Metosartan Ch 25/6.25 Mg (10 Tab)

METOSARTAN CH 25/6.25 MG (10 TAB) by SUN PHARMA LABORATORIES LTD.

Name:

• Brand Name: METOSARTAN CH 25/6.25 (also referred to as METOSARTAN CH 25/6.25/40mg or METOSARTAN CH 25)
• Common Name: Chlorthalidone, Metoprolol, and Telmisartan combination tablet.

Composition: Each tablet typically contains the following active ingredients:

• Chlorthalidone: 6.25 mg
• Metoprolol: 25 mg (often Metoprolol Succinate, though some sources just list Metoprolol)
• Telmisartan: 40 mg

Uses: METOSARTAN CH 25/6.25 MG is an antihypertensive medication primarily used for the treatment of high blood pressure (hypertension). By effectively lowering blood pressure, it helps reduce the risk of serious cardiovascular complications such as heart attack, stroke, and kidney damage. This medicine works by relaxing blood vessels, slowing the heart rate, and promoting the removal of excess fluid and electrolytes from the body.

Dosage and Administration: This medication is typically taken orally once daily, or once in two days, as directed by a healthcare provider. It can be taken with or without food. To maintain consistency and optimize benefits, it is recommended to take it at the same time each day, preferably in the morning to avoid frequent nighttime urination due to its diuretic effect. Do not chew, crush, or break the tablet; swallow it whole with water. Do not exceed the prescribed dose or discontinue the medicine without consulting a doctor.

Side Effects: Common side effects may include:

• Headache
• Dizziness
• Nausea and stomach upset
• Diarrhea
• Fatigue or weakness
• Slow heart rate
• Cold extremities or numbness
• Low blood pressure
• Increased blood lipid levels and uric acid levels

Serious side effects are less common but can include blurred vision, hypoglycemia, and chest pain. Consult your doctor if any side effects persist or worsen.

Precautions:

• Allergies: Do not take this medicine if you are allergic to Chlorthalidone, Metoprolol, Telmisartan, or any other beta-blockers.
• Pregnancy and Breastfeeding: METOSARTAN CH is not recommended during pregnancy due to potential risks to the fetus and should be discontinued as soon as pregnancy is detected. It is generally advised to use with caution or avoid during breastfeeding, as it may transfer into breast milk. Consult a doctor before use if pregnant or breastfeeding.
• Medical Conditions: Inform your doctor if you have diabetes, circulation problems, asthma, thyroid disorders (including hyperthyroidism), adrenal gland tumors (phaeochromocytoma), heart, kidney, or liver problems, or if you are on a low-salt diet.
• Alcohol: Avoid or limit alcohol consumption as it may increase dizziness and further lower blood pressure.
• Driving: May cause dizziness or tiredness, so drive with caution.
• Diet: Avoid potassium-rich foods (e.g., bananas, spinach) and high-sodium foods.
• Interactions: Inform your doctor about all other medications, especially NSAIDs, antidiabetic medicines, and other antihypertensives, to avoid potential drug interactions.

Storage: Store in a cool and dry place, away from direct sunlight. Protect from light and moisture. Keep out of reach and sight of children. Store at room temperature (20-25°C or below 30°C).

What is METOSARTAN CH 25/6.25 MG used for?

METOSARTAN CH 25/6.25 MG is primarily used to treat hypertension (high blood pressure). It helps lower blood pressure, thereby reducing the chances of developing serious heart problems such as heart attack and stroke. It can also manage essential hypertension in patients with stable coronary artery disease.

How does METOSARTAN CH 25/6.25 MG work?

This medicine is a combination of three active ingredients: Chlorthalidone, Metoprolol Succinate, and Telmisartan.

