Gabastar Nt 100mg Tab

GABASTAR NT 100MG TAB is a combination medication manufactured by Lupin Ltd., primarily prescribed for the management of neuropathic pain. This condition arises from nerve damage, leading to symptoms such as burning, stabbing, or shooting pain, often accompanied by numbness or tingling.

Composition

Each tablet contains:

• Gabapentin: 100 mg
• Nortriptyline: 10 mg

Gabapentin is an alpha 2 delta ligand that reduces pain by modulating calcium channel activity in nerve cells. Nortriptyline, a tricyclic antidepressant, increases the levels of chemical messengers (serotonin and noradrenaline) in the brain, thereby stopping the movement of pain signals.

Uses

GABASTAR NT 100MG TAB is used to treat various forms of neuropathic pain, including:

• Diabetic Neuropathy (nerve damage due to diabetes)
• Post-Herpetic Neuralgia (nerve pain after shingles)
• Fibromyalgia (widespread musculoskeletal pain)
• Pain related to spinal cord injury
• Restless leg syndrome
• Sleep disturbances linked to nerve pain

Dosage and Administration

This medicine should be taken orally, with or without food, preferably at night. It's crucial to follow the doctor's prescribed dosage and not to stop the medication abruptly, as this can lead to withdrawal symptoms.

Side Effects

Common side effects include:

• Dizziness, drowsiness, and fatigue
• Dry mouth and constipation
• Blurred vision
• Weight gain
• Difficulty in urination
• Swelling of hands and feet (peripheral edema)

Serious side effects, though rare, can include mood changes (e.g., suicidal thoughts), severe allergic reactions, or irregular heartbeat, which require immediate medical attention.

Precautions

• Alcohol: Avoid alcohol consumption as it can increase drowsiness and dizziness.
• Driving/Operating Machinery: Due to potential drowsiness and dizziness, avoid driving or operating heavy machinery until you know how the medicine affects you.
• Pregnancy and Breastfeeding: Generally not recommended during pregnancy or breastfeeding due to potential risks to the fetus or infant.
• Medical Conditions: Inform your doctor if you have heart problems, kidney or liver impairment, or a history of bipolar disorder.
• Interactions: Inform your doctor about all other medications, supplements, or herbal products being taken to avoid potential drug interactions.

Storage

Store GABASTAR NT 100MG TAB at room temperature, ideally between 10°C to 30°C, away from moisture and heat, and out of reach of children and pets.

What is GABASTAR NT 100MG Tablet used for?

GABASTAR NT 100MG Tablet is primarily used for the treatment of neuropathic pain, which is pain caused by nerve damage. This can include conditions like diabetic neuropathy (nerve damage due to diabetes), post-herpetic neuralgia (nerve pain after shingles), fibromyalgia, and pain related to spinal cord injury.

How does GABASTAR NT 100MG Tablet work?

This medicine is a combination of two active ingredients: Gabapentin and Nortriptyline. Gabapentin works by modulating calcium channel activity in nerve cells, which decreases pain signals and dampens overactive nerves. Nortriptyline is a tricyclic antidepressant that increases the levels of chemical messengers, such as serotonin and noradrenaline, in the brain. These messengers help to stop the movement of pain signals in the brain. Together, these two components work to relieve neuropathic pain.

What is the usual dosage for GABASTAR NT 100MG Tablet?

The dosage and duration of GABASTAR NT 100MG Tablet should be precisely followed as prescribed by your doctor. It can be taken with or without food, but it is often recommended to take it at a fixed time each day, preferably at night, to maintain a consistent level of the medication in your body. Do not crush, chew, or break the tablet; swallow it whole with water.

What are the possible side effects of GABASTAR NT 100MG Tablet?

Common side effects include drowsiness, dizziness, dry mouth, constipation, blurred vision, weight gain, tiredness, and uncoordinated body movements. Less common but potentially serious side effects can include mood changes (such as depression or suicidal thoughts), difficulty breathing, irregular heartbeat, severe allergic reactions, muscle pain or weakness, and yellowing of the skin or eyes (jaundice). If you experience any severe or persistent side effects, contact your doctor immediately.

Is GABASTAR NT 100MG Tablet safe during pregnancy or breastfeeding?

GABASTAR NT 100MG Tablet is generally not recommended during pregnancy or breastfeeding. Animal studies have shown potential harmful effects on the developing baby. The medication can also pass into breast milk and may pose a risk to the infant. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding to discuss the potential risks and benefits.

Can GABASTAR NT 100MG Tablet be taken with other medications?

It is crucial to inform your doctor about all other medications, supplements, or herbal products you are currently taking, as GABASTAR NT can interact with various drugs.

• Antacids: Avoid taking antacids within 2 hours of GABASTAR NT, as they can reduce the absorption of the medicine.
• Alcohol: Avoid consuming alcohol, as it can significantly increase drowsiness and dizziness.
• Other CNS Depressants: Be cautious with other medications that cause drowsiness or affect the central nervous system.
• Specific Interactions: Certain medications, including monoamine oxidase inhibitors (MAOIs), medicines for opioid dependence, some cough/cold medicines, anesthetics, high blood pressure medicines, and certain antidepressants or epilepsy medicines, can interact with GABASTAR NT.

What precautions should be taken while using GABASTAR NT 100MG Tablet?

Do not stop taking GABASTAR NT 100MG Tablet suddenly, as this can lead to withdrawal symptoms or worsening of your condition; gradual dose tapering is usually required if the medication needs to be discontinued. Avoid driving or operating heavy machinery if you experience drowsiness or dizziness. Use with caution if you have kidney or liver disease, as dose adjustments may be necessary. It is contraindicated for patients with recent heart attacks, heartbeat disorders, heart blocks, or coronary artery disease. Regular monitoring for mood changes, depression, or suicidal thoughts is important. To manage potential weight gain, maintaining a healthy diet and regular exercise is advised. Rising slowly from a sitting or lying position can help prevent dizziness.

What happens if a dose of GABASTAR NT 100MG Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this can increase the risk of side effects.

How should GABASTAR NT 100MG Tablet be stored?

Store GABASTAR NT 100MG Tablet at room temperature, ideally between 10°C and 25°C or below 30°C. Keep it in a cool, dry place, away from direct sunlight and moisture. Always ensure the medicine is kept out of sight and reach of children and pets.