Vysov M 50/1000 Mg 15 Tab

VYSOV M 50/1000 MG 15 TAB by CIPLA HEALTH LTD

Name

Brand Name: VYSOV M 50/1000 MG TABLET Common Names: Vildagliptin and Metformin Hydrochloride

Composition

VYSOV M 50/1000 MG Tablet contains two active ingredients:

• Vildagliptin: 50 mg
• Metformin Hydrochloride: 1000 mg

Uses

VYSOV M 50/1000 MG Tablet is prescribed for the management of Type 2 Diabetes Mellitus in adults. It is used to improve blood sugar control as an adjunct to diet and exercise, especially when blood sugar levels are not adequately controlled by either metformin or vildagliptin alone, or with other diabetes medicines. This medication helps prevent serious complications associated with diabetes, such as kidney damage, blindness, nerve problems, limb amputations, and cardiovascular events.

Dosage and Administration

VYSOV M 50/1000 MG Tablet should be taken orally as directed by your doctor. It is typically consumed with meals to minimize gastrointestinal discomfort. Swallow the tablet whole with a glass of water; do not crush or chew it. The dosage and frequency (often once or twice daily) will vary based on your medical condition, blood sugar levels, and any other medications you are taking. Adhere strictly to the prescribed dose and schedule, and do not discontinue the medication without consulting your doctor.

Side Effects

Common Side Effects:

• Diarrhea
• Stomach pain / Abdominal discomfort
• Nausea and Vomiting
• Loss of appetite
• Metallic taste
• Low blood glucose (hypoglycemia), especially when used with insulin or sulfonylureas
• Joint pain, tiredness, fatigue
• Constipation
• Headache, dizziness
• Swollen hands, ankles, or feet (oedema)

Serious Side Effects (Rare):

• Lactic acidosis: Symptoms include vomiting, stomach pain, decreased heartbeat, difficulty breathing, muscle cramps, general weakness with severe tiredness, or reduced body temperature. Seek immediate medical attention if these occur.
• Inflamed pancreas (pancreatitis): Characterized by severe and persistent pain in the abdomen, with or without nausea or vomiting.
• Liver dysfunction.

Precautions

• Contraindications: Do not use VYSOV M if you have a known allergy to vildagliptin, metformin, or any other components of the tablet. It is also contraindicated in patients with Type 1 Diabetes Mellitus, severe kidney or liver disease, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
• Pregnancy and Breastfeeding: VYSOV M is not generally recommended for pregnant or breastfeeding women. Consult your doctor for advice if you are pregnant, planning a pregnancy, or breastfeeding.
• Alcohol Consumption: Avoid excessive alcohol consumption as it may increase the risk of lactic acidosis.
• Kidney and Liver Impairment: Patients with kidney or liver problems should use this medication with caution and require regular monitoring and potential dose adjustments by a doctor.
• Elderly Patients: Use with caution in elderly patients (65 years and above), especially those with impaired kidney function.
• Pediatric Use: This medicine is not suitable for use in children and adolescents under 18 years of age.
• Driving and Operating Machinery: If you experience dizziness or low blood sugar, your ability to drive or operate machinery may be affected. Exercise caution.
• Surgery: Inform your doctor if you are scheduled for surgery, as discontinuation of the medicine might be advised due to the increased risk of lactic acidosis.
• Drug Interactions: Inform your doctor about all other medicines, supplements, or herbal products you are taking to prevent potential interactions.

Storage

Store VYSOV M 50/1000 MG tablets in a cool and dry place, protected from direct sunlight, moisture, and heat. The ideal storage temperature is typically between 15-30°C or below 30°C. Keep the medicine out of the sight and reach of children and pets. Ensure to use the tablets before their expiry date and discard any unused medicine properly.

VYSOV M 50/1000 MG is a medication used to manage Type 2 Diabetes Mellitus. It combines two active ingredients: Vildagliptin (50 mg) and Metformin (1000 mg).

What is VYSOV M 50/1000 MG used for?

VYSOV M 50/1000 MG is primarily used to manage high blood sugar levels in adult patients with Type 2 Diabetes Mellitus. It is prescribed when diet and exercise alone, or treatment with either metformin or vildagliptin alone, are not sufficient to control blood sugar. This medication helps improve overall blood sugar control and can reduce the risk of serious complications associated with diabetes, such as kidney damage, blindness, nerve problems, limb amputations, and cardiovascular events like heart attacks and strokes.

How does VYSOV M 50/1000 MG work?

