Empasov M 12.5/500mg Tab

EMPASOV M 12.5/500MG Tablet is a combination medicine containing Empagliflozin (12.5 mg) and Metformin (500 mg). It is primarily used to manage type 2 diabetes mellitus.

What is EMPASOV M 12.5/500MG Tablet used for?

EMPASOV M 12.5/500MG Tablet is used in adults with type 2 diabetes mellitus, along with diet and exercise, to improve blood sugar control. It also helps to reduce the risk of cardiovascular death in adults with type 2 diabetes and established cardiovascular disease, and to lower the risk of cardiovascular death and hospitalization in adults with heart failure. Additionally, it helps to reduce the risk of worsening kidney disease, end-stage kidney disease, cardiovascular death, and hospitalization in adults with chronic kidney disease.

How does EMPASOV M 12.5/500MG Tablet work?

This medicine combines two active ingredients: Empagliflozin and Metformin. Empagliflozin works by blocking the sodium-glucose co-transporter 2 (SGLT2) in the kidneys, which leads to increased removal of glucose from the body through urine, thereby lowering blood sugar levels. Metformin reduces the absorption of sugar from the stomach, decreases the release of stored sugar from the liver, and helps your body use insulin more effectively to lower blood sugar.

What is the usual dosage for EMPASOV M 12.5/500MG Tablet?

EMPASOV M 12.5/500MG Tablet contains 12.5 mg of Empagliflozin and 500 mg of Metformin. The exact dosage and frequency should be determined by your doctor. Typically, immediate-release tablets are taken twice daily with meals. Your doctor may start with a lower dose and gradually increase it to reduce gastrointestinal side effects. The maximum daily dose is generally not more than 25 mg of empagliflozin and 2000 mg of metformin. Tablets should be swallowed whole with water and not chewed, crushed, or split.

What are the possible side effects of EMPASOV M 12.5/500MG Tablet?

Common side effects can include urinary tract infections, genital yeast infections (in both men and women), increased urination, diarrhea, nausea, vomiting, abdominal discomfort, gas, headache, and feeling tired or weak. More serious but less common side effects include lactic acidosis (a serious build-up of lactic acid in the blood), diabetic ketoacidosis, dehydration, low blood pressure, severe allergic reactions, kidney problems, and a rare increased risk of lower limb amputations. Low blood sugar (hypoglycemia) can also occur, especially when taken with other diabetes medications like insulin or sulfonylureas.

Is EMPASOV M 12.5/500MG Tablet safe during pregnancy or breastfeeding?

Pregnancy: This medicine is generally not recommended during pregnancy, especially during the second and third trimesters, due to potential risks to the baby's developing kidneys observed in animal studies. It is important to discuss your treatment options with your doctor if you are pregnant or planning to become pregnant, as uncontrolled diabetes also carries significant risks.

Breastfeeding: It is typically not recommended while breastfeeding. While Empagliflozin is unlikely to pass into breast milk in significant amounts, there's a theoretical risk to the infant's developing kidney. Metformin is generally considered safe in small amounts in breast milk, but an alternative may be preferred, particularly for newborns or premature infants.

Can EMPASOV M 12.5/500MG Tablet be taken with other medications?

Yes, but it's important to inform your doctor about all other medications, including over-the-counter drugs, vitamins, and herbal products, as interactions can occur. Taking EMPASOV M with insulin or sulfonylureas can increase the risk of low blood sugar. Diuretics may also increase the risk of dehydration and low blood pressure. Certain medications, like carbonic anhydrase inhibitors or those affecting kidney function, can increase the risk of lactic acidosis when taken with Metformin. Your doctor may also advise you to temporarily stop this medicine before or during certain medical procedures, such as imaging with iodinated contrast dyes.

What precautions should be taken while on EMPASOV M 12.5/500MG Tablet?

Several precautions are important:

• Your doctor will monitor your kidney function before starting and periodically during treatment.
• Avoid excessive alcohol intake, as it can increase the risk of lactic acidosis.
• Stay well-hydrated to prevent dehydration, especially during illness or in hot weather.
• Be aware of the symptoms of low blood sugar, lactic acidosis, and diabetic ketoacidosis, and seek medical help if they occur.
• Inform your healthcare providers about all planned surgeries or diagnostic tests, as this medicine may need to be temporarily discontinued.
• Use with caution in elderly patients and those with pre-existing kidney, liver, or heart problems.

What happens if a dose of EMPASOV M 12.5/500MG Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should EMPASOV M 12.5/500MG Tablet be stored?

Store EMPASOV M 12.5/500MG Tablet in its original container at room temperature, away from excessive heat, moisture, and direct light. Keep it out of reach of children. Do not use any medicine that is outdated.