Nefrozon Tablet (10 Tab)

NEFROZON TABLET (10 TAB) by MANKIND PHARMA LTD.

Name: Nefrozon Tablet (Brand Name: Nefrozon)

Composition: Each tablet contains a combination of Acetylcysteine (150 mg) and Taurine (500 mg).

Uses: Nefrozon Tablet is primarily prescribed for the management of diabetic nephropathy, a condition where the kidneys are damaged due to diabetes, and chronic kidney disease. It helps protect kidney cells from further damage, reduces the progression of kidney damage, and lowers the risk of kidney failure in individuals with diabetic kidney disease. The medication is also used in managing cases of paracetamol poisoning and radiocontrast-induced kidney damage.

Dosage and Administration: Nefrozon Tablet should be taken orally as prescribed by a doctor. It can be consumed with or without food. The precise dosage and duration of treatment will depend on the patient's specific condition and response to the medication. It is crucial to follow the doctor's instructions carefully and not exceed the suggested dose.

Side Effects: Common side effects may include nausea, vomiting, rash, fever, runny nose, diarrhea, abdominal pain, skin irritation, throat irritation, stomach upset, drowsiness, mouth sores, edema, and flushing. If side effects persist or worsen, medical advice should be sought.

Precautions:

• A prescription is required for Nefrozon Tablet.
• Inform your doctor about any allergies to taurine, acetylcysteine, or other components of the medicine.
• Caution is advised for patients with asthma, stomach ulcers, or liver and kidney issues.
• Pregnant or breastfeeding women should consult their doctor before use.
• Avoid alcohol consumption while taking this medicine.
• The medicine may increase the risk of severe skin rashes like Stevens-Johnson syndrome; discontinue use and seek medical advice if rashes develop.
• It is not suitable for children under 12 or 14 years old depending on the source.

Storage: Store Nefrozon Tablet in a cool and dry place, below 30°C, and away from direct sunlight. Keep it out of sight and reach of children.

NEFROZON TABLET (10 TAB) by MANKIND PHARMA LTD. - Frequently Asked Questions

What is Nefrozon Tablet used for?

Nefrozon Tablet is primarily used to manage diabetic nephropathy, a condition where the kidneys are damaged due to diabetes. It is also used in the treatment of chronic kidney disease (CKD), to slow the progression of kidney damage, and for kidney protection in patients with hypertension. Additionally, it helps in reducing albuminuria associated with kidney diseases and can reduce the risk of end-stage renal disease (ESRD) and kidney failure. Some sources also indicate its use in managing paracetamol poisoning and radiocontrast-induced kidney damage.

How does Nefrozon Tablet work?

Nefrozon Tablet contains two active ingredients: Acetylcysteine (150 mg) and Taurine (500 mg). These ingredients work together to protect the kidneys from damage caused by free radicals and oxidative stress. Acetylcysteine acts as an antioxidant, reducing the production of harmful free radicals and possessing anti-inflammatory properties. Taurine, an amino acid, also has antioxidant properties, helps lower blood glucose levels, and protects against kidney tissue damage. The combination helps slow down the damage to kidney cells and improves kidney function.

What is the usual dosage for Nefrozon Tablet?

Nefrozon Tablet should be taken exactly as prescribed by your doctor. The dosage and duration of treatment can vary significantly based on your specific condition, its severity, and your response to the medication. It can be taken with or without food. Do not exceed the suggested dose or alter the frequency of administration without consulting your doctor.

What are the possible side effects of Nefrozon Tablet?

Common side effects associated with Nefrozon Tablet include nausea, vomiting, and rash. These are generally mild and temporary. Other reported side effects may include headache, dizziness, stomach pain, diarrhea, fever, runny nose, abdominal pain, skin irritation, throat irritation, stomach upset, drowsiness, mouth sores, edema, and flushing. In rare cases, severe skin reactions like Stevens-Johnson syndrome and Lyell syndrome can occur, characterized by severe skin rashes; if these develop, discontinue the medication and seek immediate medical attention. Allergic reactions are also possible.

Is Nefrozon Tablet safe during pregnancy or breastfeeding?

Pregnancy: Nefrozon Tablet is not recommended for use during pregnancy unless clearly advised by a doctor. It is important to consult your doctor, who will assess the potential benefits and risks, as there is limited safety information in humans and animal studies have shown harmful effects on the developing baby.

Breastfeeding: It is advisable to consult your doctor before taking Nefrozon Tablet while breastfeeding. The safe use in breastfeeding mothers has not yet been established, and your doctor will determine if it is safe for both you and your baby.

Can Nefrozon Tablet be taken with other medications?

It is crucial to inform your doctor about all medicines, supplements, or herbal products you are currently taking or plan to take, as some medications can interact with Nefrozon Tablet. Potential drug interactions may occur with blood pressure medications (e.g., ACE inhibitors like lisinopril, angiotensin receptor blockers like losartan), diabetes medications (e.g., metformin, insulin), nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and naproxen, and certain antibiotics (e.g., ciprofloxacin, sulfamethoxazole-trimethoprim). Other medications that may interact include oral contraceptives, steroids, water pills, medicines for heart problems, and some antitussives (cough medicines).

What precautions should be taken while using Nefrozon Tablet?

Nefrozon Tablet requires a prescription for purchase. Before starting treatment, inform your doctor about your complete medical history, including any pre-existing conditions such as asthma, stomach ulcers, liver or kidney diseases, or a known allergy to histamine. Do not take this medicine if you are allergic to Acetylcysteine, Taurine, or any other ingredients. Caution is advised if you have asthma, as it may worsen your condition, and patients will be closely monitored. It is best to avoid consuming alcohol while taking Nefrozon Tablet, as it may cause unwanted side effects. The medication is generally not suitable for children under 12 or 14 years, as its safety and efficacy in this age group have not been established.

What happens if a dose of Nefrozon Tablet is missed?

If you miss a dose of Nefrozon Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should Nefrozon Tablet be stored?

Nefrozon Tablet should be stored in a cool and dry place, protected from direct sunlight, moisture, and heat. It should typically be stored below 30°C. Keep the medicine out of the sight and reach of children.