Onarni 200mg Tab

ONARNI 200MG Tablet

Name

• Brand Name: ONARNI 200MG Tablet
• Common Name: Sacubitril/Valsartan 200mg (Combination of Sacubitril 97mg + Valsartan 103mg)

Composition ONARNI 200MG Tablet is a fixed-dose combination medication containing:

• Sacubitril (97 mg)
• Valsartan (103 mg)

Uses ONARNI 200MG Tablet is primarily used for the treatment of heart failure. It helps reduce the risk of hospitalization and death in adults and children above one year of age with chronic heart failure, particularly heart failure with reduced ejection fraction. It works by relaxing and widening blood vessels, making it easier for the heart to pump blood, and also aids in managing hypertension and providing cardiovascular protection.

Dosage and Administration Take ONARNI 200MG Tablet exactly as prescribed by your doctor. It is usually taken orally, twice daily, with or without food. The tablet should be swallowed whole; do not chew, crush, or break it. Do not stop taking the medicine suddenly, even if you feel well, as this may worsen your condition.

Side Effects Common side effects may include:

• Cough
• Dizziness, light-headedness
• Nausea, diarrhea, weakness, fatigue
• Low blood pressure (hypotension)
• Impaired renal function
• High potassium levels in the blood (hyperkalemia)
• Headache

Precautions

• Avoid taking ONARNI 200MG Tablet if you are allergic to its components.
• Do not take it with ACE inhibitors; a washout period of at least 36 hours is required before or after taking an ACE inhibitor.
• Inform your doctor if you have kidney or liver diseases, diabetes (especially if taking aliskiren), or a history of angioedema.
• Not recommended during pregnancy or breastfeeding due to potential risks to the baby.
• May cause orthostatic hypotension; rise slowly from sitting or lying positions.
• Avoid alcohol consumption as it may interact with the medication.
• Regular monitoring of blood pressure, kidney function, and potassium levels is advised.

Storage Store in a cool and dry place, away from direct sunlight. Keep out of the sight and reach of children. Store at room temperature, typically between 10ºC to 25ºC or below 30ºC, and protect from moisture and heat.

ONARNI 200MG TAB: Frequently Asked Questions

ONARNI 200MG TAB is a prescription medication primarily used in the management of heart failure. Here are some frequently asked questions about this medicine.

What is ONARNI 200MG TAB used for?

ONARNI 200MG TAB is used to treat heart failure, particularly in adults and children (aged 1 year and older) with chronic heart failure that has a reduced ejection fraction. It helps to reduce the risk of hospitalization and death in these patients by making the heart pump blood more efficiently. It may also be used for hypertension management and cardiovascular protection by lowering blood pressure, reducing the risk of heart attacks and strokes.

How does ONARNI 200MG TAB work?

ONARNI 200MG TAB is a combination of two medicines: sacubitril and valsartan. Sacubitril is a neprilysin inhibitor, which works by relaxing and widening blood vessels, reducing fluid buildup, and lowering blood pressure by preventing the breakdown of natural substances (natriuretic peptides) in the body. Valsartan is an angiotensin receptor blocker (ARB) that blocks the effects of angiotensin II, a hormone that narrows blood vessels and increases blood pressure. Together, these components help relax and widen blood vessels, making it easier for the heart to pump blood throughout the body and reducing strain on the heart.

What is the usual dosage for ONARNI 200MG TAB?

The dosage of ONARNI 200MG TAB is determined by your doctor and depends on your specific medical condition and response to treatment. It is typically taken orally, with or without food, and usually twice daily. It is crucial to take the tablets regularly as prescribed and not to exceed the recommended dose.

What are the possible side effects of ONARNI 200MG TAB?

Common side effects of ONARNI 200MG TAB can include dizziness, low blood pressure (hypotension), cough, increased potassium levels in the blood (hyperkalemia), impaired kidney function, nausea, diarrhea, and weakness. Less common side effects might include headache and fatigue. If side effects are persistent or severe, it is advisable to consult your doctor.

Is ONARNI 200MG TAB safe during pregnancy or breastfeeding?

No, ONARNI 200MG TAB is generally not recommended during pregnancy and is considered unsafe, especially after the first three months, as it can harm the developing baby. It is also not recommended for use while breastfeeding. You should consult your doctor for alternative treatment options if you are pregnant, planning to become pregnant, or breastfeeding.

Can ONARNI 200MG TAB be taken with other medications?

ONARNI 200MG TAB can interact with several other medications. It should not be taken with ACE inhibitors (e.g., captopril or enalapril) and there should be a gap of at least 36 hours before or after taking an ACE inhibitor. Concomitant use with potassium-sparing diuretics (e.g., spironolactone) or potassium supplements can increase blood potassium levels. Non-steroidal anti-inflammatory drugs (NSAIDs) can worsen kidney function when taken with ONARNI 200MG TAB. It should also be avoided if you have diabetes and are taking aliskiren-containing blood pressure-lowering medicine. Always inform your doctor about all medications, herbal preparations, and supplements you are currently taking to avoid potential drug interactions.

What precautions should be taken while taking ONARNI 200MG TAB?

Inform your doctor if you are allergic to sacubitril, valsartan, or any other components of the tablet. Exercise caution if you have kidney or liver diseases, low blood pressure, diabetes, or a history of angioedema (rapid swelling under the skin). Dizziness may occur, so rise slowly from sitting or lying positions. Alcohol consumption should generally be avoided while taking this medicine as it may interact and lead to adverse effects. Regular monitoring of blood pressure and kidney function may be advised by your doctor.

What happens if a dose of ONARNI 200MG TAB is missed?

If you miss a dose of ONARNI 200MG TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should ONARNI 200MG TAB be stored?

ONARNI 200MG TAB should be stored in a cool and dry place, away from direct sunlight. Keep it out of the sight and reach of children. The recommended storage temperature is typically between 10ºC to 25ºC or below 30ºC.