Ozotel Amh Tablet (30 Tab)

OZOTEL AMH TABLET

OZOTEL AMH TABLET, manufactured by Ozone Pharmaceuticals Ltd., is a combination medication prescribed for the management of hypertension.

• Composition: Each tablet contains Telmisartan (40mg), Amlodipine (5mg), and Hydrochlorothiazide (12.5mg). Telmisartan is an angiotensin receptor blocker, Amlodipine is a calcium channel blocker, and Hydrochlorothiazide is a diuretic. These ingredients work synergistically to relax and widen blood vessels, improve blood flow, and increase the excretion of excess water and salts from the body.

• Uses: This medicine is primarily used for the treatment of hypertension (high blood pressure), especially when blood pressure is not adequately controlled by dual therapy. It helps reduce the risk of future cardiovascular events such as heart attack and stroke.

• Dosage and Administration: The typical dosage is one tablet once daily, as advised by your doctor. It can be taken with or without food but should be swallowed whole with water; do not chew, crush, or break the tablet. To avoid increased urination during the night, it is advisable not to take this medicine within four hours of bedtime.

• Side Effects:

  • Common: Dizziness, headache, fatigue, ankle swelling (peripheral edema), taste changes, muscle weakness, dry mouth, and extreme thirst.
  • Serious (consult doctor immediately): Allergic reactions (rash, swelling of face/throat), severe dizziness, difficulty breathing, low blood pressure (fainting), or electrolyte imbalances.

• Precautions:

  • Pregnancy and Breastfeeding: OZOTEL AMH TABLET is not recommended during pregnancy due to definite evidence of risk to the developing baby and is unsafe during breastfeeding.
  • Alcohol: Avoid alcohol consumption as it may enhance the blood pressure-lowering effect and increase dizziness.
  • Liver/Kidney Conditions: Use with caution in patients with liver or severe kidney disease, as dose adjustments may be necessary.
  • Driving: May cause drowsiness, which could affect the ability to drive or operate machinery.
  • Hydration: Drink plenty of fluids to manage potential dry mouth and thirst caused by the diuretic component.
  • Do not discontinue the medication abruptly without consulting your doctor.

• Storage: Store in a cool and dry place, protected from moisture and direct sunlight, typically below 30°C. Keep out of the sight and reach of children.

Here are the most frequently asked questions about Ozotel AMH Tablet:

What is Ozotel AMH Tablet used for?

Ozotel AMH Tablet is a combination medication primarily used for the management of hypertension, also known as high blood pressure. It is often prescribed when a single medication is insufficient to control blood pressure levels. By effectively lowering high blood pressure, it helps reduce the risk of serious complications such as heart attack, stroke, and kidney damage. It may also be used in cases of heart failure symptoms and edema (fluid retention).

How does Ozotel AMH Tablet work?

Ozotel AMH Tablet contains three active ingredients: Telmisartan, Amlodipine, and Hydrochlorothiazide.

• Telmisartan is an angiotensin receptor blocker (ARB) that works by blocking the action of certain substances responsible for tightening blood vessels. This allows blood to flow more smoothly and makes the heart more efficient at pumping blood throughout the body.
• Amlodipine is a calcium channel blocker that relaxes and widens blood vessels by preventing calcium from entering the smooth muscle cells of the heart and blood vessels, thereby improving blood flow.
• Hydrochlorothiazide is a diuretic (water pill) that helps the kidneys remove extra water and certain electrolytes, like salt, from the body through urine. This reduces fluid buildup and further lowers blood pressure.

What is the usual dosage of Ozotel AMH Tablet?

The usual dosage of Ozotel AMH Tablet is typically one tablet per day. However, the exact dose and duration of treatment will be determined by your doctor based on your medical condition and how you respond to the medication. It is important to swallow the tablet whole with a glass of water and not to chew, bite, or break it. It can be taken with or without food, but it is recommended to take it at the same time each day for maximum effectiveness.

What are the possible side effects of Ozotel AMH Tablet?

Common side effects of Ozotel AMH Tablet may include ankle swelling, headache, dizziness, fatigue, taste changes, muscle weakness, dry mouth, extreme thirst, flu-like symptoms, diarrhea, and sinusitis. Most of these side effects are temporary and usually resolve over time. If side effects persist, worsen, or become bothersome, it is recommended to consult your doctor. Seek immediate medical attention if you experience severe symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain, rapid heartbeat, memory loss, severe allergic reactions, low potassium levels, or sudden swelling.

