Clofert 50

CLOFERT 50 by MANEESH HEALTHCARE: Detailed Product Description

---

Name

• Brand Name: CLOFERT 50
• Common Name: Clomiphene Citrate
• Manufacturer: Maneesh Healthcare / Maneesh Pharmaceuticals Ltd.

Composition

CLOFERT 50 contains 50 mg of Clomiphene Citrate as its active ingredient.

Uses

CLOFERT 50 is an ovulation stimulant primarily used to treat female infertility. It is prescribed for women who have difficulty conceiving due to problems with ovulation, including those diagnosed with Polycystic Ovary Syndrome (PCOS). The medication works by stimulating the release of hormones necessary for the development and release of mature eggs from the ovaries, thereby enhancing the chances of pregnancy.

Dosage and Administration

The dosage and duration of CLOFERT 50 are determined by a healthcare professional based on the patient's condition.

• Typical Course: Usually taken once daily for 5 days, often starting on the 5th day of the menstrual cycle.
• Administration: Swallow the tablet whole with a glass of water; do not crush or chew it. It can be taken with or without food, but it is recommended to take it at the same time each day for optimal effectiveness.
• Treatment Cycles: The initial course typically involves one 50 mg tablet daily for five days. If necessary, the dose may be increased to 100 mg daily for subsequent courses, as early as 30 days after the previous therapy. Treatment is generally limited to a maximum of six cycles, as prolonged usage may not be safe.

Side Effects

Common Side Effects:

• Nausea, vomiting, bloating
• Headache, dizziness, tiredness
• Hot flashes (flushing)
• Breast discomfort or pain
• Ovarian enlargement
• Irregular menstrual bleeding, heavy periods, or spotting
• Lower stomach pain, abdominal pain with weight gain

Serious Side Effects (Seek immediate medical attention if experienced):

• Severe pelvic pain
• Vision problems such as blurred vision, visual disturbances, or blind spots
• Signs of Ovarian Hyperstimulation Syndrome (OHSS), including severe abdominal pain, nausea, difficulty breathing, enlarged ovaries, or fluid build-up in the chest or abdomen
• Allergic reactions (rash, itching, swelling)
• Signs of stroke
• Liver problems (e.g., yellowing of skin and eyes)

Precautions

• Pregnancy and Breastfeeding: CLOFERT 50 is not recommended during pregnancy; a negative pregnancy test must be confirmed before starting treatment. It is also not recommended for breastfeeding women, as it may affect milk production.
• Allergies: Do not take if allergic to Clomiphene Citrate or any other ingredients.
• Contraindications/Caution:
  • Patients with liver disease, unexplained vaginal bleeding, hormone-sensitive cancers, early menopause, or existing ovarian cysts (excluding polycystic ovaries) should avoid this medication.
  • Caution is advised for individuals with kidney problems, a history of fits or seizures, uterine fibroids, high blood fat levels (hyperlipidaemia), thyroid/adrenal gland disorders, or pituitary gland/brain tumors.
• Alcohol: Avoid consuming alcohol while on this medication.
• Driving/Operating Machinery: CLOFERT 50 can cause blurred vision; therefore, avoid driving or operating heavy machinery if you experience visual disturbances.
• Monitoring: Regular medical monitoring, including ultrasounds and blood tests, is crucial during treatment to track ovulation and manage potential side effects.
• Multiple Pregnancies: The use of CLOFERT 50 may increase the risk of multiple pregnancies.
• Drug Interactions: Inform your doctor about all other medications, supplements, or herbal products you are currently taking to avoid potential interactions.
• Pediatric Use: This medication is not intended for use in children or adolescents under 18 years of age.

Storage

• Store in a cool and dry place, away from direct sunlight.
• Keep out of sight and reach of children.
• Maintain storage temperatures below 25°C or between 15-30°C, in an airtight container.

CLOFERT 50 by MANEESH HEALTHCARE is a medication containing Clomiphene Citrate, primarily used to treat female infertility. It acts as an ovulation stimulator, helping women who have difficulty ovulating to conceive.

Here are some frequently asked questions about CLOFERT 50:

What is CLOFERT 50 used for?

CLOFERT 50 is used in the management of female infertility, particularly for women who experience ovulation problems or have Polycystic Ovary Syndrome (PCOS). It helps to promote ovulation, which is the release of a matured egg from the ovaries.

How does CLOFERT 50 work?

CLOFERT 50 contains Clomiphene Citrate, which is an ovulation stimulator and a Selective Estrogen Receptor Modulator (SERM). It works by stimulating the pituitary gland to release essential hormones, Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH), which are crucial for the growth and release of a mature egg from the ovary.

What is the usual dosage of CLOFERT 50?

Typically, the recommended dosage is 50 mg taken once daily for 5 days. Treatment usually starts on the 5th day of the menstrual period, or at any time if there is no menstrual period. The dose may be increased to 100 mg per day for a second course, if necessary, as early as 30 days after the previous therapy, with a maximum of six treatment cycles. It should be swallowed whole with water and taken as advised by your physician, preferably at the same time each day.

What are the possible side effects of CLOFERT 50?

Common side effects can include flushing (reddening of the face), lower stomach pain, nausea, vomiting, painful periods, heavy bleeding, painful breasts, bloating, headache, enlarged ovaries, hot flashes, irregular menstrual bleeding, tiredness, and dizziness. More severe side effects, though rare, can include signs of Ovarian Hyperstimulation Syndrome (OHSS) like severe abdominal pain with weight gain, difficulty breathing, or allergic reactions such as skin rash or swelling. Blurred vision, visual spots, or flashes may also occur.

Is CLOFERT 50 safe during pregnancy or breastfeeding?

No, CLOFERT 50 should not be used during pregnancy after successful conception, as it is considered highly unsafe and may cause harmful effects to the developing baby. A negative pregnancy test should be confirmed before initiating treatment. It is also not recommended during breastfeeding because it may pass into breast milk, potentially harming the baby, and can decrease milk production.

Can CLOFERT 50 be taken with other medications?

You should inform your doctor about all other medicines, supplements, or herbal remedies you are currently taking or plan to take. CLOFERT 50 can interact with other medications, potentially affecting their efficacy or increasing the risk of side effects.

What precautions should be taken while using CLOFERT 50?

Do not take CLOFERT 50 if you are allergic to Clomiphene Citrate or any of its ingredients. It is also contraindicated if you have liver disease, ovarian cysts (other than polycystic ovaries), unexplained vaginal bleeding, hormone-sensitive cancers, or have experienced early menopause. Exercise caution and inform your doctor if you have kidney problems, a history of fits or seizures, high blood fat levels (hypertriglyceridemia), or uterine fibroids. Regular monitoring through blood tests and ultrasounds is crucial during treatment. Alcohol consumption should be avoided as it may worsen conditions or side effects. As it may cause blurred vision, avoid driving or operating heavy machinery if your vision is affected. This medicine is not for use in children, adolescents under 18, men, or post-menopausal women.

What happens if a dose of CLOFERT 50 is missed?

If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. It is advisable to consult your doctor if a dose is missed, as it might impact the effectiveness of your treatment.

How should CLOFERT 50 be stored?

CLOFERT 50 should be stored in a cool, dry place away from direct light, maintaining a temperature below 25°C or between 15-30°C. Keep the medicine out of sight and reach of children and pets, and do not use it after its expiry date.