Thyroup 100

THYROUP 100 Tablet

THYROUP 100 Tablet, manufactured by LUPIN LTD, is a medication primarily used for thyroid hormone replacement therapy.

• Name:

  • Brand Name: THYROUP 100 Tablet
  • Common Name: Levothyroxine Sodium (Thyroxine)

• Composition:

  • Each tablet contains 100 mcg (0.1 mg) of Levothyroxine sodium, a synthetic form of the naturally occurring thyroid hormone thyroxine (T4).

• Uses: THYROUP 100 is prescribed for various conditions related to thyroid hormone deficiency.

  • Hypothyroidism: It is primarily used to treat an underactive thyroid gland, where the thyroid does not produce sufficient thyroid hormones.
  • Goitre: Management of an enlarged thyroid gland.
  • Thyroid Cancer: Used in the management of certain types of thyroid cancer.
  • Myxedema Coma: In some cases, it may be used to treat this severe complication of hypothyroidism.
  • Diagnosis: May be used by doctors to test for hyperthyroidism.

• Dosage and Administration:

  • THYROUP 100 Tablet should be taken orally once daily on an empty stomach, ideally in the morning, at least 30-60 minutes before breakfast.
  • Swallow the tablet whole with a glass of water; do not crush or chew.
  • The dosage is individualized by a doctor based on the patient's age, weight, medical history, and thyroid function tests.
  • It is crucial to take the medicine at the same time every day for optimal results and to maintain stable hormone levels.
  • Do not discontinue or alter the dose without consulting a doctor.

• Side Effects: Common side effects may include:

  • Headache
  • Nervousness, irritability, restlessness
  • Trouble falling asleep or staying asleep (insomnia)
  • Increased sweating, heat intolerance
  • Appetite changes, weight loss
  • Tremors or shaking of hands and feet
  • Diarrhea, abdominal cramps
  • Changes in menstrual cycle (in women)

  Serious side effects, though rare, can occur:

  • Chest pain, irregular or fast heartbeat, palpitations
  • Shortness of breath
  • Severe dizziness or fainting
  • Allergic reactions (rash, itching, swelling)
  • Very high temperature, confusion, fits (in overdose)

• Precautions:

  • Inform your doctor about any pre-existing medical conditions, especially heart disease, high blood pressure, diabetes, adrenal or pituitary gland problems, and osteoporosis, as THYROUP 100 may interact with these conditions.
  • Caution is advised in patients with kidney or liver problems.
  • Pregnancy and breastfeeding: Generally considered safe, but dosage adjustments and monitoring by a doctor are necessary.
  • Avoid taking antacids, calcium or iron supplements, and multivitamins within at least 4 hours of taking THYROUP 100, as they can interfere with absorption.
  • Certain foods like soy products, walnuts, cottonseed meal, cabbage, cauliflower, dietary fiber, and calcium-fortified juices may affect the absorption of thyroxine; it is advisable to avoid these around dosing time.
  • Not recommended for treating obesity.

• Storage:

  • Store THYROUP 100 Tablet in a tightly sealed, light-resistant container.
  • Keep at normal room temperature, between 15-30°C.
  • Do not expose to excessive heat, cold, or damp conditions.
  • Keep out of the sight and reach of children.

THYROUP 100 by LUPIN LTD contains Levothyroxine sodium, a synthetic thyroid hormone used to treat an underactive thyroid gland.

What is THYROUP 100 used for?

THYROUP 100 is primarily used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormones. It is also used to manage goiter (an enlarged thyroid gland) and certain types of thyroid cancer. In some cases, it may be prescribed to test for hyperthyroidism or to treat myxedema coma, a severe complication of hypothyroidism.

How does THYROUP 100 work?

THYROUP 100 contains levothyroxine, which is a synthetic version of the natural thyroid hormone thyroxine (T4). Once ingested, T4 is converted into triiodothyronine (T3), the active form of the hormone, in the body's tissues, particularly in the liver and kidneys. These thyroid hormones regulate various metabolic processes, including caloric expenditure, protein synthesis, and are essential for normal growth and development, brain function, and maintaining body temperature.

What is the usual dosage for THYROUP 100?

The dosage of THYROUP 100 (Levothyroxine) is highly individualized and determined by your doctor based on factors like age, weight, thyroid hormone levels, and other health conditions. Adults typically start with 50-100 micrograms once a day, which may be gradually increased over several weeks to a usual daily dose of 100-200 micrograms. Patients over 50 or with heart conditions may start on a lower dose. Regular blood tests are necessary to monitor thyroid hormone levels and adjust the dose accordingly.

What are the possible side effects of THYROUP 100?

Most side effects of THYROUP 100 occur if the dose is too high, leading to symptoms similar to an overactive thyroid (hyperthyroidism). Common side effects can include headache, weight loss, diarrhea, changes in appetite, fever, changes in menstrual cycle, sensitivity to heat, excessive sweating, nervousness, irritability, sleeplessness, tremors, chest pain, and a fast or irregular heartbeat. Temporary hair loss may occur during the first few months of therapy, especially in children. If you experience severe symptoms like shortness of breath, hives, swelling of the face/lips/throat/tongue, or persistent severe side effects, contact your doctor immediately.

Is THYROUP 100 safe during pregnancy or breastfeeding?

Yes, THYROUP 100 (levothyroxine) is generally considered safe during pregnancy and breastfeeding. It is important to continue taking levothyroxine throughout pregnancy, as uncontrolled hypothyroidism can negatively impact both the mother and baby. Your doctor may need to adjust your dose during pregnancy and postpartum. While a small amount of levothyroxine passes into breast milk, it is typically too low to affect the baby and is important for maintaining adequate milk production in mothers with hypothyroidism.

Can THYROUP 100 be taken with other medications?

THYROUP 100 can interact with several medications, affecting its absorption or effectiveness. Some medicines that may interact include antacids, calcium salts, iron salts, orlistat, sucralfate, certain cholesterol-lowering medicines (e.g., colestyramine, colestipol), proton pump inhibitors, epilepsy medicines (e.g., carbamazepine, phenytoin), rifampicin, amiodarone, and estrogen-containing medicines (like combined contraceptive pills or HRT). It can also affect the dosage of diabetes medications and warfarin. Always inform your doctor or pharmacist about all prescription, over-the-counter, vitamin, and herbal supplements you are taking.

What precautions should be taken with THYROUP 100?

It is crucial to take THYROUP 100 exactly as prescribed. Do not use it for weight loss, as high doses can cause serious side effects. Inform your doctor if you have heart problems, high blood pressure, diabetes, adrenal gland problems, or osteoporosis, as these conditions may require dose adjustments or careful monitoring. Regular blood tests are essential to ensure the medication is working correctly and to prevent over- or under-treatment. Also, avoid taking calcium, iron, or antacids within 4 hours of taking levothyroxine. Grapefruit, coffee, milk, and soy products can also interfere with absorption, so separate their consumption by at least 30 minutes to 4 hours.

What happens if a dose of THYROUP 100 is missed?

If you miss a dose of THYROUP 100, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a forgotten one. Since levothyroxine stays in your body for several days, missing one or two doses usually won't cause immediate noticeable symptoms. However, consistent daily intake is important for maintaining stable thyroid hormone levels.

How should THYROUP 100 be stored?

Levothyroxine should be stored at room temperature (20-25°C or 68-77°F), protected from light and moisture. It is advisable to avoid storing medications in humid places like bathrooms, as heat and humidity can affect the tablet's potency. Keep it out of the sight and reach of children.