Maxgalip At Tablet (10 Tab)

MAXGALIP AT TABLET

Maxgalip AT Tablet is a prescription medication manufactured by SUN PHARMA LABORATORIES LTD., primarily used for the management of various neuropathic pain conditions.

• Composition Each tablet contains Pregabalin (75 mg) and Amitriptyline (10 mg). Pregabalin works by modulating calcium channel activity in nerve cells to decrease pain, while Amitriptyline, a tricyclic antidepressant, increases levels of serotonin and noradrenaline to stop pain signal transmission in the brain.

• Uses Maxgalip AT Tablet is prescribed for neuropathic pain (nerve pain), including diabetic neuropathy, post-herpetic neuralgia, and fibromyalgia. It may also be used for migraine prevention, anxiety disorders, depression, and certain types of epileptic seizures.

• Dosage and Administration This medicine is taken orally, with or without food, as advised by your doctor. It is recommended to take it at a fixed time daily. Tablets should be swallowed whole and not crushed or chewed. Do not stop taking the medication suddenly; the dosage should be gradually tapered under medical supervision.

• Side Effects Common side effects include dizziness, drowsiness, dry mouth, constipation, blurred vision, weight gain, tiredness, nausea, vomiting, and headache. More serious, though rare, side effects can include severe allergic reactions, sudden vision changes, prolonged QT interval (affecting heart rhythm), or suicidal thoughts.

• Precautions Avoid alcohol consumption as it can increase drowsiness. Consult your doctor if you are pregnant or breastfeeding, as its use is generally not recommended. Inform your doctor about any pre-existing conditions such as heart problems, liver or kidney disease, glaucoma, diabetes, or mental health disorders like bipolar syndrome. This medicine may impair your ability to drive or operate machinery. Interactions can occur with other medications, including MAO inhibitors, blood thinners, and thyroid medications.

• Storage Store Maxgalip AT Tablet in its original packaging in a cool, dry place, away from direct heat and light, and out of reach of children and pets.

What is MAXGALIP AT TABLET used for?

MAXGALIP AT TABLET is primarily used for the management of neuropathic pain, which is pain caused by nerve damage or a malfunctioning nervous system. This includes conditions such as diabetic neuropathy, post-herpetic neuralgia (nerve pain after shingles), fibromyalgia, and other forms of peripheral neuropathic pain. It may also be used to manage certain anxiety disorders and depression.

How does MAXGALIP AT TABLET work?

MAXGALIP AT TABLET is a combination of two active ingredients: Pregabalin and Amitriptyline. Pregabalin, an anticonvulsant, works by binding to specific sites on voltage-gated calcium channels in the central nervous system. This action reduces the release of neurotransmitters involved in pain signaling, thereby calming damaged or overactive nerves. Amitriptyline is a tricyclic antidepressant that increases the levels of chemical messengers like serotonin and noradrenaline in the brain. These neurotransmitters help regulate mood and block the transmission of pain signals from the nerves to the brain. Together, they work to relieve nerve pain.

What is the usual dosage for MAXGALIP AT TABLET?

The dosage of MAXGALIP AT TABLET is determined by your doctor based on your specific medical condition, its severity, and your kidney function. It is usually taken orally with or without food, preferably at a fixed time each day to maintain consistent medicine levels in the blood. For neuropathic pain, an initial dose might be a single 75mg tablet taken once daily, often at bedtime. The doctor may gradually increase the dose, typically in increments of 75mg per day, every 3-7 days, until effective pain relief is achieved. The maximum daily dose should generally not exceed 600mg, divided into two or three doses. It is crucial to follow your doctor's instructions and not to adjust the dosage or stop the medication abruptly.

What are the possible side effects of MAXGALIP AT TABLET?

Common side effects of MAXGALIP AT TABLET include weight gain, dry mouth, blurred vision, dizziness, tiredness, sleepiness, drowsiness, nausea, vomiting, diarrhea, constipation, increased heart rate, and orthostatic hypotension (a sudden drop in blood pressure upon standing). Some individuals may also experience difficulty in urination or uncoordinated body movements. Less common but serious side effects can include changes in body temperature, difficulty breathing, palpitations, unusual mood or behavioral changes, and signs of frequent infections. MAXGALIP AT TABLET may also affect sexual desire or function and can temporarily change urine color to blue or green, which is usually harmless. If you experience persistent or severe side effects, or any unusual symptoms, you should consult your doctor.

Is MAXGALIP AT TABLET safe during pregnancy or breastfeeding?

MAXGALIP AT TABLET is generally not recommended for use during pregnancy unless your physician deems it absolutely necessary, as animal studies have shown potential harmful effects on the developing baby. For breastfeeding mothers, MAXGALIP AT TABLET is considered probably unsafe or not generally recommended, as its components may pass into breast milk and potentially harm the nursing infant. It is essential to consult your doctor to discuss the benefits and risks if you are pregnant, planning to become pregnant, or breastfeeding.

Can MAXGALIP AT TABLET be taken with other medications?

It is crucial to inform your doctor about all medications you are currently taking, including prescription drugs, over-the-counter medicines, and herbal supplements, to avoid potential drug interactions. MAXGALIP AT TABLET should not be taken with MAO inhibitors (a class of antidepressants like selegiline, isocarboxazid, or phenelzine). Caution is advised if you are taking medications for blood clots (e.g., warfarin), alcohol addiction (e.g., disulfiram), thyroid disorders (e.g., levothyroxine), high blood pressure (e.g., clonidine, benazepril), opioids, antihistamines, or anti-anxiety drugs. Additionally, it is advisable to avoid consuming grapefruit or grapefruit juice while on this medication, as it may interact with certain components of MAXGALIP AT.

What precautions should be taken while on MAXGALIP AT TABLET?

Due to potential side effects like drowsiness, dizziness, or blurred vision, you should avoid driving or operating heavy machinery until you understand how this medicine affects you. Alcohol consumption should be avoided or limited as it can increase these side effects. Do not stop taking MAXGALIP AT TABLET abruptly, as sudden discontinuation can lead to withdrawal symptoms such as anxiety, sleep difficulties, nausea, pain, and sweating; your doctor will guide you on a gradual tapering schedule. Exercise caution if you have a history of heart conditions, seizures, glaucoma, cardiovascular disease, urinary retention, liver disease, diabetes, or kidney problems. Monitoring for weight gain is also advisable, as the medicine can increase hunger; maintaining a balanced diet and regular exercise can help manage this. MAXGALIP AT TABLET is not recommended for children under 18 years of age.

What happens if a dose of MAXGALIP AT TABLET is missed?

If you miss a dose of MAXGALIP AT TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects. If you are unsure, consult your doctor or pharmacist.

How should MAXGALIP AT TABLET be stored?

MAXGALIP AT TABLET should be stored in its original packaging, tightly closed, in a cool, dry place, away from heat and direct light. It is important to keep this medication out of the reach and sight of children and to dispose of any unused medication responsibly to prevent accidental ingestion.