Arnicor 50 Mg Tablet (10 Tab)
Sacubitril (24mg) + Valsartan (26mg)
Source ID: 244379
₹206.25
₹155.10
(Inclusive of all taxes)Batch
BO240349A
PKG
10 TABLET
Expiry
2026-11-30
MRP
₹206.25
Stock
3
Discount
24.8%
Description
ARNICOR 50 MG TABLET
ARNICOR 50 MG TABLET by Cipla Ltd. is a combination medication used in the management of chronic heart failure. It belongs to a class of drugs known as Angiotensin Receptor Neprilysin Inhibitors (ARNIs), which work to improve heart function and reduce the risk of cardiovascular events.
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Name:
- Brand Name: ARNICOR 50 MG TABLET
- Common Name: Sacubitril/Valsartan 50 mg (24 mg Sacubitril and 26 mg Valsartan)
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Composition: Each film-coated tablet contains Sacubitril (24 mg) and Valsartan (26 mg) as a sodium salt complex.
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Uses: ARNICOR 50 MG TABLET is primarily indicated to reduce the risk of cardiovascular death and hospitalization for heart failure in adult patients with chronic heart failure (New York Heart Association Class II-IV) and reduced ejection fraction. It helps the heart pump blood more effectively, alleviating symptoms like breathlessness, fatigue, and swelling.
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Dosage and Administration: The medication should be taken as directed by a healthcare professional. It can be taken with or without food, ideally at the same time(s) each day for maximum benefit. Tablets should be swallowed whole and not crushed or chewed. The recommended starting dose of ARNICOR is often 49/51 mg (equivalent to 50mg of the complex) orally twice-daily, with the dose potentially doubled after 2 to 4 weeks to a target maintenance dose, as tolerated. Do not stop taking it without consulting your doctor.
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Side Effects: Common side effects may include dizziness, light-headedness (due to low blood pressure), cough, headache, tiredness, nausea, and signs of high potassium levels in the blood (hyperkalemia) which can cause irregular heartbeat or muscle weakness. Serious side effects like angioedema (swelling of the face, lips, tongue, or throat) are rare but require immediate medical attention.
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Precautions:
- ARNICOR 50 MG TABLET is contraindicated in pregnant and breastfeeding women.
- Caution is advised in patients with severe kidney or liver disease.
- Patients should inform their doctor about any history of angioedema or allergies to the ingredients.
- Avoid concomitant use with ACE inhibitors; a washout period of at least 36 hours is required when switching from an ACE inhibitor to ARNICOR.
- Concomitant use with potassium-sparing diuretics or potassium supplements may increase blood potassium levels.
- NSAIDs may reduce the blood pressure-lowering effect and increase the risk of kidney problems.
- Alcohol consumption should be limited as it may exacerbate dizziness.
- Dizziness or fatigue may occur, so caution is advised when driving or operating machinery.
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Storage: Store ARNICOR 50 MG TABLET at room temperature, ideally between 15°C and 30°C, away from direct light and moisture. Keep it out of reach of children.
₹206.25
₹155.10
(Inclusive of all taxes)Frequently Asked Questions
Here are frequently asked questions about ARNICOR 50 MG TABLET:
What is ARNICOR 50 MG TABLET used for?
ARNICOR 50 MG TABLET is primarily used to treat chronic heart failure with reduced ejection fraction (HFrEF) in adults. It helps reduce the risk of cardiovascular death and hospitalization, and can improve symptoms such as breathlessness, tiredness, and swelling. It may also aid in managing hypertension and providing cardiovascular protection.
How does ARNICOR 50 MG TABLET work?
ARNICOR 50 MG TABLET is a combination of two active ingredients: sacubitril and valsartan. Sacubitril inhibits an enzyme called neprilysin, which increases the levels of certain beneficial peptides that relax blood vessels and promote sodium excretion. Valsartan blocks angiotensin II type-1 (AT1) receptors, preventing the constriction of blood vessels. Together, these actions lead to the relaxation and widening of blood vessels, lowering blood pressure, reducing the heart's workload, and helping the body remove excess fluid, thereby improving the heart's pumping efficiency.
What is the usual dosage for ARNICOR 50 MG TABLET?
The recommended starting dose for ARNICOR (which contains 24 mg sacubitril and 26 mg valsartan for a total of 50 mg) is one tablet (49/51 mg) orally twice daily. Your doctor may increase this dose after 2 to 4 weeks to a target maintenance dose of 97/103 mg twice daily, depending on how you tolerate the medication. It can be taken with or without food, preferably at the same time each day. Always follow your doctor's specific instructions.
What are the possible side effects of ARNICOR 50 MG TABLET?
Common side effects include low blood pressure (hypotension), high potassium levels (hyperkalaemia), cough, dizziness, fatigue, nausea, diarrhea, weakness, headache, and decreased kidney function. More serious, though rare, side effects can include angioedema (severe swelling of the face, lips, tongue, or throat) which requires immediate medical attention.
Is ARNICOR 50 MG TABLET safe during pregnancy or breastfeeding?
No, ARNICOR 50 MG TABLET is contraindicated during pregnancy as it can cause serious harm or even endanger the life of the developing baby. It is also not recommended for use during breastfeeding, as it may pass into breast milk and potentially harm the infant. Women of childbearing potential should use reliable contraception while taking this medication.
Can ARNICOR 50 MG TABLET be taken with other medications?
ARNICOR 50 MG TABLET can interact with several medications. It is contraindicated with ACE inhibitors (e.g., enalapril, lisinopril) due to an increased risk of angioedema; a 36-hour washout period is required when switching from an ACE inhibitor to ARNICOR. Avoid taking it with other angiotensin receptor blockers (ARBs) or aliskiren (especially if you have diabetes or kidney disease). Caution is advised with potassium supplements or salt substitutes (due to risk of high potassium levels), NSAIDs (e.g., ibuprofen, naproxen) which can reduce its blood pressure-lowering effect and increase kidney problems, and lithium. Always inform your doctor about all medicines, vitamins, and herbal supplements you are currently taking.
What precautions should be taken while taking ARNICOR 50 MG TABLET?
Inform your doctor if you have a history of angioedema, kidney disease (dose adjustments and regular monitoring may be needed), or liver disease (not recommended in severe cases). Be cautious of sudden dizziness when standing up by rising slowly, as low blood pressure can occur. Avoid potassium-rich foods and supplements unless directed by your doctor. It's also advisable to limit or avoid alcohol consumption as it may further lower blood pressure and increase dizziness. Regular monitoring of blood pressure, kidney function, and potassium levels is recommended during treatment.
What happens if a dose of ARNICOR 50 MG TABLET is missed?
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
How should ARNICOR 50 MG TABLET be stored?
Store ARNICOR 50 MG TABLET at room temperature, ideally between 15°C and 30°C (or below 30°C), in a cool, dry place. Keep it away from direct sunlight, moisture, and out of the reach and sight of children. Always keep the medicine in its original packaging and check the expiry date before use.