Doran-o Tab

DORAN-O TAB by BESTOCHEM FORMULATIONS

DORAN-O TAB is a combination medication primarily used to address nausea, vomiting, and various gastrointestinal issues by reducing stomach acid production.

• Name:

  • Brand Name: Doran-O Tablet
  • Manufacturer: Bestochem Formulations (I) Ltd.

• Composition: DORAN-O TAB contains two active ingredients:

  • Ondansetron (4 mg)
  • Omeprazole (10 mg)

• Uses: DORAN-O TAB is prescribed for the treatment and prevention of:

  • Nausea and vomiting, especially those occurring after cancer chemotherapy, radiation treatment, or surgery.
  • Gastroesophageal reflux disease (GERD).
  • Ulcers in the stomach or intestine (peptic ulcers and acid-related disorders).
  • Symptoms like heartburn, indigestion, stomach pain, and irritation.
  • Pathological hypersecretory conditions, including Zollinger-Ellison syndrome.

• Dosage and Administration:

  • Take DORAN-O TAB as prescribed by your doctor.
  • It is typically taken without food, preferably one hour before a meal, usually once daily in the morning.
  • Swallow the tablet whole with a glass of water; do not chew, crush, or break it.
  • The dose and duration depend on your medical condition and response to treatment.
  • For chemotherapy-induced nausea/vomiting, the first dose may be given 30 minutes before treatment.

• Side Effects: Common side effects may include:

  • Headache
  • Constipation
  • Diarrhea
  • Flatulence (wind)
  • Stomach pain
  • Fatigue/tiredness
  • A feeling of warmth or flushing of the skin Most of these side effects are temporary and usually resolve over time. Serious side effects may include sudden blindness (2-3 minutes duration) in overdose cases, severe constipation, or muscle stiffness/spasms. Consult your doctor if side effects worsen or persist.

• Precautions:

  • Allergies: Inform your doctor if you are allergic to omeprazole, ondansetron, or similar medicines.
  • Pregnancy and Breastfeeding: Not recommended for use in pregnant women without consulting a doctor, and caution is advised for breastfeeding mothers.
  • Alcohol: Caution is advised when consuming alcohol with this medicine, as it may cause unwanted side effects.
  • Driving: May cause dizziness and visual disturbances; avoid driving or operating machinery if affected.
  • Liver and Kidney Conditions: Use with caution in patients with severe liver disease, as a lower dose may be recommended. Generally safe for patients with kidney disease.
  • Heart Conditions: Use cautiously in heart patients due to the risk of rhythm changes (QT prolongation).
  • Drug Interactions: Do not take with nelfinavir (for HIV infection) or apomorphine (for Parkinson's disease). Inform your healthcare team about all other medications you are taking to avoid potential interactions.
  • Other Warnings: Long-term use of omeprazole may increase the risk of osteoporosis-related fractures. Omeprazole may also alter results of some cancer-related tests.

• Storage:

  • Store in a cool and dry place, away from direct sunlight.
  • Keep out of sight and reach of children.
  • Maintain temperature ideally between 10ºC to 25ºC or below 30ºC.

Doran-O Tab is a medicine manufactured by BESTOCHEM FORMULATIONS that combines Omeprazole and Ondansetron. It is primarily used to address issues related to nausea, vomiting, and certain gastrointestinal conditions.

Here are some frequently asked questions about Doran-O Tab:

What is Doran-O Tab used for?

Doran-O Tab is used to treat and prevent nausea and vomiting, especially those occurring after cancer chemotherapy, radiation treatment, or surgery. It is also indicated for conditions such as gastroesophageal reflux disease (GERD), ulcers in the stomach or intestine, and to relieve symptoms of acid reflux, indigestion, and heartburn.

How does Doran-O Tab work?

Doran-O Tab contains two active ingredients: Omeprazole and Ondansetron. Omeprazole is a proton pump inhibitor that works by reducing the amount of acid produced in the stomach. Ondansetron is an anti-emetic that prevents nausea and vomiting by blocking the action of serotonin, a chemical messenger that stimulates the vomiting center in the brain.

What is the usual dosage for Doran-O Tab?

Doran-O Tab should be taken as prescribed by your doctor, who will determine the frequency and duration based on your medical condition. It is generally advised to take Doran-O Tab on an empty stomach, preferably one hour before a meal, usually once daily in the morning. The tablet should be swallowed whole with water and not crushed, chewed, or broken.

What are the possible side effects of Doran-O Tab?

Common side effects may include headache, diarrhea, constipation, flatulence (gas), stomach pain, fatigue, and a feeling of warmth or flushing of the skin. Most of these side effects are temporary and usually resolve as your body adjusts to the medicine. If side effects persist or worsen, consult your doctor. More serious side effects, though less common, can include dizziness, visual disturbances, chest pain, skin rashes, low blood pressure, increased serum creatinine, swollen lips, and heart rhythm changes.

Is Doran-O Tab safe during pregnancy or breastfeeding?

Pregnancy: Caution is advised when considering Doran-O Tab during pregnancy. While limited human studies exist, animal studies have shown potential harmful effects on the developing baby. It is crucial to consult your doctor to discuss the potential risks and benefits before taking this medicine if you are pregnant or planning a pregnancy. Breastfeeding: Doran-O Tab should be used with caution during breastfeeding. It is recommended to consult your doctor to understand any potential risks and benefits to the infant. Some information suggests minimal risk to the infant, but professional medical advice is essential.

Can Doran-O Tab be taken with other medications?

It is very important to inform your doctor about all other medications you are currently taking, including over-the-counter drugs and herbal supplements, as some may interact with Doran-O Tab. Doran-O Tab should generally not be taken with nelfinavir (for HIV infection) or apomorphine (for Parkinson's disease). Critical interactions have also been noted with ziprasidone and erlotinib. Additionally, caution is advised with medicines that can prolong the QT interval (a measure of heart's electrical activity), such as certain antipsychotics and arrhythmia drugs.

What precautions should be taken while using Doran-O Tab?

Inform your doctor if you have any allergies to omeprazole, ondansetron, or similar medications. Also, disclose any history of problems with sodium, magnesium, or potassium levels in your blood. If you have severe liver problems, a lower dose may be recommended, so inform your doctor. Heart patients should use Doran-O Tab with caution due to the risk of rhythm changes like QT prolongation. If you experience dizziness or visual disturbances, avoid driving or operating machinery. Alcohol consumption should be discussed with your doctor, as caution is advised.

What happens if a dose of Doran-O Tab is missed?

If you miss a dose of Doran-O Tab, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose or extra doses to make up for the missed one. Always consult your doctor for clarification.

How should Doran-O Tab be stored?

Doran-O Tab should be stored in a cool and dry place, away from direct sunlight. It is important to keep the medicine out of the sight and reach of children and pets. The recommended storage temperature is typically between 10ºC to 25ºC or below 30ºC (room temperature).