregnancy, as animal studies have shown harmful effects on developing babies, and there is limited human data. If you are a woman of childbearing age, effective contraception is advised. It is also probably unsafe during breastfeeding, as it may pass into breast milk and could harm the infant. Always consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding.

Can PREGALIN M 150MG CAP be taken with other medications?

It is important to inform your doctor about all other medications, vitamins, and supplements you are currently taking, as PREGALIN M 150MG CAP can interact with certain drugs. Caution is advised with central nervous system depressants, opioids, and some antiepileptic drugs. Combining it with alcohol can also increase side effects like dizziness and drowsiness.

What precautions should be taken while using PREGALIN M 150MG CAP?

Avoid driving or operating heavy machinery until you know how this medication affects you, as it can cause dizziness and drowsiness. Do not stop taking PREGALIN M 150MG CAP suddenly without consulting your doctor, as abrupt discontinuation can lead to withdrawal symptoms such as anxiety, insomnia, or nausea. Exercise caution if you have kidney disease, heart problems, liver disease, or diabetes, and inform your doctor if you experience any unusual mood changes or suicidal thoughts. This medication is not recommended for individuals under 18 years of age.

What happens if a dose of PREGALIN M 150MG CAP is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects.

How should PREGALIN M 150MG CAP be stored?

Store PREGALIN M 150MG CAP in a cool, dry place, away from direct sunlight and moisture. Keep it out of the sight and reach of children and pets. The medicine should typically be stored below 25°C or 30°C.