VYSOV M 50/1000 MG works through the combined action of its two components:

• Vildagliptin (50 mg): This is a DPP-4 inhibitor that works by increasing the release of insulin from the pancreas in a glucose-dependent manner (meaning it acts when blood glucose levels are high). It also decreases the secretion of glucagon, a hormone that raises blood glucose levels.
• Metformin (1000 mg): This belongs to a class of medications called biguanides. It primarily reduces glucose production by the liver, decreases the absorption of glucose from the intestines, and enhances the body's sensitivity to insulin. Together, these actions lead to better control of both fasting and post-meal blood sugar levels.

What is the usual dosage of VYSOV M 50/1000 MG?

The dosage of VYSOV M 50/1000 MG should be taken exactly as advised by your doctor, as it depends on your specific health condition, blood sugar levels, and response to treatment. Generally, tablets should be swallowed whole with a glass of water, preferably with meals, to reduce stomach upset. Do not crush, chew, or split the tablet. Do not change your dose or stop taking the medicine without consulting your doctor.

What are the possible side effects of VYSOV M 50/1000 MG?

Common side effects may include headache, dizziness, nausea, vomiting, diarrhea, stomach pain, fatigue, constipation, loss of appetite, metallic taste, joint pain, and low blood pressure.

More serious but rare side effects can include:

• Lactic Acidosis: Symptoms may include persistent nausea, vomiting, stomach pain, decreased heartbeat, difficulty breathing, muscle cramps, general weakness with severe tiredness, or reduced body temperature.
• Hypoglycemia (low blood sugar): This can occur, especially if taken with other antidiabetic medicines, or if there is insufficient calorie intake, missed meals, excessive alcohol consumption, or over-exercise. Symptoms include dizziness, sweating, palpitations, hunger pangs, and confusion. Consult your doctor if any side effects persist or worsen.

Is VYSOV M 50/1000 MG safe during pregnancy or breastfeeding?

VYSOV M 50/1000 MG is generally not recommended during pregnancy, and caution is advised. Limited information is available regarding its safety, and animal studies have shown potential harmful effects on the developing baby. It is also not recommended for breastfeeding women, as its components are known to pass into breast milk and may harm the baby. Always consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Can VYSOV M 50/1000 MG be taken with other medications?

VYSOV M 50/1000 MG can interact with certain medications. It is crucial to inform your doctor about all medicines, supplements, or herbal products you are currently taking or plan to take. Potential interactions include:

• Cationic medications: Such as amiloride, digoxin, and morphine, which share renal tubular transport systems with metformin.
• Carbonic anhydrase inhibitors: Like topiramate, which may increase the risk of lactic acidosis.
• Hyperglycemic medications: Glucocorticoids, beta-2-agonists, and diuretics can counteract the blood sugar-lowering effect.
• ACE-inhibitors: Medicines like benazepril, captopril, and enalapril could cause hypoglycemia.
• Painkillers: Such as aspirin, ibuprofen, and celecoxib.
• Antacids: Like cimetidine.
• Thyroid hormones: Such as thyroxine.

What precautions should be taken with VYSOV M 50/1000 MG?

• Alcohol: Avoid chronic excessive alcohol consumption, as it can significantly increase the risk of lactic acidosis and affect blood sugar control.
• Kidney and Liver Conditions: This medicine is contraindicated in severe renal disease or end-stage renal disease requiring dialysis due to the risk of metformin accumulation. Caution is also advised if you have liver problems, and its safety and efficacy haven't been established in patients with impaired hepatic function.
• Heart Conditions: Caution is needed in patients at risk for lactic acidosis, such as those with congestive heart failure.
• Children: VYSOV M 50/1000 MG is not recommended for use in children under 18 years of age.
• Elderly Patients: Use with caution and under medical supervision, as older patients may be more susceptible to side effects.
• Surgery: Inform your doctor if you are scheduled for surgery, as they may advise you to discontinue the medication temporarily.
• Allergies: Do not take this medicine if you have a known hypersensitivity to metformin, vildagliptin, or any of its ingredients.
• Diet and Exercise: It is crucial to continue following a balanced diet and regular exercise routine as recommended by your doctor to achieve the best results from the medication.

What happens if a dose of VYSOV M 50/1000 MG is missed?

If you forget to take a dose, take it as soon as you remember. However, if it's nearly time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should VYSOV M 50/1000 MG be stored?

Store VYSOV M 50/1000 MG at a temperature not exceeding 30°C. Keep it in its original container or package, securely sealed, and protect it from moisture, direct light, and heat. Always keep the medicine out of the reach of children. Ensure you use the medication before its expiry date.