Wosulin R 40iu Vial 10ml

WOSULIN R 40IU VIAL 10ML

WOSULIN R 40IU VIAL 10ML is a fast-acting insulin product manufactured by Wockhardt Ltd., designed to manage blood sugar levels in individuals with diabetes mellitus.

• Name

  • Common Name: Regular Human Insulin / Soluble Human Insulin
  • Brand Name: WOSULIN R 40IU VIAL 10ML

• Composition Each ml contains:

  • Active Ingredient: Regular Human Insulin 40 IU
  • Preservative: m-Cresol 0.25% w/v

• Uses WOSULIN R 40IU VIAL 10ML is prescribed for the management of:

  • Type 1 Diabetes Mellitus
  • Type 2 Diabetes Mellitus It works by mimicking the body's natural insulin to facilitate glucose uptake by muscle and fat cells and reduces glucose production in the liver, thereby controlling blood sugar levels, especially after meals (postprandial hyperglycemia). This helps prevent long-term complications associated with diabetes, such as kidney damage, eye damage, and nerve problems.

• Dosage and Administration WOSULIN R 40IU VIAL 10ML is administered via subcutaneous injection (under the skin).

  • Sites: Common injection sites include the abdomen, thighs, upper arms, or buttocks.
  • Timing: It should typically be administered 20 to 30 minutes before a meal to ensure optimal absorption and effectiveness.
  • Guidance: The exact dosage and frequency are determined by a healthcare professional based on individual needs and blood sugar levels. Regular blood sugar monitoring is essential for dose adjustments.
  • Technique: Rotate injection sites to prevent lipodystrophy (thickening or thinning of fat tissue under the skin).

• Side Effects

  • Common Side Effects:
    • Hypoglycemia (low blood sugar), characterized by symptoms like cold sweats, anxiety, tremors, hunger, rapid heartbeat, headache, and nervousness.
    • Injection site reactions such as pain, redness, swelling, or itching.
    • Weight gain.
    • Lipodystrophy (abnormal changes in fat tissue at the injection site).
  • Less Common/Serious Side Effects:
    • Hypokalemia (low potassium levels).
    • Allergic reactions (skin rash, itching, swelling).
    • Edema (swelling due to fluid retention).

• Precautions

  • Hypoglycemia: WOSULIN R is contraindicated in individuals with existing hypoglycemia. Patients should be vigilant about symptoms of low blood sugar and carry sugary snacks.
  • Medical Conditions: Inform your doctor about any pre-existing kidney, liver, or heart conditions, as dosage adjustments may be necessary.
  • Pregnancy and Breastfeeding: Consult a doctor if pregnant or breastfeeding, as dosage adjustments might be required.
  • Alcohol Consumption: Alcohol intake can increase the risk of hypoglycemia and should be avoided or consumed with caution.
  • Driving/Operating Machinery: Be cautious, as fluctuations in blood sugar can affect the ability to concentrate and react.
  • Do not discontinue use without consulting a doctor.

• Storage

  • Unopened Vials: Must be stored in a refrigerator at a temperature between 2°C and 8°C (36°F and 46°F). Do not freeze.
  • Opened Vials: Can be stored at room temperature (below 25°C or up to 25°C) for up to 4 weeks (28 days).
  • Protect from direct light and moisture.
  • Keep out of the reach of children.

WOSULIN R 40IU VIAL 10ML is a human insulin product manufactured by Wockhardt Ltd, primarily used to manage blood sugar levels in individuals with diabetes mellitus.

Here are some frequently asked questions about WOSULIN R 40IU VIAL 10ML:

What is WOSULIN R used for?

WOSULIN R is a rapid-acting human insulin used to treat both Type 1 and Type 2 diabetes mellitus. It is also indicated for the initial stabilization of diabetes in patients with diabetic ketoacidosis, hyperosmolar non-ketotic syndrome, during periods of stress like severe infections or major surgery, and for the treatment of gestational diabetes.

How does WOSULIN R work?

WOSULIN R is a short-acting insulin that mimics the insulin naturally produced by the human pancreas. It works by facilitating the uptake of glucose into muscle and fat cells, which helps the body utilize sugar for energy. Simultaneously, it suppresses the production of glucose by the liver, thereby lowering blood sugar levels, especially after meals. Its onset of action is typically within 30 minutes, it reaches peak effect between 1-3 hours, and its duration of action is approximately 4-6 hours, extending up to 8 hours in some cases.

