VINICOR D 25 MG TABLET

Name

Brand Name: VINICOR D 25 MG TABLET Common Name: Metoprolol Succinate and Chlorthalidone Tablets

Composition

VINICOR D 25 MG TABLET contains two active ingredients:

• Metoprolol Succinate (25 mg)
• Chlorthalidone (6.25 mg)

Metoprolol is a beta-blocker that works by blocking epinephrine, which helps to decrease heart rate and blood pressure. Chlorthalidone is a diuretic ("water pill") that expels excess water and salt from the body, reducing fluid accumulation and edema.

Uses

VINICOR D 25 MG TABLET is primarily used for the treatment of:

• Hypertension (high blood pressure), especially when a single medication is not effective.
• It also helps to reduce the risk of future heart attacks and strokes in hypertensive patients.
• The medicine can also reduce edema (fluid retention) in hypertensive patients. Some sources also indicate its use in managing heart failure, angina (heart-related chest pain), improving survival after a heart attack, migraine prevention, essential tremor, and management of anxiety or hyperthyroidism symptoms.

Dosage and Administration

VINICOR D 25 MG TABLET should be taken orally as prescribed by your doctor. The dosage and frequency depend on the specific condition and individual response. It is typically taken once daily, preferably in the morning to avoid frequent urination at night. The tablet can be taken with or without food, but taking it with food might help if stomach upset occurs. Swallow the tablet whole with a glass of water; do not crush, break, or chew it. Do not stop taking this medicine abruptly, as it can lead to a sudden rise in blood pressure, increasing the risk of heart attack and stroke.

Side Effects

Common side effects may include:

• Nausea, vomiting, diarrhea, constipation
• Fatigue, dizziness, headache
• Slow heart rate (bradycardia)
• Orthostatic hypotension (dizziness on standing)
• Loss of appetite (anorexia)
• Visual abnormality, blurred vision
• Photosensitivity (sensitivity to light)
• Weakness, restlessness
• Stomach pain
• Electrolyte imbalances (decreased potassium, sodium, magnesium, increased uric acid, increased calcium levels)
• Cold extremities
• Impotence, decreased libido

Serious side effects that require immediate medical attention may include severe abdominal pain, yellowing of the skin or eyes (jaundice), skin rash, itching, swelling (especially of the face, tongue, or throat), difficulty breathing, changes in heart rhythm, very low blood pressure, fainting, heart failure, and depression.

Precautions

• Allergies: Do not take if allergic to any of its components.
• Heart Conditions: Avoid use in patients with heart rhythm problems, heart failure, blocked blood vessels, severe bradycardia, cardiogenic shock, or untreated pheochromocytoma. Use with caution in patients with a history of heart attack, chest pain (angina pectoris), or heart surgery.
• Kidney and Liver Diseases: Use with caution in patients with kidney or liver diseases; dose adjustments and regular monitoring of kidney and liver function, as well as electrolyte levels, may be necessary.
• Diabetes: Caution is advised in diabetic patients as it may mask symptoms of low blood sugar. Regular monitoring of blood sugar levels is recommended.
• Pregnancy and Breastfeeding: Vinicor D may be unsafe during pregnancy and should only be taken if advised by a doctor due to potential severe side effects. It passes into breast milk in small quantities, so consult your doctor before use during breastfeeding.
• Driving and Alcohol: This medicine may cause dizziness, drowsiness, or blurred vision. Avoid driving or operating heavy machinery if these symptoms occur. Alcohol consumption is not recommended as it can intensify side effects like dizziness and low blood pressure.
• Other Conditions: Use with caution in patients with asthma, chronic obstructive pulmonary disease (COPD), gout, lupus, thyroid conditions, or circulation issues. It may cause dehydration, so drink plenty of fluids.
• Drug Interactions: Inform your doctor about all current medications, including supplements, as interactions can occur with mood stabilizers (e.g., lithium), antidepressants (e.g., fluoxetine), calcium channel blockers (e.g., verapamil, diltiazem), and NSAIDs (e.g., ibuprofen).

