Febucip 80

Here is a detailed product description for FEBUCIP 80 by CIPLA LTD:

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FEBUCIP 80

• Name:

  • Common Name: Febucip 80
  • Brand Name: FEBUCIP 80 (manufactured by Cipla Ltd.)

• Composition:

  • Each tablet contains Febuxostat 80 mg.
  • Febucip 80 is classified as a xanthine oxidase inhibitor.

• Uses: FEBUCIP 80 is primarily used for the chronic management of high uric acid levels (hyperuricemia) in adults with gout. It is suitable for patients who have not responded well to allopurinol, are intolerant to it, or when allopurinol is medically inadvisable.

  • Gout Management: Lowers uric acid levels to prevent the formation of uric acid crystals in joints, thereby reducing pain, swelling, and inflammation associated with gout attacks.
  • Prevention of Gout Attacks: Helps prevent future gout flare-ups.
  • Chronic Kidney Disease Support: May support patients by managing uric acid levels.
  • Uric Acid Nephrolithiasis Prevention: Can prevent uric acid kidney stones.
  • Treatment of Tumor Lysis Syndrome: Manages high uric acid levels in chemotherapy patients.

• Dosage and Administration:

  • The typical recommended dose is 80 mg once daily, or as directed by a healthcare professional.
  • Tablets should be swallowed whole with a glass of water, without breaking or chewing.
  • Can be taken with or without food.
  • For maximum effectiveness, take the medicine at the same time each day.
  • Do not exceed the prescribed dose or discontinue treatment without consulting your doctor, even if symptoms improve, as stopping may worsen the condition.

• Side Effects:

  • Common Side Effects: Nausea, joint pain, rash, diarrhoea, headache, swelling (oedema), dizziness, abnormal liver function test results, muscle pain. An increase in gout flare-ups may occur during the initial months of treatment.
  • Serious Side Effects: Include liver dysfunction, severe skin and allergic reactions (e.g., severe rash, itching, swelling of face/tongue/throat, difficulty breathing), and cardiovascular events such as heart attack or stroke. Seek immediate medical attention if serious side effects occur.

• Precautions:

  • Allergy: Do not use if allergic to Febucip 80 or its components.
  • Medical Conditions: Use with caution in patients with heart problems, liver problems (including severe), or kidney problems (especially severe). Regular monitoring of liver and kidney function may be advised.
  • Pregnancy and Breastfeeding: Caution is advised. Consult a doctor as it may be unsafe during pregnancy and breastfeeding.
  • Alcohol: Caution advised as alcohol consumption can worsen gout or affect the medicine's effectiveness.
  • Driving/Operating Machinery: May cause dizziness or drowsiness; avoid these activities if affected.
  • Children: Not recommended for use in individuals under 18 years of age.
  • Drug Interactions: May interact with immunosuppressants (e.g., azathioprine, mercaptopurine), some anti-diabetes medications (e.g., rosiglitazone), antihypertensives (e.g., losartan, amlodipine), statins (e.g., atorvastatin), and theophylline, potentially increasing toxicity. Inform your doctor about all current medications.

• Storage:

  • Store at room temperature, ideally between 20°C to 25°C or below 30°C.
  • Keep in a cool, dry place away from direct sunlight and moisture.
  • Keep out of sight and reach of children.
  • Always check the expiry date on the packaging.

FEBUCIP 80 (Febuxostat 80mg) is a medication primarily used for the management of high uric acid levels (hyperuricemia) in adults with gout. It is manufactured by Cipla Ltd..

What is FEBUCIP 80 used for?

FEBUCIP 80 is used to treat and prevent gout, a type of arthritis characterized by sudden and severe pain, swelling, redness, and warmth in the joints due to the accumulation of uric acid crystals. It is typically prescribed for adults who have not responded well to other medications like allopurinol or are intolerant to them. It also helps manage chronic hyperuricemia and can prevent uric acid kidney stones. In some cases, it's used to prevent high uric acid levels in patients undergoing chemotherapy for blood cancers.

How does FEBUCIP 80 work?

FEBUCIP 80 contains febuxostat, which belongs to a class of medications called xanthine oxidase inhibitors. It works by inhibiting the enzyme xanthine oxidase, which is responsible for converting purines into uric acid in the body. By reducing the production of uric acid, FEBUCIP 80 lowers uric acid levels in the blood, preventing the formation and accumulation of urate crystals in joints and kidneys, thereby reducing gout attacks and inflammation.

What is the usual dosage for FEBUCIP 80?

The usual recommended dose for adults is one 80 mg tablet once daily, with or without food. Your doctor may adjust the dosage based on your response to treatment, kidney function, and other medical conditions. It is important to take the tablet at the same time each day to maintain consistent levels in your body.

What are the possible side effects of FEBUCIP 80?

Common side effects include headache, skin rashes, diarrhea, nausea, joint pain, dizziness, and abnormal liver function. During the initial months of treatment, you might experience an increase in gout flare-ups. Serious side effects can include heart problems, liver problems, and severe allergic reactions. If you experience symptoms like chest pain, shortness of breath, severe dizziness, skin rash, itching, swelling of the face or throat, or breathing difficulty, seek immediate medical attention.

Is FEBUCIP 80 safe during pregnancy or breastfeeding?

FEBUCIP 80 is generally not recommended during pregnancy and should only be used if prescribed by a doctor, who will weigh the potential benefits against the risks. Similarly, it is probably unsafe to use while breastfeeding, and caution is advised. Consult your doctor if you are pregnant or breastfeeding before taking this medicine.

Can FEBUCIP 80 be taken with other medications?

FEBUCIP 80 can interact with certain medications. It is crucial to inform your doctor about all current medications you are taking to avoid undesired effects. Specifically, it may intensify the effects of immunosuppressants like azathioprine and mercaptopurine, and also increase the toxicity of medications like rosiglitazone and certain antihypertensives (e.g., losartan, amlodipine) and statins (e.g., atorvastatin). It may also interact with theophylline.

What precautions should be taken while using FEBUCIP 80?

Before taking FEBUCIP 80, inform your doctor if you have heart, liver, kidney, or thyroid problems. Patients with a history of cardiovascular disease should use it with caution as it may worsen their condition. Regular blood tests to monitor liver function may be advised. Avoid driving or operating heavy machinery if you experience dizziness or drowsiness. Do not discontinue the medication without consulting your doctor, even if you feel better, as stopping can increase uric acid levels and worsen symptoms.

What happens if a dose of FEBUCIP 80 is missed?

If you miss a dose of FEBUCIP 80, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should FEBUCIP 80 be stored?

FEBUCIP 80 should be stored in a cool and dry place, away from direct sunlight and moisture. Keep it out of sight and reach of children. Store at room temperature, ideally between 20°C to 25°C.