What is the usual dosage for WOSULIN R?

The dosage of WOSULIN R is highly individualized and determined by your physician based on your specific needs, blood sugar levels, and therapeutic response. For patients with Type 1 diabetes, the average total daily insulin requirement typically ranges from 0.5 to 1.0 IU/kg, while for Type 2 diabetes, it's approximately 0.3-0.6 IU/kg/day. It is usually administered subcutaneously (under the skin) 20 to 30 minutes before a meal. It's crucial to use a syringe marked for the correct strength (e.g., U-40 for WOSULIN R 40IU) to avoid dosage errors.

What are the possible side effects of WOSULIN R?

The most common side effect is hypoglycemia (low blood sugar), which can manifest as sweating, blurred vision, irregular heartbeat, hunger, tremors, anxiety, shakiness, and fatigue. Other potential side effects include reactions at the injection site such as pain, redness, swelling, itching, or rash. Less commonly, patients might experience weight gain, edema (tissue swelling), lipodystrophy (abnormal changes in fat tissue at injection sites), or hypokalemia (low potassium levels).

Is WOSULIN R safe during pregnancy or breastfeeding?

There are generally no restrictions on the use of insulin, including WOSULIN R, during pregnancy because insulin does not cross the placental barrier. It is also considered safe for use by nursing mothers, although the insulin dosage may need to be adjusted. Close monitoring of blood sugar levels is essential throughout pregnancy and breastfeeding.

Can WOSULIN R be taken with other medications?

WOSULIN R can interact with various medications. Your insulin requirements may be decreased by oral hypoglycemic agents, salicylates, sulfa antibiotics, monoamine oxidase inhibitors (MAOIs), angiotensin-converting enzyme (ACE) inhibitors, beta-blockers, octreotide, and alcohol. Conversely, medications like corticosteroids, isoniazid, certain lipid-lowering drugs (e.g., niacin), estrogens, oral contraceptives, phenothiazines, and thyroid replacement therapy may increase your insulin requirements. Beta-blockers may also mask the warning symptoms of hypoglycemia. Caution is advised when WOSULIN R is used with pioglitazone due to an increased risk of heart failure. Always inform your doctor about all medications you are taking.

What precautions should be taken while using WOSULIN R?

It is crucial to monitor your blood sugar levels regularly as advised by your doctor. Rotate injection sites within the same region (e.g., abdomen, thigh, upper arm) to prevent lipodystrophy. Always carry a fast-acting source of sugar, such as glucose tablets or candy, to treat potential hypoglycemia. Alcohol consumption should be avoided as it can significantly affect blood glucose levels. Exercise caution when driving or operating machinery, as hypoglycemia can impair your ability to concentrate and react. Inform your doctor if you have kidney, liver, or heart problems. Never stop taking WOSULIN R or adjust your dose without consulting your doctor.

What happens if a dose of WOSULIN R is missed?

If you miss a dose of WOSULIN R (a short-acting insulin) and it's less than 2 hours overdue, you may take the usual missed dose. If it's more than 2 hours overdue, it's generally advised to check your blood glucose and ketone levels. If ketones are low, you might withhold the missed dose and consider correcting high blood glucose at your next meal. For mixed insulin, if less than 2 hours overdue, take the usual dose; if more than 2 hours overdue, adjustments are made based on time and blood glucose/ketone levels, often involving a reduced dose or consideration of long-acting insulin. It is important never to double your next dose to compensate for a missed one. Always consult your doctor or healthcare provider for specific instructions regarding missed doses.

How should WOSULIN R be stored?

Unopened vials of WOSULIN R should be stored in a refrigerator at a temperature between 2°C and 8°C. It is crucial not to freeze the medicine. Once opened (when the stopper has been punctured), the vial can be kept at room temperature (15°C to 25°C or not above 30°C) for up to six weeks. Protect it from excessive heat and direct sunlight. Do not use WOSULIN R if it has been frozen or if the solution does not appear water-clear and colorless. Keep out of reach of children.