Cidmus 200 Mg Tablet (7 Tab)

CIDMUS 200 MG Tablet

CIDMUS 200 MG Tablet, manufactured by Dr. Reddy's Laboratories Ltd., is a combination medication primarily used for the management of chronic heart failure.

Composition

Each CIDMUS 200 MG Tablet contains two active ingredients:

• Sacubitril: 97 mg
• Valsartan: 103 mg

This combination belongs to a class of medicines known as angiotensin receptor neprilysin inhibitors (ARNIs). Sacubitril works by inhibiting an enzyme called neprilysin, which helps relax blood vessels, increase sodium excretion, and decrease blood volume. Valsartan is an angiotensin II receptor blocker (ARB) that blocks the action of angiotensin II, a hormone that constricts blood vessels, thereby helping to relax blood vessels and reduce blood pressure.

Uses

CIDMUS 200 MG Tablet is prescribed for:

• Managing symptomatic chronic heart failure in adults with reduced ejection fraction (NYHA Class II-IV).
• Managing symptomatic heart failure with systemic left ventricular systolic dysfunction in pediatric patients aged one year and older. It helps to improve heart function, reduce the workload on the heart, ease symptoms, and decrease the risk of hospitalization and death due to heart failure.

Dosage and Administration

CIDMUS 200 MG Tablet should be taken exactly as prescribed by your doctor.

• It can be taken with or without food.
• Swallow the tablet whole with a glass of water; do not chew, crush, or break it.
• Take it at the same time each day to maintain a consistent level of the medicine in your body.
• Do not exceed the recommended dose.

Side Effects

Common side effects may include:

• Low blood pressure (hypotension), which can cause dizziness or light-headedness.
• High potassium levels in the blood (hyperkalaemia).
• Cough.
• Dizziness.
• Decreased renal function or kidney failure.
• Headache.
• Nausea, stomach pain, diarrhea.
• Tiredness or weakness.

Serious side effects, though rare, can include severe allergic reactions such as swelling of the face, lips, tongue, or throat (angioedema), which requires immediate medical attention.

Precautions

• Pregnancy and Breastfeeding: CIDMUS 200 MG Tablet is contraindicated during pregnancy, especially after the first trimester, as it can harm the fetus. It is not recommended for use in breastfeeding women.
• Alcohol: Caution is advised when consuming alcohol as it may increase dizziness.
• Liver and Kidney Impairment: Patients with moderate liver problems or severe kidney impairment may require dose adjustments and should use this medication with caution.
• Driving and Operating Machinery: Due to potential dizziness, avoid driving or operating heavy machinery until you know how the medication affects you.
• Drug Interactions:
  • Avoid taking with ACE inhibitors (e.g., enalapril, lisinopril) within 36 hours of the last dose, as it can increase the risk of hyperkalaemia and angioedema.
  • Potassium-sparing diuretics (e.g., spironolactone) can increase blood potassium levels.
  • NSAIDs (e.g., ibuprofen, naproxen) may reduce the blood pressure-lowering effects of CIDMUS.
  • Avoid concurrent use with aliskiren if you have diabetes due to increased risks of kidney damage, low blood pressure, and hyperkalaemia.
• Angioedema: Do not take if you have a history of angioedema related to previous ARB or ACE inhibitor therapy.
• Potassium Levels: Regular monitoring of blood potassium levels is recommended, and potassium supplements or potassium-rich foods should be avoided unless advised by a doctor.

Storage

Store CIDMUS 200 MG Tablet at room temperature, ideally below 30°C. Keep it in its original packaging to protect it from moisture and sunlight. Always keep this medicine out of the sight and reach of children.

atient Information: CIDMUS 200 MG TABLET (7 TAB)

What is CIDMUS 200 MG TABLET used for?

CIDMUS 200 MG TABLET is primarily used to treat heart failure in adults and children above one year of age. It helps to reduce the risk of death and hospitalization in adults with chronic heart failure by enabling the heart to pump blood more efficiently.

How does CIDMUS 200 MG TABLET work?

CIDMUS 200 MG TABLET is a combination of two medicines: sacubitril and valsartan. Sacubitril works by inhibiting an enzyme called neprilysin, which leads to increased levels of natural substances that relax blood vessels and promote sodium excretion. Valsartan is an angiotensin II receptor blocker (ARB) that blocks the action of a hormone that constricts blood vessels. Together, these actions relax and widen blood vessels, making it easier for the heart to pump blood throughout the body and reducing its workload.

What is the usual dosage for CIDMUS 200 MG TABLET?

The dosage of CIDMUS 200 MG TABLET is determined by your doctor and can vary based on your medical condition and response to treatment. It should be taken as prescribed, swallowed whole with a glass of water, and not chewed, crushed, or broken. It can be taken with or without food, preferably at the same time each day for consistent effects.

What are the possible side effects of CIDMUS 200 MG TABLET?

Common side effects may include low blood pressure (hypotension), high potassium levels in the blood (hyperkalemia), cough, dizziness, nausea, diarrhea, headache, and weakness or tiredness. Some serious, though rare, side effects can include severe allergic reactions like swelling of the face, lips, tongue, or throat (angioedema), which requires immediate medical attention.

Is CIDMUS 200 MG TABLET safe during pregnancy or breastfeeding?

CIDMUS 200 MG TABLET is not recommended for use during pregnancy, especially after the first three months, as it can cause serious harm to the developing baby. It is also not recommended for use while breastfeeding, as the drug may pass into breast milk and harm the baby. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can CIDMUS 200 MG TABLET be taken with other medications?

CIDMUS 200 MG TABLET can interact with several medications. It should not be taken with ACE inhibitors (e.g., enalapril, lisinopril) and you should wait at least 36 hours after taking an ACE inhibitor before starting CIDMUS 200 MG TABLET. Concomitant use with aliskiren, potassium-sparing diuretics (e.g., spironolactone), potassium supplements, or NSAIDs (e.g., ibuprofen, naproxen) should be avoided or used with caution, as they can increase the risk of side effects like high potassium levels or reduced blood pressure-lowering effects. It may also interact with lithium, sildenafil, and certain statins. Always inform your doctor about all medications, supplements, and herbal preparations you are currently taking.

What precautions should be taken while taking CIDMUS 200 MG TABLET?

Precautions include monitoring for symptoms of low blood pressure, such as dizziness; rising slowly from a sitting or lying position can help. Regular monitoring of blood pressure, kidney function, and potassium levels is important. Caution is advised for patients with kidney or liver disease, as dose adjustments may be needed. Alcohol consumption should be limited or avoided as it can increase dizziness. Do not drive or operate heavy machinery if you experience dizziness or tiredness. Patients with a history of angioedema should avoid this medicine.

What happens if a dose of CIDMUS 200 MG TABLET is missed?

If you miss a dose of CIDMUS 200 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should CIDMUS 200 MG TABLET be stored?

CIDMUS 200 MG TABLET should be stored in a cool and dry place, ideally below 30°C, away from direct sunlight and moisture. Keep it in its original packaging and out of the sight and reach of children and pets. Do not use the medicine after its expiry date.