Nucoril 5

NUCORIL 5

Name

• Brand Name: Nucoril 5
• Common Name: Nicorandil 5 mg
• Manufacturer: Emcure Pharmaceuticals Ltd.

Composition

Nucoril 5 contains Nicorandil 5 mg as its active ingredient.

Uses

Nucoril 5 is primarily prescribed for the prevention and long-term treatment of angina pectoris (heart-related chest pain), particularly in adults who cannot take beta-blockers or when other anti-anginal medicines are ineffective or unsuitable. It helps manage stable angina, hypertension (high blood pressure), and contributes to maintaining proper heart function. The medicine works by relaxing and widening blood vessels, which improves blood flow and oxygen supply to the heart, thereby reducing its workload.

Dosage and Administration

Nucoril 5 should be taken orally as directed by a healthcare professional. The tablet should be swallowed whole with a glass of water, with or without food, and not crushed, chewed, or broken. It is typically advised to take the medicine regularly, preferably at the same time(s) each day. The specific dose and frequency will be determined by the doctor based on individual medical conditions and response to treatment. Do not discontinue the medication suddenly without consulting your doctor, as this may lead to a recurrence of chest pain.

Side Effects

• Common Side Effects: Headache, dizziness, flushing (a sudden warm feeling and redness on the face and neck), nausea, vomiting, weakness, fatigue, and palpitations (feeling of a fast or irregular heartbeat).
• Serious Side Effects (Rare): May include severely low blood pressure (hypotension), mouth ulcers, or gastrointestinal ulcers which could lead to blood in stools.

Precautions

• Contraindications: Nucoril 5 is contraindicated in individuals with a known allergy to Nicorandil, severe low blood pressure, cardiogenic shock, left ventricular failure with low filling pressure, cardiac decompensation, or pulmonary edema.
• Drug Interactions: Do not take Nucoril 5 concurrently with medicines for erectile dysfunction (such as sildenafil, tadalafil, vardenafil) or pulmonary hypertension (e.g., riociguat), as this can cause a dangerous drop in blood pressure. Alcohol consumption should be avoided as it can increase the risk of severely low blood pressure and dizziness. Caution is advised when used with NSAIDs (e.g., aspirin, naproxen, ibuprofen) due to an increased risk of gastrointestinal ulcers or bleeding.
• Specific Conditions: Consult your doctor if you have a history of liver disease, kidney issues, low blood volume (hypovolaemia), or glaucoma.
• Pregnancy and Breastfeeding: Nucoril 5 is generally not recommended during pregnancy or breastfeeding unless the potential benefits outweigh the risks; always consult a doctor.
• Driving and Machinery: As Nucoril 5 may cause dizziness or weakness, caution should be exercised when driving or operating machinery.
• Not recommended for pediatric use.

Storage

Store Nucoril 5 tablets at a stable room temperature below 25°C or in a refrigerator (2-8°C). Keep the medicine in its original container, tightly closed, and protected from light and moisture. Ensure it is kept out of reach and sight of children.

NUCORIL 5, manufactured by EMCURE PHARMACEUTICALS LTD., is a medication primarily used to treat and prevent angina pectoris, a type of heart-related chest pain caused by reduced blood flow to the heart. It is often prescribed for adults when other heart medications like beta-blockers are not suitable or haven't been effective.

Here are some frequently asked questions about Nucoril 5:

What is Nucoril 5 used for?

Nucoril 5 is used for the prevention and long-term treatment of angina pectoris (heart-related chest pain) and helps maintain proper heart function. Angina occurs due to narrowed blood vessels supplying the heart, leading to insufficient oxygen supply to the heart muscle.

How does Nucoril 5 work?

Nucoril 5 contains Nicorandil, which works as both a potassium channel activator and has nitrate-like effects. It relaxes and widens blood vessels, including the coronary arteries, which improves blood flow and oxygen supply to the heart muscle. This action reduces the heart's workload and oxygen demand, thereby decreasing the frequency and severity of angina attacks.

What is the usual dosage of Nucoril 5?

The daily dose of Nucoril 5 should be taken as directed by your doctor. The dosage can vary based on your condition's intensity and how you respond to the medicine. It should be swallowed whole with water, with or without food, preferably at about the same time each day. Do not crush, chew, or break the tablet.

What are the possible side effects of Nucoril 5?

Common side effects can include headache, dizziness, flushing (a sudden warm feeling and redness on your face and neck), nausea, vomiting, weakness, and fatigue. Some individuals might also experience palpitations (feeling your heartbeat more than usual or irregularly) or an increased heart rate (tachycardia). Most side effects are temporary and usually resolve over time. If symptoms persist or worsen, consult your doctor immediately. Rarely, more serious side effects like mouth ulcers or a significant drop in blood pressure may occur.

Is Nucoril 5 safe during pregnancy or breastfeeding?

Nucoril 5 is generally not recommended during pregnancy unless the benefits outweigh potential risks, and it may be unsafe during breastfeeding as it's unknown if nicorandil passes into breast milk. It is crucial to consult your doctor to discuss all risks and benefits if you are pregnant or breastfeeding.

Can Nucoril 5 be taken with other medications?

Nucoril 5 can interact with certain medications. Taking it with other vasodilators, antihypertensives (like diuretics or ACE inhibitors), or phosphodiesterase-5 (PDE5) inhibitors (such as sildenafil, tadalafil, or vardenafil, used for erectile dysfunction) can increase the risk of significantly low blood pressure. It may also interact with riociguat and certain other medicines. Always inform your doctor about all medicines, including herbal, vitamins, and mineral supplements, you are taking to avoid potential drug interactions.

What precautions should be taken with Nucoril 5?

Avoid consuming alcohol while taking Nucoril 5, as it can cause severely low blood pressure. If you have conditions like low blood pressure (hypotension), hypokalemia (low potassium levels), glaucoma, or severe heart problems, Nucoril 5 should be used with caution. Nucoril 5 may cause dizziness or weakness, so it's advised to be cautious when driving or operating machinery until you know how the medicine affects you. Inform your doctor immediately if you notice blood in your stools or vomit, as it could be due to ulcers.

What happens if a dose is missed?

If you miss a dose of Nucoril 5, take it as soon as you remember. However, if it's nearly time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Always consult your doctor before altering your dosage.

How should Nucoril 5 be stored?

Nucoril 5 tablets should be stored at a stable room temperature, generally below 25°C, and protected from moisture and heat. Some sources suggest storing it in a refrigerator (2-8°C) and not freezing it. Keep the product in its original container, tightly closed, and out of reach of children and pets. Ensure you use the medicine before the expiry date printed on the package.