Tentide Af 25mg Tab

TENTIDE AF 25MG TABLET

TENTIDE AF 25mg Tablet is an antiviral medication manufactured by SUN PHARMA-SYGNUS DIV.

• Composition TENTIDE AF 25mg Tablet contains Tenofovir Alafenamide (25mg) as its active ingredient. This compound is a prodrug that is converted within liver cells to its active form, tenofovir diphosphate, which blocks the virus's ability to multiply.

• Uses TENTIDE AF 25mg Tablet is primarily used in the treatment of:

  • Chronic Hepatitis B Virus (HBV) infection: It prevents the multiplication of the virus in human cells, thereby reducing the viral load and minimizing liver damage.
  • HIV infection: In HIV-positive individuals, it is used to decrease the amount of HIV virus in the body, improving immunity and reducing the risk of complications, typically alongside other antiretroviral medications.

• Dosage and Administration The typical dosage is one tablet (25mg) taken orally once daily with food. The tablet should be swallowed whole and not chewed, crushed, or broken. Consistency in timing is recommended for optimal effectiveness.

• Side Effects Common side effects may include:

  • Headache, dizziness, fatigue, weakness
  • Nausea, vomiting, diarrhea, abdominal pain, indigestion
  • Rash, itching
  • Cough, back pain, joint pain
  • Electrolyte imbalance

  Serious side effects, though rare, can include lactic acidosis (a buildup of lactic acid in the body), hepatomegaly (enlarged liver), and kidney damage. If severe or unusual side effects occur, medical attention should be sought immediately.

• Precautions

  • Allergies: Do not take if allergic to Tenofovir Alafenamide.
  • Kidney and Liver Conditions: Use with caution in patients with kidney disease, as dose adjustment may be necessary. While it's generally considered safe for liver disease, consultation with a doctor is advised.
  • Pregnancy and Breastfeeding: Not recommended during pregnancy or breastfeeding, as the medication may pass to the baby.
  • Alcohol Interaction: Avoid alcohol consumption as it can increase side effects such as dizziness and liver damage.
  • Driving: This medication may cause dizziness, headache, or fatigue; avoid driving or operating heavy machinery if affected.
  • Drug Interactions: Inform your doctor about all current medications, as some drugs (e.g., rifampin, St. John's Wort) can interact with TENTIDE AF.
  • HIV/HBV Transmission: TENTIDE AF 25mg Tablet does not prevent the transmission of HIV or HBV. Patients should continue safe practices to prevent spreading the virus.
  • Monitoring: Regular blood tests are recommended to monitor for potential complications, especially for kidney function and viral load.

• Storage Store TENTIDE AF 25mg Tablet below 30°C. It should be kept away from moisture, heat, and light, and should not be frozen. Keep out of reach of children and pets.

Tentide AF 25MG Tablet is an antiviral medication containing Tenofovir alafenamide, primarily used to manage chronic Hepatitis B virus (HBV) infection and, in some cases, in combination with other antivirals for HIV infection.

What is Tentide AF 25MG Tablet used for?

Tentide AF 25MG Tablet is primarily used to manage chronic Hepatitis B virus (HBV) infection in adults with compensated liver disease. It can also be used in combination with other antiviral medications to treat HIV infection.

How does Tentide AF 25MG Tablet work?

Tentide AF 25MG Tablet contains Tenofovir alafenamide, an antiviral drug that belongs to a class called nucleoside reverse transcriptase inhibitors (NRTIs). It works by inhibiting the HBV reverse transcriptase enzyme, which is crucial for the hepatitis B virus to replicate. By blocking this enzyme, it reduces the amount of virus in the body (viral load) and helps prevent further liver damage.

What is the usual dosage for Tentide AF 25MG Tablet?

The usual dosage is one tablet (25 mg) taken once daily with food. It should be swallowed whole and not crushed, chewed, or broken. Always follow your doctor's instructions regarding dosage and duration.

What are the possible side effects of Tentide AF 25MG Tablet?

Common side effects may include headache, nausea, diarrhea, fatigue, skin rash, joint pain, abdominal pain, and indigestion. More serious, but rare, side effects can include lactic acidosis (a build-up of lactic acid in the blood), severe liver problems (such as an enlarged liver or worsening liver function), and kidney problems or damage.

Is Tentide AF 25MG Tablet safe during pregnancy or breastfeeding?

Tentide AF 25MG Tablet is generally considered safe to use during pregnancy if prescribed by a doctor. Animal studies have shown low or no adverse effects on the developing baby. Similarly, it is probably safe to use during breastfeeding, as limited human data suggests the drug does not represent a significant risk to the baby. However, it is always advised to consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can Tentide AF 25MG Tablet be taken with other medications?

It is important to consult your doctor before combining Tentide AF 25MG Tablet with any other medications to avoid potential interactions. It can interact with certain other antiviral drugs, and specific medications like rifampin or St. John's Wort should be avoided due to potential interactions.

What precautions should be taken while using Tentide AF 25MG Tablet?

Precautions include avoiding alcohol consumption while on this medication. Caution is advised if you have a history of kidney disease, liver problems, osteoporosis, or pancreatitis. Tentide AF 25MG Tablet may cause dizziness, so you should be cautious when driving or operating machinery. Regular blood tests are recommended to monitor liver function, kidney function, and viral load. It is not recommended for children under 12 years of age or those weighing less than 35 kg. This medicine does not cure Hepatitis B and does not prevent its transmission to others.

What happens if a dose of Tentide AF 25MG Tablet is missed?

If you miss a dose, take it as soon as you remember, provided it is within 12 hours of your usual dosing time, and take it with food. If more than 12 hours have passed, or it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one.

How should Tentide AF 25MG Tablet be stored?

Tentide AF 25MG Tablet should be stored in a cool, dry place, ideally not exceeding 30 degrees Celsius, and away from direct sunlight and moisture. Keep the medicine in its original packaging and out of the reach of children. Some sources specify storage between 20°C to 25°C.