Admenta 5 Mg Tablet (10 Tab)

ADMENTA 5 MG TABLET by SUN PHARMA LABORATORIES LTD.

Name

• Brand Name: ADMENTA 5 Tablet, ADMenta 5 Tablet
• Common Name: Memantine

Composition

• Active Ingredient: Memantine Hydrochloride 5 mg

Uses

ADMENTA 5 Tablet is primarily prescribed for the management of moderate to severe Alzheimer's disease. It helps improve cognitive functions such as memory, thinking, and the ability to perform daily activities by restoring the balance of chemicals in the nerves. This medication can help reduce symptoms like forgetfulness, confusion, impaired reasoning, and difficulty in understanding, thereby improving the overall quality of life for patients.

Dosage and Administration

It is crucial to follow the doctor's instructions for dosage and duration. ADMENTA 5 Tablet can be taken with or without food, but it is recommended to take it at a fixed time each day to maintain a consistent level of the medicine in the bloodstream. The tablet should be swallowed whole without crushing or breaking it. The typical initial dosage is 5 mg once daily in the morning for the first week, with weekly increases in steps of 5 mg. The maximum recommended dose is 20 mg daily. Doses greater than 10 mg/day should be given in two divided doses. Do not stop taking the medicine abruptly without consulting your doctor.

Side Effects

Common side effects of ADMENTA 5 Tablet may include:

• Headache
• Dizziness
• Sleepiness or drowsiness
• Constipation
• Confusion
• Balance disorders
• Vomiting and Nausea
• Diarrhea
• Elevated blood pressure
• Tiredness

If these side effects persist or worsen, consult your doctor.

Precautions

• Pregnancy and Breastfeeding: Consult a doctor before using this medication if pregnant or breastfeeding.
• Alcohol: Avoid consuming alcohol as it may increase side effects such as dizziness and sleepiness.
• Liver and Kidney Disease: Use with caution in patients with liver or kidney problems; dose adjustments may be necessary.
• Driving and Operating Machinery: ADMENTA 5 Tablet may cause dizziness and sleepiness. Avoid driving or operating machinery until you know how the medicine affects you.
• Other Conditions: Inform your doctor if you have a history of seizures, heart problems, or have made sudden changes to your diet.
• Drug Interactions: Inform your doctor about all other medications, supplements, or herbal products you are taking. It may interact with medicines such as amantadine, dextromethorphan, certain muscle relaxants (e.g., dantrolene, baclofen), stomach ulcer medications (e.g., cimetidine, ranitidine), anti-arrhythmics (e.g., quinidine, procainamide, amiodarone, flecainide), and diuretics (e.g., hydrochlorothiazide).

Storage

Store ADMENTA 5 Tablet at room temperature, around 25°C, away from light and moisture. Keep it out of the reach of children and do not use it after the expiry date.

ADMENTA 5 MG TABLET (10 TAB) contains memantine, a medication used to treat moderate to severe Alzheimer's disease.

What is ADMENTA 5 MG TABLET used for?

ADMENTA 5 MG TABLET is used for the management of moderate to severe dementia associated with Alzheimer's disease. It helps to improve awareness, memory, and the ability to perform daily tasks by reducing symptoms, but it does not cure or slow the underlying progression of Alzheimer's disease.

How does ADMENTA 5 MG TABLET work?

The active ingredient, memantine, works as an N-methyl-D-aspartate (NMDA) receptor antagonist. In Alzheimer's disease, excessive activation of NMDA receptors by the brain chemical glutamate can lead to neuronal damage and cognitive symptoms. Memantine helps by blocking the effects of this excessive glutamate activity, thereby decreasing abnormal activity in the brain and providing neuroprotective benefits.

What is the usual dosage for ADMENTA 5 MG TABLET?

For immediate-release tablets, the recommended initial adult dosage is typically 5 mg once daily. The dosage is usually increased gradually in 5 mg increments at weekly intervals, as tolerated, to a target maintenance dose of 20 mg per day, often administered as 10 mg twice daily. Your doctor will determine the appropriate dosing schedule.

What are the possible side effects of ADMENTA 5 MG TABLET?

Common side effects may include dizziness, headache, confusion, constipation, and drowsiness. Other possible side effects include diarrhea, aggression, depression, nausea, vomiting, rapid weight gain, and back pain. Serious but less common side effects can include severe allergic reactions, seizures, changes in mental status, hepatitis, pancreatitis, or heart failure. If any side effects persist or worsen, you should contact your healthcare provider.

Is ADMENTA 5 MG TABLET safe during pregnancy or breastfeeding?

Memantine is generally not recommended during pregnancy as there is insufficient data on its effects in pregnant women. Animal studies have shown some adverse developmental effects at doses higher than the maximum recommended human dose. It is also not known if memantine passes into breast milk. Therefore, it is important to discuss with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can ADMENTA 5 MG TABLET be taken with other medications?

Memantine can interact with certain other medications. It should be used with caution with other NMDA antagonists such as amantadine, ketamine, and dextromethorphan, as combining them may increase neuropsychiatric side effects. Medications that make the urine alkaline (e.g., sodium bicarbonate, carbonic anhydrase inhibitors) can decrease the elimination of memantine from the body, potentially leading to increased drug levels and a higher risk of side effects. Always inform your doctor about all prescription, over-the-counter, vitamin, and herbal supplements you are taking.

What precautions should be taken while taking ADMENTA 5 MG TABLET?

Use ADMENTA 5 MG TABLET with caution if you have kidney or liver disease, a seizure disorder, or conditions that increase your urine pH (like severe urinary tract infections or certain dietary changes). Since this medication can cause dizziness and confusion, you should avoid driving or operating machinery until you know how it affects you. Alcohol consumption may also increase the risk of dizziness or confusion while taking this medication.

What happens if a dose of ADMENTA 5 MG TABLET is missed?

If you miss a dose of ADMENTA 5 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss several doses in a row, contact your doctor before restarting the medication.

How should ADMENTA 5 MG TABLET be stored?

ADMENTA 5 MG TABLET should be stored in a closed container at room temperature, typically between 68°F to 77°F (20°C to 25°C). Keep the medication away from excessive heat, moisture, and direct light. It is important to keep all medicines out of the reach of children. Do not keep outdated medicine or medicine that is no longer needed; consult your healthcare professional on how to dispose of unused medication.