• Chlorthalidone is a diuretic that helps remove excess fluid and electrolytes from the body through urine, which lowers blood pressure and reduces swelling. It works by inhibiting the reabsorption of sodium and chloride in the kidneys.
• Telmisartan is an angiotensin receptor blocker (ARB). It relaxes blood vessels by blocking the action of angiotensin II, a substance in the body that causes blood vessels to narrow, thus lowering blood pressure.
• Metoprolol Succinate is a beta-blocker that slows down the heart rate and reduces the force of heart contractions. This makes it easier for the heart to pump blood throughout the body and further contributes to lowering blood pressure. It selectively blocks beta-1 adrenergic receptors in the heart.

What is the usual dosage of METOSARTAN CH 25/6.25 MG?

The specific dosage of METOSARTAN CH 25/6.25 MG typically refers to a combination of Metoprolol Succinate 25 mg, Chlorthalidone 6.25 mg, and Telmisartan 40 mg. It is usually taken orally, once daily. It's best to take it at the same time each day, with or without food. To avoid frequent urination disrupting sleep, it is often advised to take it during the day or at least 4 hours before bedtime. Always follow your doctor's prescribed dose and duration.

What are the possible side effects of METOSARTAN CH 25/6.25 MG?

Common side effects can include headache, nausea, dizziness, stomach upset, diarrhea, constipation, weakness, fatigue, slow heart rate, and low blood pressure. Some individuals may experience cold extremities or numbness. This medication can also cause electrolyte imbalances such as low potassium, sodium, and magnesium levels, or increased uric acid and blood lipid levels. If you experience persistent or worsening side effects, consult your doctor.

Is METOSARTAN CH 25/6.25 MG safe during pregnancy or breastfeeding?

• Pregnancy: METOSARTAN CH 25/6.25 MG is generally considered unsafe during pregnancy, with definite evidence of risk to the developing baby. It should be discontinued as soon as possible, especially during the second and third trimesters, as it might affect the fetus. Your doctor may only prescribe it in rare, life-threatening situations where the benefits significantly outweigh the risks.
• Breastfeeding: While limited human data suggests it is probably safe with no significant risk to the baby, it is generally advised to avoid this medication during breastfeeding as components may pass into breast milk. Always consult your doctor for advice on suitable alternatives.

Can METOSARTAN CH 25/6.25 MG be taken with other medications?

METOSARTAN CH 25/6.25 MG can interact with various medications. It's crucial to inform your doctor about all medicines you are currently taking, including over-the-counter drugs and herbal supplements, to prevent potential interactions.

• Combining it with other blood pressure-lowering medications (e.g., ACE inhibitors, other ARBs, calcium channel blockers) can increase the risk of low blood pressure, kidney impairment, or high blood potassium.
• Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or aspirin may reduce its effectiveness and increase the risk of kidney damage.
• Antidepressants (e.g., lithium, fluoxetine) and certain antiarrhythmics (e.g., amiodarone) can also interact.
• If you have diabetes, dose adjustments of your diabetes medication (e.g., insulin) may be needed as this medicine can affect blood glucose levels.

What precautions should be taken while using METOSARTAN CH 25/6.25 MG?

• Alcohol: Avoid or limit alcohol consumption as it can increase dizziness and further lower blood pressure.
• Driving/Machinery: This medicine may cause dizziness or fatigue, so avoid driving or operating heavy machinery until you know how it affects you.
• Position Changes: Rise slowly from a sitting or lying position to prevent dizziness due to a sudden drop in blood pressure (orthostatic hypotension).
• Medical Conditions: Inform your doctor if you have diabetes, circulation problems, asthma, thyroid disorder, adrenal gland tumor, or existing heart, kidney, or liver problems.
• Diet: Avoid a high-potassium diet, including potassium-rich foods like bananas, broccoli, and potassium supplements.
• Monitoring: Regular monitoring of blood pressure, kidney function, electrolytes, and blood glucose levels is recommended.
• Children: It is not recommended for use in children.

What happens if a dose of METOSARTAN CH 25/6.25 MG is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should METOSARTAN CH 25/6.25 MG be stored?

Store METOSARTAN CH 25/6.25 MG in a cool and dry place, away from direct sunlight. It should be kept at room temperature (20-25°C) and protected from moisture and light. Always keep this medicine out of the reach and sight of children.