Xidorin 5mg Tab

XIDORIN 5MG TAB

Name

• Common Name: Xidorin 5MG TAB
• Brand Name: Xidorin Tablet
• Manufacturer: Sun Pharmaceutical Industries Ltd.

Composition

• Active Ingredient: Midodrine hydrochloride 5 mg

Uses

Xidorin 5MG TAB is an antihypotensive medication primarily used to treat low blood pressure (hypotension). It is particularly effective for symptomatic orthostatic hypotension, a condition characterized by a sudden drop in blood pressure upon standing, leading to symptoms such as dizziness, fainting, blurred vision, weakness, and fatigue. This medication helps to restore blood pressure stability and may also be prescribed for conditions like postural orthostatic tachycardia syndrome (POTS) or autonomic dysfunction.

Dosage and Administration

Xidorin 5MG TAB is for oral use and should be taken as prescribed by a physician.

• Typical Dosage: Usually 5-10 mg, taken two to three times daily during daytime hours. Doses should be administered at least 3 hours apart.
• Administration: Can be taken with or without food. It is recommended to take the medication when most active and standing, avoiding intake before prolonged periods of lying down. The last daily dose should be taken before an evening meal and at least 4 hours before bedtime to reduce the risk of supine hypertension at night.
• Swallow the tablet whole with water; do not chew, crush, or break it. Regular blood pressure monitoring is crucial during treatment.

Side Effects

While some side effects may resolve over time, consult a doctor if they persist or worsen.

• Common Side Effects: Headache, nausea, rash, urinary retention, difficulty in urination, flushing (sense of warmth), tingling of the scalp, chills, goosebumps, heartburn, stomach pain, dry mouth, dizziness, drowsiness, and trouble sleeping.
• Serious Side Effects: Supine hypertension (increased blood pressure while lying down), reflex bradycardia (slowed heart rate), arrhythmias, chest pain, palpitations, pounding in the ears, blurred vision, and in rare cases, stroke.

Precautions

• Contraindications: Do not use if allergic to midodrine, or in patients with severe heart disease (including slow pulse, heart attack, heart failure, arrhythmias, widening of the aorta), severe kidney disease, urinary retention, high blood pressure (especially supine hypertension), overactive thyroid (hyperthyroidism), pheochromocytoma (adrenal gland tumor), or narrow-angle glaucoma.
• Warnings: Use with caution in patients with liver impairment, a history of stroke, prostate disorders, or blood circulation problems.
• Pregnancy and Breastfeeding: Not recommended during pregnancy or breastfeeding.
• Pediatric Use: Not recommended for children below 18 years of age.
• Interactions: Inform your doctor about all medications you are taking, as Xidorin may interact with drugs that slow the heart rate (e.g., beta-blockers, digitalis). Alcohol consumption is not advisable as it may worsen dizziness.
• Activities: Avoid driving or operating heavy machinery if experiencing dizziness or lightheadedness.

Storage

Store in a cool and dry place below 30°C, away from direct sunlight. Keep out of the sight and reach of children. Protect from moisture and light.

XIDORIN 5MG TAB (Midodrine Hydrochloride) - Frequently Asked Questions

Xidorin 5MG TAB, manufactured by Sun Pharma, contains the active ingredient Midodrine hydrochloride. It is an antihypotensive medication primarily used to treat low blood pressure.

1. What is Xidorin 5MG TAB used for?

Xidorin 5MG TAB is primarily used to treat low blood pressure, also known as hypotension, especially orthostatic hypotension. This condition causes a sudden drop in blood pressure when moving from a sitting or lying position to standing, leading to symptoms like dizziness, fainting, blurred vision, and weakness. It is prescribed to patients whose daily routines are significantly affected by orthostatic hypotension and who haven't found adequate relief from other treatments.

2. How does Xidorin 5MG TAB work?

Xidorin 5MG TAB contains Midodrine hydrochloride, which works as an alpha-1 adrenergic receptor agonist. It acts on blood vessels via the sympathetic nervous system, causing them to constrict or tighten. This constriction increases blood pressure and improves blood flow, thereby correcting imbalances in blood distribution and relieving symptoms associated with low blood pressure.

3. What is the usual dosage for Xidorin 5MG TAB?

The usual starting dose for adults is typically 2.5 mg to 10 mg, taken two to three times a day during waking hours. Doses are usually taken 3 hours apart, with the last daily dose before an evening meal and at least 4 hours before bedtime to avoid supine hypertension (increased blood pressure while lying down). It can be taken with or without food. Always follow your doctor's specific instructions for dosage and duration.

4. What are the possible side effects of Xidorin 5MG TAB?

Common side effects of Xidorin 5MG TAB include headache, nausea, rash, urinary retention (difficulty in urination), flushing (sense of warmth), and goosebumps. It can also cause supine hypertension, which is an increase in blood pressure while lying down. Other possible side effects include skin tingling or itching, chills, stomach pain, dry mouth, dizziness, drowsiness, and trouble sleeping. If side effects persist or worsen, consult your doctor.

5. Is Xidorin 5MG TAB safe during pregnancy or breastfeeding?

Xidorin 5MG TAB is generally not recommended during pregnancy due to potential harmful effects on the developing baby. Limited human studies are available, but animal studies suggest caution. It is contraindicated in pregnancy. For breastfeeding mothers, information is limited, and its use is generally not recommended. It is best to consult your doctor to understand the potential risks and benefits if you are pregnant, planning to conceive, or breastfeeding.

6. Can Xidorin 5MG TAB be taken with other medications?

Yes, Xidorin 5MG TAB can interact with certain medications. You should inform your doctor about all medicines you are taking, including over-the-counter drugs and herbal products, as interactions may occur. Specific interactions include those with alpha blockers, beta blockers, certain psychiatric medicines, reserpine, guanethidine, antihistamines, thyroid hormones, tricyclic antidepressants, MAO-inhibitors, vasoconstrictors, and sympathomimetic agents. Combining Xidorin with alcohol can increase the risk of side effects like dizziness and lightheadedness.

7. What precautions should be taken while using Xidorin 5MG TAB?

Regularly monitor your blood pressure, especially while lying down, as the medication can cause supine hypertension. Inform your doctor if you have kidney or liver disease, severe heart disease, an enlarged prostate gland, urinary retention, pheochromocytoma, acute or severe kidney disease, overactive thyroid, or narrow-angle glaucoma, as it may be contraindicated or require caution. Avoid driving or operating heavy machinery if you experience dizziness or lightheadedness. Do not stop taking the medication suddenly without consulting your doctor.

8. What happens if a dose of Xidorin 5MG TAB is missed?

If you miss a dose of Xidorin 5MG TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

9. How should Xidorin 5MG TAB be stored?

Xidorin 5MG TAB should be stored in a cool and dry place, away from direct sunlight. Keep it at room temperature, typically between 10ºC to 30ºC, and out of the sight and reach of children.