Anti Thyrox 10 Mg Tablet (100 Tab)

ANTI THYROX 10 MG TABLET (100 TAB) by MACLEODS PHARMACEUTICALS LTD.

Name:

• Brand Name: Anti Thyrox 10 mg Tablet
• Common Name: Carbimazole (as the active ingredient)

Composition:

• Each tablet contains Carbimazole 10 mg.

Uses: Anti Thyrox 10 mg Tablet is primarily used for the management of hyperthyroidism, a condition where the thyroid gland produces excessive thyroid hormones. It helps to reduce the overproduction of these hormones and alleviate associated symptoms such as unexplained weight loss, rapid heartbeat, nervousness, irritability, tremors, excessive sweating, and heat intolerance. This medication is also utilized to restore normal thyroid function before partial surgical removal of the thyroid gland (thyroidectomy) or before and after radioactive iodine treatment.

Dosage and Administration: Anti Thyrox 10 mg Tablet should be taken orally as prescribed by a doctor. The tablet should be swallowed whole with a glass of water, without crushing or chewing. It can be taken with or without food, but taking it consistently at the same time each day is recommended for optimal results. Initial adult dosage for hyperthyroidism typically ranges from 20-60 mg daily, which is gradually reduced once euthyroidism (normal thyroid function) is achieved. Maintenance dosage is usually 5-15 mg daily for at least 1-1.5 years. The dosage may vary based on the patient's condition and response to treatment.

Side Effects: Common side effects may include:

• Nausea, Vomiting
• Headache
• Joint pain
• Skin rashes, Itching
• Fever
• Changes in taste sensation
• Gastrointestinal disturbance
• Hair loss
• Drowsiness

Serious side effects, though rare, can include:

• Agranulocytosis (severe reduction in white blood cells), which can manifest as sore throat, mouth ulcers, or fever
• Liver problems, such as jaundice (yellowing of skin and eyes), abdominal pain, dark urine, or loss of appetite
• Acute pancreatitis (inflammation of the pancreas)
• Bone marrow toxicity

Precautions:

• Inform your doctor if you have severe liver disorders, serious blood disorders, or a history of acute pancreatitis, as this medicine is not recommended in these conditions.
• Use with caution in pregnant women, as it can harm the unborn baby, and effective contraceptive measures are recommended during treatment.
• Avoid during breastfeeding as it may pass into breast milk.
• Regular monitoring of thyroid levels and blood cell counts is necessary during treatment.
• Inform your doctor about all current medications, including supplements and herbal products, to avoid potential drug interactions (e.g., with anticoagulants, theophylline, steroids, antibiotics, digitalis, beta-blockers).
• If symptoms like unexplained bruising, bleeding, sore throat, mouth ulcers, fever, or signs of liver damage occur, discontinue the medicine and seek immediate medical advice.
• Not recommended for children below 2 years of age.
• May cause dizziness; exercise caution while driving or operating machinery.

Storage: Store Anti Thyrox 10 mg Tablets at room temperature in a clean and dry place, protected from moisture, sunlight, and heat. Keep out of reach of children and pets.

What is Anti Thyrox 10 MG Tablet used for?

Anti Thyrox 10 MG Tablet is primarily used to manage hyperthyroidism, a condition where the thyroid gland produces an excessive amount of thyroid hormones. It helps to reduce these hormone levels and alleviate associated symptoms such as unexplained weight loss, rapid heartbeat, nervousness, irritability, tremors, excessive sweating, and heat intolerance. This medicine may also be used before thyroid gland removal surgery (thyroidectomy) or before and after radioactive iodine treatment for hyperthyroidism and thyroid cancer.

How does Anti Thyrox 10 MG Tablet work?

Anti Thyrox 10 MG Tablet contains Carbimazole, which is a prodrug that is rapidly converted to its active form, thiamazole (also known as methimazole), in the body. It works by interfering with the incorporation of iodine into tyrosine residues, a crucial step in the synthesis of thyroid hormones (T3 and T4) in the thyroid gland. By doing so, it effectively reduces the production of these excessive thyroid hormones, helping to restore normal thyroid function.

What is the usual dosage of Anti Thyrox 10 MG Tablet?

The dosage of Anti Thyrox 10 MG Tablet is determined by your doctor based on your health condition and response to the medicine. For adults with hyperthyroidism, an initial dose may range from 20-60 mg daily, taken as a single or divided dose. This is gradually reduced once normal thyroid function is achieved, typically to a maintenance dose of 5-15 mg daily for at least one year or 18 months. It is crucial to follow your doctor's instructions precisely and never alter the dosage without their advice. The tablet should be swallowed whole with a glass of water and not crushed or chewed.

What are the possible side effects of Anti Thyrox 10 MG Tablet?

Common side effects can include nausea, vomiting, headache, fever, joint pain, itching, skin rashes, and changes in taste sensation. More serious, but rare, side effects can include agranulocytosis (a severe reduction in white blood cells), liver problems (such as jaundice, abdominal pain, dark urine, or yellowing of the eyes or skin), and acute pancreatitis (inflammation of the pancreas). If you experience any severe or persistent side effects, or symptoms like unexplained bruising or bleeding, sore throat, or mouth ulcers, you should contact your doctor immediately.

Is Anti Thyrox 10 MG Tablet safe during pregnancy or breastfeeding?

Pregnancy: Anti Thyrox 10 MG Tablet should be used during pregnancy only if the benefits significantly outweigh the potential risks, as it may cause abnormalities in the baby. Untreated hyperthyroidism during pregnancy can also increase the chances of birth defects. Women of childbearing age should use effective contraception while on this medication. Your doctor will weigh the risks and benefits and may prescribe the lowest possible dose if necessary.

Breastfeeding: Caution is advised during breastfeeding as Carbimazole, the active ingredient, may pass into breast milk. While some studies suggest it reaches sub-clinical levels in infants at doses less than 30 mg/day, monitoring the infant's thyroid function may be recommended. It is generally advised to discuss potential risks and benefits with your doctor before using this medicine while breastfeeding.

Can Anti Thyrox 10 MG Tablet be taken with other medications?

Anti Thyrox 10 MG Tablet can interact with several other medications. For example, it may reduce the effectiveness of oral anticoagulants like warfarin, and increase the levels of asthma medications (like theophylline), steroids (like prednisolone), and certain antibiotics (like erythromycin). Heart medications such as digoxin and beta-blockers (like propranolol and atenolol) may also have altered effects when taken with Anti Thyrox 10 MG Tablet, requiring dose adjustments. Always inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid possible interactions.

What precautions should be taken while taking Anti Thyrox 10 MG Tablet?

Several precautions should be observed when taking Anti Thyrox 10 MG Tablet. It is not recommended for patients with severe liver disorders or blood dyscrasias. If you have a history of kidney problems or bone marrow suppression, caution is advised. You should also avoid this medicine if you have developed acute pancreatitis after previous treatment with Carbimazole. If you experience symptoms such as a sore throat, mouth ulcers, fever, unexplained bruising or bleeding, or signs of liver damage (like jaundice, abdominal pain, dark urine), contact your doctor immediately. You may need to temporarily stop this medication if you are undergoing radio-iodine treatment.

What happens if a dose of Anti Thyrox 10 MG Tablet is missed?

If you miss a dose of Anti Thyrox 10 MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. Regular monitoring of your thyroid hormone levels is essential, especially if doses are missed frequently.

How should Anti Thyrox 10 MG Tablet be stored?

Anti Thyrox 10 MG Tablet should be stored at room temperature in a clean, dry place. It should be protected from moisture, sunlight, and heat. Always keep the medicine out of the reach and sight of children and pets.