Ibugesic Plus Tab

IBUGESIC PLUS TAB by CIPLA-OPTIMUS DIV

• Name: Ibugesic Plus Tablets. Other known names include Combiflam, Advil Dual Action, Ibubid Plus, Lederflam Plus, and Zupar Tab.

• Composition: Each uncoated Ibugesic Plus tablet contains Ibuprofen 400 mg (IP) and Paracetamol (Acetaminophen) 325 mg (IP).

• Uses: Ibugesic Plus Tablets are indicated for the short-term management of mild to moderate pain, inflammation, and fever. It is commonly used for:

  • Headaches, including migraines.
  • Toothaches and dental pain.
  • Muscular aches and body pain.
  • Backaches.
  • Pain due to inflammation, such as in arthritis, sprains, and strains.
  • Menstrual cramps (dysmenorrhea).
  • Post-surgical pain.
  • Reduction of fever.

• Dosage and Administration:

  • Adults and Children (12 Years of Age and Over): One tablet thrice daily, or one tablet every 6-8 hours as needed. Do not exceed 3-4 tablets (1200 mg ibuprofen / 975 mg paracetamol) in 24 hours.
  • Take Ibugesic Plus with food or milk to reduce the risk of stomach discomfort and irritation.
  • The lowest effective dose should be used for the shortest duration necessary to relieve symptoms.
  • Do not crush or chew the tablet.
  • If symptoms persist for more than 3 days for fever or 7 days for pain, consult a physician.

• Side Effects:

  • Common: Heartburn, indigestion, nausea, stomach pain, upset stomach, dizziness, headache, sleepiness.
  • Serious: Gastrointestinal bleeding, ulceration, or perforation (especially with long-term use), liver damage (associated with paracetamol overdose), kidney strain, skin reactions (rashes, itching, severe allergic reactions), and increased risk of cardiovascular thrombotic events (myocardial infarction, stroke).

• Precautions:

  • Contraindicated in patients with known hypersensitivity to paracetamol, ibuprofen, other NSAIDs, or any excipients.
  • Avoid concomitant use with other products containing paracetamol, ibuprofen, aspirin, or other anti-inflammatory medicines unless directed by a doctor.
  • Use with caution in patients with heart disease, high blood pressure, heart failure, or conditions predisposing to fluid retention.
  • Caution is advised for patients with a history of peptic ulcer, gastrointestinal irritation, diverticulosis, ulcerative colitis, Crohn's disease, or other inflammatory bowel diseases.
  • Patients with impaired renal or hepatic function should use with care; large doses should be avoided in hepatic impairment.
  • Avoid alcohol consumption during treatment due to increased risk of side effects, including gastrointestinal bleeding and liver damage.
  • Pregnant or breastfeeding women should consult their doctor before use.
  • NSAIDs may increase the risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. This risk may increase with duration of use.
  • IBUGESIC PLUS is contraindicated for the treatment of peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery.

• Storage: Store in a cool, dry place away from sunlight, typically below 30°C or at controlled room temperature (20 to 25°C). Keep out of sight and reach of children.

Ibugesic Plus Tablet by Cipla-Optimus Div is a combination medication containing Ibuprofen and Paracetamol, commonly used for pain relief and fever reduction. It addresses various types of mild to moderate pain and also helps reduce inflammation.

Here are some frequently asked questions about Ibugesic Plus Tablet:

What is Ibugesic Plus Tablet used for?

Ibugesic Plus Tablet is primarily used to relieve mild to moderate pain and reduce fever. It is effective for conditions such as headaches, toothaches, muscular aches, backaches, menstrual pain, joint pain, arthritis, and dental pain. It also helps in reducing inflammation.

How does Ibugesic Plus Tablet work?

This medication combines two active ingredients: Ibuprofen and Paracetamol (Acetaminophen). Ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), works by blocking the production of prostaglandins, chemicals in the body responsible for pain and inflammation. Paracetamol acts as an analgesic (pain reliever) and antipyretic (fever reducer) by reducing pain signals to the brain and inhibiting prostaglandin synthesis to lower elevated body temperature.

What is the usual dosage for Ibugesic Plus Tablet?

For adults, the general recommendation is one tablet every 6-8 hours. However, you should not take more than four tablets in a 24-hour period. It is intended for short-term use only, typically not exceeding 3 days for fever or 4 days for pain without consulting a doctor. The tablet should be taken with food or milk to minimize stomach discomfort. Ibugesic Plus Tablets are contraindicated for children below 12 years of age or those weighing less than 40 kg.

What are the possible side effects of Ibugesic Plus Tablet?

Common side effects may include heartburn, indigestion, nausea, stomach pain, upset stomach, headache, and dizziness. More serious but less common side effects can involve stomach ulcers or bleeding (especially with long-term use), liver damage (particularly with overdose), kidney strain, and severe allergic reactions like skin rashes or breathing difficulties. If any side effects persist or worsen, consult your doctor.

Is Ibugesic Plus Tablet safe during pregnancy or breastfeeding?

Ibugesic Plus Tablet is generally not recommended during pregnancy, especially in the last trimester, due to potential risks to the fetus, including heart and kidney problems, delayed labor, and increased bleeding risk for both mother and baby. Women who are trying to conceive should also avoid this medication. For breastfeeding mothers, it should be used with caution, for short durations, and at the lowest possible dose, only after consulting a doctor, as components may pass into breast milk in low concentrations.

Can I take Ibugesic Plus Tablet with other medications?

It is crucial to avoid taking Ibugesic Plus Tablet with other medicines containing paracetamol, ibuprofen, aspirin, or other NSAIDs unless specifically directed by a doctor, due to the risk of additive side effects and overdose. Caution is advised when taken with blood thinners (anticoagulants), diuretics, certain antihypertensive medications (like ACE inhibitors), methotrexate, lithium, oral hypoglycemic agents, and glucocorticoids, as interactions can occur. Always inform your doctor about all other medications, supplements, or herbal products you are currently taking.

What precautions should be taken while using Ibugesic Plus Tablet?

Always take the tablet with food or milk to reduce the risk of stomach irritation. Avoid consuming alcohol while on this medication, as it significantly increases the risk of liver damage and gastrointestinal bleeding. Inform your doctor if you have a history of stomach ulcers, liver or kidney conditions, asthma, heart disease, high blood pressure, or fluid retention. Do not exceed the recommended dose or duration of treatment. It is not suitable for children under 12 years of age or those weighing less than 40 kg.

What happens if a dose of Ibugesic Plus Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should Ibugesic Plus Tablet be stored?

Ibugesic Plus Tablet should be stored in a cool and dry place, protected from direct sunlight and moisture. The ideal storage temperature is typically between 20°C to 25°C or below 30°C. Always keep this medicine out of the sight and reach of children.