Fibrodone 200 Mg Tab

FIBRODONE 200 MG TABLET

Name:

• Common Name: Fibrodone 200 mg Tablet
• Brand Name: Fibrodone
• Manufacturer: Lupin Limited

Composition: Each tablet contains Pirfenidone 200 mg as its active ingredient. Pirfenidone belongs to a class of medications known as transforming growth factor inhibitors, anti-fibrotics, or anti-inflammatory agents. It works by reducing the production and accumulation of extracellular matrix proteins, which contribute to the scarring and stiffening of lung tissue, thereby helping to slow disease progression and improve lung function.

Uses: Fibrodone 200 mg Tablet is prescribed for the treatment of Idiopathic Pulmonary Fibrosis (IPF) in adults. IPF is a chronic and progressive lung disease characterized by scarring and inflammation of lung tissues, leading to breathing difficulties.

Dosage and Administration: This medicine should be taken as directed by your doctor. It is typically swallowed whole with water, preferably after a meal, at the same time each day to minimize side effects. Do not crush or chew the tablets. The usual frequency is three times a day, but the exact dosage and duration will be determined by a healthcare professional based on individual factors.

Side Effects:

• Common: Nausea, vomiting, diarrhea, indigestion, loss of appetite, headache, dizziness, fatigue, difficulty sleeping (insomnia), skin reactions after sun exposure (photosensitivity), weight loss, stomach pain, cough, muscle or joint pain, and upper respiratory tract infections.
• Serious: Contact your doctor immediately if you experience severe allergic reactions (e.g., swelling of face, lips, or tongue, wheezing) or signs of liver problems (e.g., yellowing of skin/eyes, dark urine, unusual bruising/bleeding).

Precautions: Fibrodone 200 mg Tablet is not recommended for individuals with severe liver or kidney disorders, or a known allergy to pirfenidone or any other ingredients. It should not be used by children under 18 years of age. Avoid consuming grapefruit juice and refrain from smoking while on this medication, as they can reduce its efficacy. Due to potential photosensitivity, limit sun exposure and use sunscreen and protective clothing. This medicine may cause dizziness or sleepiness, so caution is advised when driving or operating machinery. Liver function tests should be monitored regularly during treatment. Consult your doctor if you are pregnant or breastfeeding.

Storage: Store Fibrodone 200 mg Tablet in its original package at room temperature, ideally at 25°C (with excursions permitted between 15-30°C) or below 30°C. Keep it away from moisture, heat, and direct sunlight, and out of the reach of children. Do not refrigerate.

Here are some frequently asked questions about FIBRODONE 200 MG TAB by Lupin Limited:

What is FIBRODONE 200 MG TAB used for?

FIBRODONE 200 MG TAB is used in adults for the treatment of idiopathic pulmonary fibrosis (IPF). IPF is a specific type of chronic, progressive lung disease where lung tissues become thick, stiff, and scarred, making it difficult to breathe deeply.

How does FIBRODONE 200 MG TAB work?

FIBRODONE 200 MG TAB contains Pirfenidone, an anti-fibrotic agent. It works by reducing scarring and swelling in the lungs by decreasing the release and activity of naturally occurring growth factors and inhibiting transforming growth factors and TNF-alpha, which are involved in fibrosis. This action helps slow down the progression of IPF and makes breathing easier.

What is the usual dosage for FIBRODONE 200 MG TAB?

The tablet is typically taken orally by mouth thrice daily with food. It's often started with a low dose and gradually increased over a two-week period, as directed by your doctor. It's important to take the medicine at the same time each day for optimal benefits and to adhere to the prescribed duration of treatment. Do not chew, crush, or break the tablet.

What are the possible side effects of FIBRODONE 200 MG TAB?

Common side effects can include nausea, rash, upper respiratory tract infection, abdominal pain, dyspepsia, vomiting, gastroesophageal reflux disease (GERD), weight loss, pruritus (itching), headache, dizziness, fatigue, loss of appetite, diarrhea, insomnia, and photosensitivity (increased sensitivity to sunlight). If side effects persist or worsen, consult your doctor.

Is FIBRODONE 200 MG TAB safe during pregnancy or breastfeeding?

FIBRODONE 200 MG TAB is considered unsafe during pregnancy as there is limited information on its safety in pregnant women and animal studies have shown harmful effects on the fetus. It is not known if Pirfenidone passes into breast milk, so it should not be used while breastfeeding for the safety of the breastfed infant. Always consult your doctor if you are pregnant, think you may be pregnant, planning a baby, or breastfeeding.

Can FIBRODONE 200 MG TAB be taken with other medications?

FIBRODONE 200 MG TAB can interact with certain medications. It should not be used in combination with Ciprofloxacin, Teriflunomide, Amiodarone, Rifampicin, Enoxacin, Fluvoxamine, or Propafenone, as this may increase side effects or alter its effectiveness. Inform your doctor about all medicines, supplements, or herbal preparations you are taking to avoid potential interactions.

What precautions should be taken while taking FIBRODONE 200 MG TAB?

Several precautions should be observed:

• Liver and Kidney Issues: Use with caution if you have mild to moderate hepatic or renal impairment; your doctor may monitor liver and kidney function. It is contraindicated in severe liver or kidney disease.
• Sun Sensitivity: This medicine can make your skin sensitive to sunlight (photosensitivity). Avoid prolonged sun exposure, wear protective clothing, and use sunscreen daily.
• Smoking: Avoid smoking during treatment as it can reduce the effectiveness of the medicine.
• Driving and Operating Machinery: It may cause dizziness, sleepiness, or tiredness, so avoid driving or operating machinery until you know how it affects you.
• Alcohol: It is not known whether consuming alcohol affects the drug; consult your doctor.
• Grapefruit Juice: Avoid consuming grapefruit juice as it may increase the absorption of the medicine and lead to side effects.

What happens if a dose of FIBRODONE 200 MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should FIBRODONE 200 MG TAB be stored?

Store the medicine in a closed container at room temperature (below 30°C or 25°C), away from heat, moisture, and direct sunlight. Keep it out of the reach of children and pets. Do not keep outdated medicine and ask your pharmacist how to dispose of unused medicine.