Corabrad 5mg Tab

CORABRAD 5MG Tablet

Name: CORABRAD 5MG Tablet (Brand Name), Ivabradine (Common Name)

Composition: Each tablet contains Ivabradine 5mg as the active ingredient. Ivabradine is classified as a hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker.

Uses: CORABRAD 5MG Tablet is prescribed for the symptomatic management of stable angina pectoris (heart-related chest pain) in adults, particularly when beta-blockers are not tolerated or are contraindicated, and the heart rate is 70 beats per minute or higher. It is also used to manage chronic heart failure in adult patients with a heart rate of 75 beats per minute or above, often as a combination therapy with beta-blockers or when beta-blockers are unsuitable. It works by slowing the heart rate, thereby reducing the heart's workload and oxygen demand, which improves heart function and reduces angina attacks.

Dosage and Administration: Take CORABRAD 5MG Tablet as advised by your physician, usually 5mg twice daily, preferably with food. Swallow the tablet whole with a glass of water; do not crush or chew it. The doctor will determine the correct dose and duration based on age, body weight, and disease condition.

Side Effects: Common side effects include slow heart rate (bradycardia), brief moments of increased brightness (luminous phenomena), headache, dizziness, blurred vision, and uncontrolled blood pressure. Serious side effects can include atrial fibrillation (irregular rapid heartbeat) and significant changes in heartbeat.

Precautions: CORABRAD 5MG Tablet is not recommended during pregnancy or breastfeeding. It should be used with caution in patients with severe kidney or liver disease, low blood pressure, or certain heart rhythm disorders. Avoid driving or operating machinery if you experience temporary vision disturbances or dizziness. Inform your doctor about all other medications you are taking, as interactions can occur with drugs like certain antifungals, antibiotics, HIV medications, and other cardiac medicines. Alcohol consumption should be avoided as it can increase the risk of dizziness and low blood pressure.

Storage: Store CORABRAD 5MG Tablet at room temperature, protected from moisture and light, ideally below 30°C. Keep it out of sight and reach of children.

What is CORABRAD 5MG Tablet used for?

CORABRAD 5MG Tablet, containing the active ingredient Ivabradine, is primarily used for the symptomatic management of chronic stable angina (heart-related chest pain) and chronic heart failure. It helps to reduce the risk of hospitalization for worsening heart failure.

How does CORABRAD 5MG Tablet work?

CORABRAD 5MG Tablet works by selectively inhibiting the "funny current" (I_f) in the sinoatrial (SA) node of the heart, which is the heart's natural pacemaker. This action reduces the heart rate, allowing the heart to pump blood more efficiently and decreasing its workload and oxygen demand. It achieves this without affecting blood pressure or the heart's contractility.

What is the usual dosage of CORABRAD 5MG Tablet?

For adults, the usual starting dose is 5 mg taken twice daily with food. Your doctor may adjust the dose after two weeks to achieve a resting heart rate between 50 and 60 beats per minute. The maximum recommended dose is 7.5 mg twice daily. In patients with certain heart rhythm problems or a history of slow heart rate, the initial dose might be lower, such as 2.5 mg twice daily.

What are the possible side effects of CORABRAD 5MG Tablet?

Common side effects include a slow heartbeat (bradycardia), temporary visual disturbances such as seeing bright spots or halos (luminous phenomena or phosphenes), increased blood pressure, headache, dizziness, fatigue, and an irregular heartbeat (atrial fibrillation). More serious side effects, though less common, can include a very slow heartbeat, worsening shortness of breath, chest pain, or fainting. If you experience severe symptoms, contact your doctor immediately.

Is CORABRAD 5MG Tablet safe during pregnancy or breastfeeding?

Pregnancy: CORABRAD 5MG Tablet is not recommended during pregnancy as it may harm an unborn baby. Females who are able to become pregnant must use effective contraception during treatment. If you become pregnant, stop taking the medication immediately and contact your healthcare provider. Breastfeeding: Breastfeeding is not recommended while taking CORABRAD 5MG Tablet. It is unknown if the medication passes into human breast milk, but animal studies indicate its presence in milk, posing a potential risk to breastfed infants.

Can CORABRAD 5MG Tablet be taken with other medications?

CORABRAD 5MG Tablet should not be taken with certain medications, including strong CYP3A4 inhibitors like some antifungals (e.g., ketoconazole, itraconazole), certain antibiotics (e.g., clarithromycin), some HIV medications (e.g., nelfinavir, ritonavir), certain antidepressants (e.g., nefazodone), and calcium channel blockers (e.g., diltiazem, verapamil). Concomitant use with other drugs that slow the heart rate (e.g., beta-blockers, digoxin, amiodarone) should be done with caution and under close medical supervision due to an increased risk of bradycardia. You should also avoid grapefruit juice and St. John's Wort while taking this medicine.

What precautions should be taken while using CORABRAD 5MG Tablet?

Before starting CORABRAD 5MG Tablet, inform your doctor if you have heart rhythm disorders, very low blood pressure, severe liver problems, recently worsened heart failure, or a resting heart rate below 70 beats per minute. Due to potential temporary vision changes, exercise caution when driving or operating machinery, especially at night or in situations with sudden changes in light intensity. Women of childbearing potential must use effective birth control.

What happens if a dose of CORABRAD 5MG Tablet is missed?

If you miss a dose of CORABRAD 5MG Tablet, skip the missed dose and take the next dose at your regularly scheduled time. Do not take a double dose to make up for a missed one.

How should CORABRAD 5MG Tablet be stored?

CORABRAD 5MG Tablet should be stored at room temperature, typically between 20°C to 25°C (68°F to 77°F), away from heat, moisture, and direct light. Keep the medication out of the reach of children.