Brivgard 25mg Tab

BRIVGARD 25MG TABLET

BRIVGARD 25MG Tablet is an anti-epileptic medication manufactured by Lupin Ltd-Mindnext Div.

• Name:

  • Brand Name: Brivgard 25mg Tablet
  • Common Name: Brivaracetam (active ingredient)

• Composition:

  • Each tablet contains 25mg of Brivaracetam.

• Uses: Brivgard 25mg Tablet is primarily used for the management and treatment of seizures (fits) in individuals with epilepsy. It is specifically indicated for:

  • Partial-onset seizures (also known as focal seizures) in patients with epilepsy.
  • It can be used as monotherapy (on its own) or as adjunctive therapy (in combination with other anti-epileptic medications).

• Dosage and Administration:

  • Take Brivgard 25mg Tablet precisely as prescribed by your doctor.
  • It is typically taken once or twice daily, with or without food.
  • Swallow the tablet whole with water; do not crush, chew, or break it.
  • Maintain consistent timing for taking the medicine each day to maximize its effectiveness.
  • Do not stop taking this medicine abruptly, as sudden withdrawal can lead to increased frequency of seizures or status epilepticus. The dosage may be adjusted gradually by your doctor.

• Side Effects: Common side effects often subside as your body adjusts to the medication.

  • Common: Sleepiness, dizziness, fatigue, headache, nausea, vomiting, irritability, agitation, and coordination problems.
  • Serious/Less Common: Behavioral changes, aggression, neuropsychiatric symptoms, anxiety, depression, thoughts of self-harm or suicide, and rarely, allergic reactions. Consult your doctor if these worsen or become concerning.

• Precautions:

  • Pregnancy: Not recommended during pregnancy unless considered necessary by a doctor, due to limited safety information and potential risks to the unborn baby.
  • Breastfeeding: Not recommended for use in breastfeeding women as it may pass into breast milk.
  • Liver/Kidney Problems: Inform your doctor if you have liver or kidney problems, as dose adjustment may be required.
  • Driving and Operating Machinery: This medicine can cause drowsiness, dizziness, tiredness, and lack of coordination. Avoid driving or operating heavy machinery until you know how it affects you.
  • Alcohol: Avoid alcohol consumption while taking Brivgard 25mg Tablet, as it may enhance drowsiness and other side effects.
  • Drug Interactions: Inform your doctor about all other medicines, supplements, or herbal products you are taking to avoid potential interactions, especially with rifampicin and St. John's wort.
  • Behavioral Changes: Report any unusual changes in mood or behavior, including depression, anxiety, aggression, or suicidal thoughts, to your doctor.

• Storage:

  • Store in a cool and dry place, below 25°C or below 30°C, away from direct sunlight.
  • Keep it in the original packaging to protect it from moisture.
  • Keep out of the reach and sight of children and pets.

Here are some frequently asked questions about BRIVGARD 25MG TAB (Brivaracetam), along with concise answers:

1. What is BRIVGARD 25MG TAB used for?

BRIVGARD 25MG TAB, which contains the active ingredient Brivaracetam, is used to help control partial-onset seizures in individuals with epilepsy. It can be used alone or in combination with other medications for seizure management in adults and children aged 1 month and older.

2. How does BRIVGARD 25MG TAB work?

Brivaracetam works by binding to a specific protein in the brain called synaptic vesicle glycoprotein 2A (SV2A). This action helps to stabilize abnormal electrical activity in the brain, thereby preventing or reducing the frequency and severity of seizures.

3. What is the usual dosage for BRIVGARD 25MG TAB?

For adults and adolescents 16 years of age and older, the typical starting dose is 50 milligrams (mg) twice a day, which can be adjusted by your doctor between 25 mg and 100 mg twice daily, depending on individual response and tolerability. For children aged 1 month to less than 16 years, the dosage is determined by body weight. Tablets should be swallowed whole with liquid and can be taken with or without food.

4. What are the possible side effects of BRIVGARD 25MG TAB?

Common side effects include drowsiness, dizziness, fatigue, nausea, vomiting, and constipation. More serious side effects, though less common, can include changes in mood or behavior (such as depression, anxiety, agitation, aggression, or suicidal thoughts), problems with coordination or balance, and severe allergic reactions (e.g., swelling of the face, lips, tongue, or throat, or difficulty breathing). It is important to tell your doctor about any unusual or concerning symptoms.

5. Is BRIVGARD 25MG TAB safe during pregnancy or breastfeeding?

For pregnancy, Brivaracetam is classified under Pregnancy Category C, meaning caution is advised, but the potential benefits may outweigh the risks. It is not known if it will harm an unborn baby. Brivaracetam is present in breast milk, and limited information suggests infants might have serum levels in the therapeutic range with exclusive breastfeeding. If you are pregnant, planning to become pregnant, or breastfeeding, you should discuss the risks and benefits with your healthcare provider.

6. Can BRIVGARD 25MG TAB be taken with other medications?

Brivaracetam generally has few clinically relevant drug-drug interactions with most other anti-epileptic drugs. However, coadministration with carbamazepine may increase levels of carbamazepine-epoxide (an active metabolite of carbamazepine), and phenytoin levels might increase when taken with Brivaracetam. Additionally, medications like rifampin can decrease Brivaracetam's plasma concentrations. Alcohol and other sedating medications can also increase the sedative effects of Brivaracetam. Always inform your doctor about all prescription, over-the-counter medications, vitamins, and herbal supplements you are taking.

7. What precautions should be taken while on BRIVGARD 25MG TAB?

Do not stop taking BRIVGARD suddenly, as this can lead to an increase in seizure frequency or severity. Your doctor will advise on how to gradually reduce the dose if needed. Monitor for any changes in mood or behavior, including suicidal thoughts, and report them to your doctor immediately. Exercise caution when driving or operating machinery until you understand how the medicine affects you, as it can cause dizziness or drowsiness. Patients with liver problems or a history of alcohol or drug abuse should also use this medication with caution and inform their doctor.

8. What happens if a dose of BRIVGARD 25MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are unsure, contact your healthcare provider for advice.

9. How should BRIVGARD 25MG TAB be stored?

Store BRIVGARD 25MG TAB tablets at room temperature, typically between 20°C to 25°C (68°F to 77°F), away from heat, moisture, and direct light. The oral solution form should not be frozen and any opened bottle should be discarded after 5 months, even if some medicine remains. Keep all medications out of the reach of children.