Macsita M Xr 100/500 Mg Tablet ( 10 Tab )

MACSITA M XR 100/500 MG TABLET

Name:

• Brand Name: MACSITA M XR 100/500 MG TABLET
• Common Name: Sitagliptin and Metformin Extended-Release Tablets

Composition:

• Active Ingredients: Each extended-release tablet contains Sitagliptin 100 mg and Metformin 500 mg.

Uses: MACSITA M XR 100/500 MG TABLET is prescribed for the management of high blood sugar levels in adults with Type 2 Diabetes Mellitus. It is used as an adjunct to diet and exercise to improve glycemic control. The medication helps prevent serious complications of diabetes, such as kidney damage, blindness, nerve problems, limb amputations, heart attacks, and strokes.

Dosage and Administration: This medicine should be taken orally, preferably with meals, as directed by a healthcare professional, to reduce the likelihood of an upset stomach. It is crucial to swallow the tablet whole with water and not to chew, crush, or break it. The dosage and duration of treatment will vary based on individual blood sugar levels, condition, and other concurrent medications. It is typically taken at the same time each day for optimal benefits.

Side Effects:

• Common Side Effects: Diarrhea, nausea, vomiting, upset stomach, headache, sore throat, upper respiratory tract infection (e.g., nasopharyngitis), decreased appetite, abdominal bloating, constipation, flatulence, metallic taste in the mouth, and joint pain.
• Serious Side Effects: Hypoglycemia (low blood sugar), especially when combined with other diabetes treatments like insulin or sulfonylurea, and a rare but serious condition called lactic acidosis. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, difficulty breathing, and stomach pain.

Precautions: Inform your doctor about any history of kidney, liver, or heart diseases, pancreatic issues, or alcohol consumption. It is not recommended for patients with Type 1 diabetes, severe kidney or liver disease, congestive heart failure, lactic acidosis, or diabetic ketoacidosis. Regular monitoring of kidney function and blood sugar levels is advised during treatment. Pregnant or breastfeeding individuals should consult their doctor before use. Avoid or limit alcohol consumption as it may increase the risk of certain side effects and can lower blood glucose.

Storage: Store in a cool and dry place, away from direct sunlight and moisture. Keep out of sight and reach of children. The recommended storage temperature is below 30°C.

What is MACSITA M XR 100/500 MG TABLET used for?

MACSITA M XR 100/500 MG TABLET is primarily used to manage high blood sugar levels in adults with Type 2 diabetes mellitus. It is typically prescribed alongside a healthy diet and regular exercise to help achieve better glycemic control and prevent serious complications associated with diabetes, such as kidney damage, blindness, nerve problems, heart attacks, and strokes.

How does MACSITA M XR 100/500 MG TABLET work?

This medicine is a combination of two active ingredients: Sitagliptin (100mg) and Metformin (500mg). Sitagliptin works by increasing the levels of certain natural substances (incretin hormones) that help the pancreas produce more insulin when blood sugar is high and decrease the amount of sugar produced by the liver. Metformin, a biguanide, reduces glucose production in the liver, decreases the absorption of sugar from the intestines, and improves the body's sensitivity to insulin, helping cells utilize blood glucose more effectively. Together, these actions help to control both fasting and post-meal blood sugar levels.

What is the usual dosage for MACSITA M XR 100/500 MG TABLET?

The dosage of MACSITA M XR 100/500 MG TABLET will be determined by your doctor based on your specific condition, blood sugar levels, and other medications you may be taking. It is important to take the tablet whole with food, usually at the same time each day, to reduce the likelihood of an upset stomach and ensure maximum effectiveness. Do not chew, crush, or break the tablet.

What are the possible side effects of MACSITA M XR 100/500 MG TABLET?

Common side effects may include diarrhea, nausea, vomiting, upset stomach, headache, sore throat, and upper respiratory tract infections. Low blood sugar levels (hypoglycemia) are also a possible side effect, especially if taken with other diabetes medications like insulin or sulfonylureas. Rare but serious side effects can include lactic acidosis (an excess of lactic acid in the blood) and, with long-term use, vitamin B12 deficiency.

Is MACSITA M XR 100/500 MG TABLET safe during pregnancy or breastfeeding?

It is generally not recommended for use during pregnancy or breastfeeding. Limited human data suggest the drug may pass into breast milk and potentially harm the baby, and animal studies have shown harmful effects on the developing baby. Always consult your doctor before taking this medication if you are pregnant, planning a pregnancy, or breastfeeding.

Can MACSITA M XR 100/500 MG TABLET be taken with other medications?

Yes, but caution is advised as it can interact with certain medicines. Inform your doctor about all current medications, supplements, or herbal products you are taking. Interactions can occur with other antidiabetic medicines (increasing the risk of hypoglycemia), certain cationic medicines (e.g., amiloride, digoxin, morphine), diuretics (e.g., furosemide, hydrochlorothiazide, increasing the risk of lactic acidosis), corticosteroids, and oral contraceptives.

What precautions should be taken while using MACSITA M XR 100/500 MG TABLET?

Before starting this medicine, inform your doctor if you have a history of kidney, liver, or heart disease, pancreatic issues, severe infections, or recent dehydration. Alcohol consumption should be avoided or limited as it can increase the risk of lactic acidosis and hypoglycemia. Regular monitoring of kidney function and blood sugar levels is often recommended during treatment. Do not stop taking the medication without consulting your doctor, even if you feel better.

What happens if a dose of MACSITA M XR 100/500 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should MACSITA M XR 100/500 MG TABLET be stored?

MACSITA M XR 100/500 MG TABLET should be stored at room temperature, typically not exceeding 30°C. Keep it in its original container, away from direct light and moisture, and out of the reach of children and pets. Always check the expiry date before use.