Storage

Store VINICOR D 25 MG TABLET below 25°C. Protect it from light and moisture. Keep it out of the sight and reach of children and pets. Do not use the medication if it has expired.

What is VINICOR D 25 MG TABLET used for?

VINICOR D 25 MG TABLET is primarily used to treat hypertension (high blood pressure). It helps to control blood pressure, especially when a single medication is not sufficient. By effectively managing high blood pressure, it also aids in reducing the risk of serious health complications such as heart attacks and strokes. Additionally, it can help reduce fluid retention and oedema (swelling of legs and hands) in hypertensive patients.

How does VINICOR D 25 MG TABLET work?

VINICOR D 25 MG TABLET is a combination of two active ingredients: Metoprolol and Chlorthalidone. Metoprolol is a beta-blocker that works by blocking epinephrine, a hormone that can increase heart rate and blood pressure, leading to a decrease in heart rate and blood pressure. Chlorthalidone is a diuretic, also known as a "water pill," which acts by expelling excess water and salt from the body, thereby reducing fluid accumulation and oedema.

What is the usual dosage of VINICOR D 25 MG TABLET?

The dosage of VINICOR D 25 MG TABLET should be taken exactly as prescribed by your doctor. It is typically taken once daily, preferably with food, to ensure consistent absorption and effectiveness. Do not crush, break, or chew the tablet. Your doctor will determine the appropriate dosage and frequency based on your individual condition and response to the medicine.

What are the possible side effects of VINICOR D 25 MG TABLET?

Common side effects may include fatigue, dizziness, headache, slow heart rate (bradycardia), nausea, vomiting, diarrhoea, constipation, and stomach pain. It may also cause electrolyte imbalances such as decreased potassium and sodium levels, and increased blood uric acid. Less common but serious side effects can include severe dizziness, very slow or irregular heartbeat, shortness of breath, confusion, fainting, and allergic reactions. If any side effects persist or worsen, consult your doctor immediately.

Is VINICOR D 25 MG TABLET safe during pregnancy or breastfeeding?

VINICOR D 25 MG TABLET is generally not recommended during pregnancy unless clinically required and when the benefits outweigh the potential risks, as animal studies have shown harmful effects on the developing baby. It may be unsafe to use during pregnancy. For breastfeeding mothers, caution is advised as it can pass into breast milk in small amounts. It should be given to breastfeeding mothers only if clinically needed, and it is recommended to consult your doctor before using this medicine while breastfeeding.

Can VINICOR D 25 MG TABLET be taken with other medications?

VINICOR D 25 MG TABLET can interact with various medications. For example, chlorthalidone may increase the toxicity of mood stabilizers like lithium. Antidepressants like fluoxetine can increase metoprolol levels. Taking it with certain calcium channel blockers (e.g., verapamil, diltiazem) may increase the risk of slow heartbeat. NSAIDs (e.g., ibuprofen) may reduce its blood pressure-lowering effect. Always inform your doctor about all medications, supplements, or herbal remedies you are currently taking to avoid potential interactions.

What precautions should be taken while using VINICOR D 25 MG TABLET?

• Driving and Operating Machinery: This medicine may cause dizziness, drowsiness, or lightheadedness. Avoid driving or operating heavy machinery if you experience these symptoms.
• Alcohol: Consumption of alcohol is not recommended as it can intensify side effects like dizziness and lightheadedness and affect blood pressure control.
• Pre-existing Conditions: Use with caution in patients with severe liver or kidney diseases, diabetes, gout, asthma, heart rhythm problems, or low blood pressure. Regular monitoring of blood pressure, electrolyte levels, and blood sugar may be necessary.
• Abrupt Withdrawal: Do not stop taking this medicine suddenly without consulting your doctor, as it can cause a sudden rise in blood pressure, increasing the risk of heart attack and stroke.
• Photosensitivity: It may cause sensitivity to light, so prolonged exposure to sunlight should be avoided.

What happens if a dose of VINICOR D 25 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one without consulting your doctor.

How should VINICOR D 25 MG TABLET be stored?

Store VINICOR D 25 MG TABLET below 25°C, protected from light and moisture. Keep it out of the sight and reach of children and pets.