Azulix Dm 1/10/1000 Tab

AZULIX DM 1/10/1000 Tablet

Name:

• Brand Name: AZULIX DM 1/10/1000 TAB
• Common Name: Dapagliflozin, Glimepiride, Metformin Hydrochloride Tablets

Composition: Each film-coated bilayer tablet contains a fixed dose of:

• Dapagliflozin 10 mg
• Glimepiride 1 mg
• Metformin Hydrochloride 1000 mg

Uses: AZULIX DM 1/10/1000 Tablet is prescribed for the management of Type 2 Diabetes Mellitus in adults, as an adjunct to diet and exercise, to improve glycemic control. It helps control high blood sugar levels, reduces the chances of serious diabetes complications like kidney damage and blindness, and may help prevent heart disease. This medicine works by removing excess glucose through urine (Dapagliflozin), stimulating insulin release from the pancreas (Glimepiride), and reducing glucose production in the liver while improving insulin sensitivity (Metformin).

Dosage and Administration: The typical recommended dose is one tablet daily, as directed by a physician. It can be taken with or without food, preferably at the same time each day to help remember. Tablets should be swallowed whole. Do not alter the prescribed dosage or stop taking the medicine without consulting your doctor.

Side Effects: Common side effects include low blood sugar (hypoglycemia), dizziness, headache, nausea, diarrhea, stomach upset, and genital yeast infections or urinary tract infections. Serious side effects, though rare, can include lactic acidosis, severe urinary tract infections, and severe allergic reactions.

Precautions:

• Kidney and Liver Impairment: Use with caution in patients with kidney or liver problems. It is contraindicated in severe kidney disease or those on dialysis.
• Alcohol: Avoid excessive alcohol consumption as it may increase the risk of lactic acidosis and low blood sugar.
• Pregnancy and Breastfeeding: Consult your doctor before use during pregnancy or breastfeeding.
• Hypoglycemia: Patients should be aware of the risk of hypoglycemia, especially when combined with other antidiabetic agents, and carry a quick source of sugar.
• Dehydration: Stay hydrated as the medicine may increase urination.
• Allergy: Contraindicated if allergic to dapagliflozin, glimepiride, metformin, or sulfonamide derivatives.

Storage: Store at room temperature not exceeding 30°C. Keep tablets in their original packaging, in a dry place, away from direct sunlight, and out of reach of children. Do not use after the expiry date.

AZULIX DM 1/10/1000 is a combination medication used to manage Type 2 diabetes mellitus in adults. It contains Dapagliflozin (10mg), Glimepiride (1mg), and Metformin Hydrochloride (1000mg extended-release).

What is AZULIX DM 1/10/1000 used for?

AZULIX DM 1/10/1000 is used to treat Type 2 diabetes mellitus in adults. It helps to control high blood sugar levels when diet and exercise alone are not sufficient. This medication aims to improve glycemic control, prevent serious complications of diabetes like kidney damage, nerve issues, and vision problems, and may also help prevent heart disease.

How does AZULIX DM 1/10/1000 work?

This medicine works through three active ingredients:

• Dapagliflozin: A sodium-glucose co-transporter 2 (SGLT2) inhibitor, it works by blocking glucose reabsorption in the kidneys, leading to the removal of excess sugar through urine.
• Glimepiride: A sulfonylurea that stimulates the beta cells in the pancreas to produce more insulin, helping the body regulate blood glucose more effectively.
• Metformin: A biguanide that primarily reduces glucose production in the liver and delays glucose absorption from the intestines. It also improves insulin sensitivity in body tissues.

What is the usual dosage for AZULIX DM 1/10/1000?

The usual dosage of AZULIX DM 1/10/1000 is one tablet daily, as prescribed by your doctor. It can be taken with or without food, but taking it with meals may help reduce stomach upset. Tablets should be swallowed whole. Do not alter your dose or stop taking the medicine without consulting your doctor, as this can lead to increased blood sugar levels and potential complications.

What are the possible side effects of AZULIX DM 1/10/1000?

Common side effects include:

• Hypoglycemia (low blood sugar), with symptoms like sweating, dizziness, confusion, or trembling.
• Genital mycotic infections (fungal infections, e.g., vaginal yeast infections or balanitis).
• Urinary tract infections (UTIs) and increased urination.
• Nausea, vomiting, diarrhea, and stomach discomfort.
• Headache and dizziness. Serious but rare side effects can include lactic acidosis and diabetic ketoacidosis. If side effects persist or worsen, consult your doctor.

Is AZULIX DM 1/10/1000 safe during pregnancy or breastfeeding?

Caution is advised during pregnancy. AZULIX DM 1/10/1000 may be unsafe to use during pregnancy, and insulin is often required under such circumstances. It is generally not recommended during breastfeeding, as information on whether it passes into human breast milk is not available. Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding.

Can AZULIX DM 1/10/1000 be taken with other medications?

AZULIX DM 1/10/1000 can interact with certain medications. Inform your doctor about all medicines, supplements, or herbal products you are taking to avoid possible interactions. Key interactions include:

• Diuretics (e.g., furosemide, hydrochlorothiazide): May increase the risk of volume depletion and low blood pressure.
• Insulin and insulin secretagogues (e.g., Gliclazide, Glipizide): Can enhance blood glucose-lowering effects, potentially causing hypoglycemia.
• Non-steroidal anti-inflammatory medicines (NSAIDs like Ibuprofen, Diclofenac): May worsen kidney function.
• Alcohol: Avoid alcohol consumption as it can increase the risk of low blood sugar and lactic acidosis.
• Corticosteroids: May reduce the blood glucose-lowering effect.

What precautions should be taken?

• Kidney and Liver Problems: Use with caution if you have kidney or liver problems. The medicine is contraindicated in severe kidney disease or if you are on dialysis. Regular monitoring of kidney function is recommended.
• Dehydration: Stay hydrated throughout the day, as this medicine may increase urination and raise the risk of dehydration.
• Allergies: Do not take if you are allergic to dapagliflozin, glimepiride, metformin, or any other ingredients.
• Alcohol: Avoid alcohol due to increased risk of low blood sugar and lactic acidosis.
• Driving/Operating Machinery: Exercise caution as the medicine may cause low blood sugar levels, which could affect concentration.
• Diet and Exercise: This medicine is part of a treatment program that should include a healthy diet, regular exercise, and weight reduction.

What happens if a dose is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should AZULIX DM 1/10/1000 be stored?

Store AZULIX DM 1/10/1000 at room temperature, not exceeding 30°C, in a cool, dry place. Keep the tablets in their original packaging to protect them from light and moisture. Store in a dry place away from direct sunlight and out of reach of children. Do not use the tablets after the expiry date printed on the package.