Is Ozotel AMH Tablet safe during pregnancy or breastfeeding?

Ozotel AMH Tablet is generally not recommended and is considered unsafe for use during pregnancy, especially in the second and third trimesters, as it may cause harm to the developing baby. Telmisartan, one of the components, has been associated with fetal toxicity. If you are pregnant or planning to become pregnant, inform your doctor immediately, as safer alternatives for blood pressure management will be needed.

Ozotel AMH Tablet is also not recommended during breastfeeding. Components of the medicine pass into breast milk and may cause harm to the nursing infant. Your doctor may suggest an alternative medication, especially if you are breastfeeding a newborn or premature baby.

Can Ozotel AMH Tablet be taken with other medications?

Yes, Ozotel AMH Tablet can interact with various medications. It is crucial to inform your doctor about all medications you are taking, including over-the-counter medicines, herbal supplements, and vitamins, to avoid harmful drug interactions.

Some notable interactions include:

• Other antihypertensive drugs: Can enhance blood pressure-lowering effects, increasing the risk of hypotension (low blood pressure).
• NSAIDs (nonsteroidal anti-inflammatory drugs) like ibuprofen or naproxen: Can reduce the blood pressure-lowering effect of Ozotel AMH Tablet and increase the risk of kidney problems.
• Potassium-containing salt substitutes or potassium supplements: Should be avoided as they can cause high levels of potassium in your blood.
• Antidiabetic medications (e.g., metformin, insulin): Dosage adjustments may be needed as Ozotel AMH Tablet can affect glucose tolerance.
• Lithium: May increase the risk of lithium toxicity, requiring close monitoring of blood levels.
• Corticosteroids: Can enhance electrolyte depletion, particularly lowering potassium levels.
• Idelalisib and Tizanidine: Co-administration may lead to serious side effects and requires careful monitoring.

Additionally, avoid consuming grapefruit and grapefruit juice as they can interact with amlodipine and increase the risk of side effects like low blood pressure and dizziness.

What precautions should be taken while using Ozotel AMH Tablet?

Several precautions should be taken while using Ozotel AMH Tablet:

• Alcohol: Avoid consuming alcohol as it may enhance the blood pressure-lowering effect and increase the risk of dizziness, headache, and fainting.
• Liver and Kidney Issues: Inform your doctor if you have any liver or kidney problems. Ozotel AMH Tablet is not recommended for patients with severe liver disease or severe kidney disease and anuria (low urine output). Caution is advised in patients with mild liver or kidney impairment.
• Driving and Operating Machinery: This medicine may cause dizziness, headaches, or tiredness, which can affect your ability to drive or operate machinery. It is advised to avoid such activities until you know how the medicine affects you.
• Dehydration: The diuretic component (hydrochlorothiazide) can lead to increased urination and dehydration. Drink plenty of fluids to overcome dry mouth and extreme thirst. Inform your doctor if symptoms of dehydration persist.
• Bedtime Dosing: Due to its diuretic effect, avoid taking this medicine within four hours of bedtime to prevent excessive urination at night and sleep disturbances.
• Monitoring: Regular monitoring of blood pressure, kidney function, electrolyte levels, and blood sugar levels is essential to ensure the medication is working effectively and safely.
• Low-Salt Diet: If you are on a low-salt diet, discuss this with your doctor.
• Children and Elderly: Ozotel AMH Tablet is not recommended for use in children below 18 years of age. Older patients should take it under medical supervision as they may be more susceptible to side effects.
• Sudden Discontinuation: Do not stop taking Ozotel AMH Tablet without consulting your doctor, as sudden discontinuation can cause blood pressure to rise significantly, increasing the risk of heart attack or stroke. Your doctor may gradually reduce your dose.

What happens if a dose of Ozotel AMH Tablet is missed?

If you miss a dose of Ozotel AMH Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Consistent adherence is key to managing high blood pressure effectively.

How should Ozotel AMH Tablet be stored?

Ozotel AMH Tablet should be stored at room temperature, protected from moisture and heat. Keep it in the packet or container it came in, tightly closed, and away from direct sunlight. Ensure it is kept out of the reach and sight of children and pets. Dispose of any unused medicine responsibly.