Pilorute Cream 30 Gm

PILORUTE CREAM 30 GM

Pilorute Cream 30 GM is a topical medication manufactured by Mankind Pharma Ltd., formulated to alleviate the symptoms associated with anorectal conditions such as hemorrhoids (piles) and anal fissures. It provides a multi-faceted approach to reduce pain, inflammation, itching, and discomfort, while also promoting healing in the affected area.

Composition

Pilorute Cream contains a combination of six active ingredients:

• Calcium Dobesilate (0.25% w/w): A vasoprotective agent that strengthens blood vessel walls, reduces permeability, and helps decrease swelling and fluid leakage.
• Hydrocortisone (0.25% w/w): A corticosteroid that reduces itching, redness, and swelling due to its anti-inflammatory properties.
• Lidocaine / Lignocaine (3% w/w): A local anesthetic that blocks pain signals from nerves, providing rapid relief from pain and itching.
• Phenylephrine (0.1% w/w): A decongestant and vasoconstrictor that shrinks swollen blood vessels, thereby decreasing irritation and discomfort.
• Troxerutin (2% w/w): Another vasoprotective agent that improves blood circulation, strengthens blood vessels, and helps reduce inflammation, swelling, and pain.
• Zinc Oxide (5% w/w): Possesses antiseptic, astringent, and protective properties, promoting tissue healing and reducing irritation.

Uses

Pilorute Cream is prescribed for the treatment of:

• Hemorrhoids (Piles): Alleviates pain, swelling, itching, and discomfort caused by inflamed and swollen veins in the rectum and anus.
• Anal Fissures: Promotes healing, reduces pain, and lessens inflammation associated with small tears in the lining of the anus.
• Proctitis and other inflammatory anorectal conditions: Helps in managing symptoms of inflammation of the rectum and surrounding tissues.
• Post-surgical discomfort: Provides relief from pain and discomfort following surgery in the anal region.
• Perianal Itching and Irritation: Effective in relieving itching, burning, and irritation in the anal area.

Dosage and Administration

Pilorute Cream is for external use only.

• Clean and dry the affected rectal area thoroughly before application.
• Wash hands before and after applying the cream.
• Apply a pea-sized amount onto the affected area, using the provided applicator if necessary, directly onto the rectal area.
• Use in the dose and duration as advised by a healthcare professional. Do not exceed the prescribed dose or duration.

Side Effects

Common side effects may include:

• Burning sensation at the application site.
• Irritation.
• Itching.
• Redness.

These side effects are usually temporary and resolve over time. However, if they persist or worsen, consult a doctor. Rare cases of allergic reactions (redness, itching, swelling, difficulty breathing) may occur; discontinue use and seek medical attention if experienced.

Precautions

• Do not use Pilorute Cream if allergic to any of its components or if there has been a skin reaction to any steroid medicine.
• Consult a doctor before use if pregnant or breastfeeding.
• Avoid contact with eyes, nose, or mouth. In case of accidental exposure, rinse with water and seek immediate medical attention.
• Do not use for longer durations than prescribed by a doctor (typically not more than 2-4 weeks).
• Do not apply over a large area or use with tight-fitting dressings/diapers unless directed by a doctor.
• Inform the doctor about any pre-existing medical conditions or other medications being taken to prevent potential interactions.
• Discontinue use and inform your doctor if the condition worsens or if increased redness and irritation develop.

Storage

Store Pilorute Cream in a cool, dry place, away from heat, light, and moisture. Keep out of reach of children and pets. Do not use after the expiration date printed on the package.

Here are the most frequently asked questions about Pilorute Cream 30 GM:

What is Pilorute Cream 30 GM used for?

Pilorute Cream 30 GM is a combination medicine primarily used to treat hemorrhoids (piles) and anal fissures. It helps alleviate associated symptoms such as pain, swelling, itching, burning, and discomfort in the anal area. It may also be used for proctitis, painful bowel movements, and discomfort following hemorrhoid removal surgery.

How does Pilorute Cream 30 GM work?

Pilorute Cream works through a combination of active ingredients:

• Lidocaine (Lignocaine): A local anesthetic that blocks nerve pain signals, providing pain relief.
• Hydrocortisone: A corticosteroid that reduces inflammation, itching, redness, and swelling.
• Phenylephrine: A decongestant and vasoconstrictor that shrinks swollen blood vessels, thereby reducing irritation, discomfort, and swelling.
• Zinc Oxide: Acts as an antiseptic and astringent, forming a protective barrier on the skin, promoting healing, and providing a soothing effect.
• Calcium Dobesilate & Troxerutin: These are vasoprotective agents that strengthen blood vessels, improve blood circulation, reduce inflammation, and decrease leakage from blood vessels, aiding in healing.

What is the usual dosage for Pilorute Cream 30 GM?

Generally, a thin layer of Pilorute Cream 30 GM is applied to the affected anal area two to three times daily, or as directed by your doctor. It is important to thoroughly cleanse and dry the affected area before application. You should follow your physician's instructions regarding the frequency and duration of use.

What are the possible side effects of Pilorute Cream 30 GM?

Common side effects at the application site include burning, irritation, redness, and itchiness. These reactions are usually temporary and may subside over time. If these symptoms persist, worsen, or if you experience more severe side effects such as constipation, increased sensitivity, infection, or signs of methemoglobinemia (e.g., pale, gray, or blue skin, headache, rapid heartbeat), discontinue use and seek immediate medical attention.

Is Pilorute Cream 30 GM safe during pregnancy or breastfeeding?

During pregnancy, Pilorute Cream should only be used if clearly necessary and under the guidance of a doctor, as safety and effectiveness are not fully established. For breastfeeding women, it should be used with caution, and consultation with a doctor is recommended.

Can Pilorute Cream 30 GM be taken with other medications?

While drug interactions are generally unlikely with topical application, it is important to inform your doctor about all medications you are currently taking, including other topical products, herbal supplements, and over-the-counter medicines. Caution is advised if you are taking blood thinners (e.g., Warfarin, Heparin) or other local anesthetics, as some interactions may be possible.

What precautions should be taken while using Pilorute Cream 30 GM?

Avoid getting the cream into your eyes, nose, or mouth. If accidental contact occurs, rinse thoroughly with water and seek medical attention if irritation persists. Pilorute Cream is not recommended for children under 12 years of age. It should be used with caution in patients with lung, liver, or heart problems. Do not use the cream if you are allergic to any of its ingredients or if you have specific infections like tuberculous, fungal lesions, varicella (chickenpox), or acute herpes simplex infection in the application area.

What happens if a dose of Pilorute Cream 30 GM is missed?

If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one.

How should Pilorute Cream 30 GM be stored?

Pilorute Cream should be stored below 25°C or at room temperature, away from direct heat, light, and moisture. Keep it out of the reach of children and pets. Do not use the cream after its expiration date.