Dariten Od 7.5 Mg 10 Tablets

DARITEN OD 7.5 MG Extended-Release Tablets

DARITEN OD 7.5 MG is an extended-release medication used for the treatment of overactive bladder (OAB) symptoms. It is manufactured by SUN PHARMA LABORATORIES LTD.

• Name:

  • Brand Name: DARITEN OD 7.5 MG (also known as Enablex in some regions).
  • Common Name: Darifenacin extended-release tablets.

• Composition:

  • Active Ingredient: Each tablet contains 7.5 mg of Darifenacin. Darifenacin is a muscarinic antagonist, specifically a selective antagonist of the muscarinic (cholinergic) M3 subtype receptors.

• Uses: DARITEN OD 7.5 MG is primarily used to treat symptoms of an overactive bladder (OAB). These symptoms include:

  • Urge urinary incontinence (loss of bladder control due to a sudden, strong urge to urinate).
  • Urgency (a strong and immediate need to urinate).
  • Frequent urination (urinating more often than usual). It works by relaxing the muscles of the urinary bladder, which helps to increase its capacity to hold urine and reduce sudden contractions.

• Dosage and Administration:

  • Typical Dosage: The recommended starting dose for adults is 7.5 mg orally once a day.
  • Adjustment: The dose may be increased to 15 mg once daily based on individual patient response, typically after 2 weeks of starting therapy.
  • Administration: Tablets should be swallowed whole with water, with or without food. They should not be chewed, crushed, or divided. Do not stop taking the medicine without consulting a doctor.
  • Special Populations: For patients with moderate hepatic impairment, the daily dose should not exceed 7.5 mg. It is not recommended for patients with severe hepatic impairment.

• Side Effects:

  • Common Side Effects: Dry mouth, constipation, headache, dry eyes, nasal dryness, nausea, upset stomach (indigestion), and blurred vision.
  • Serious Side Effects: Though less common, serious side effects can include severe allergic reactions (angioedema, characterized by swelling of the face, lips, tongue, or throat), difficulty breathing, urinary retention (inability to empty the bladder), heat exhaustion/heat stroke (due to reduced sweating), and confusion or hallucinations.

• Precautions:

  • Contraindications: Do not use if allergic to darifenacin or if you have urinary retention, severe liver problems, uncontrolled narrow-angle glaucoma, or gastric retention.
  • Medical Conditions: Use with caution in patients with bladder blockage, intestinal or stomach problems (e.g., severe constipation, ulcerative colitis), myasthenia gravis, or moderate liver disease.
  • Activities: This medicine may cause dizziness, drowsiness, or blurred vision. Avoid driving or operating machinery until you know how it affects you.
  • Interactions: Inform your doctor about all other medications you are taking, including over-the-counter drugs, supplements, and herbal products, as darifenacin can interact with several medications (e.g., certain antifungals, antibiotics, HIV medications, antidepressants). Grapefruit juice may also interact with this medicine.
  • Pregnancy and Breastfeeding: Consult your doctor if pregnant or breastfeeding.

• Storage:

  • Store in a closed container at room temperature, away from heat, moisture, and direct light.
  • Generally, store below 30°C, or between 20°C to 25°C.
  • Keep out of reach of children and pets.

DARITEN OD 7.5 MG 10 TABLETS contains Darifenacin, an antimuscarinic medication used to treat symptoms of overactive bladder. Here are some frequently asked questions about this medicine:

What is DARITEN OD 7.5 MG used for?

DARITEN OD 7.5 MG is used to treat symptoms of an overactive bladder (OAB) in adults. This includes a sudden and frequent urge to urinate, inability to control urination (urge urinary incontinence), and urinating more often than usual (urinary frequency).

How does DARITEN OD 7.5 MG work?

This medicine works by relaxing the muscles of the urinary bladder. It does this by blocking M3 muscarinic acetylcholine receptors, which are primarily responsible for bladder muscle contractions. This action helps the bladder to retain a larger amount of urine and reduces the urgency to urinate.

What is the usual dosage for DARITEN OD 7.5 MG?

The recommended starting dose for adults is typically 7.5 mg once daily. Depending on your individual response and tolerability, your doctor may increase the dose to 15 mg once daily after two weeks. It can be taken with or without food.

What are the possible side effects of DARITEN OD 7.5 MG?

Common side effects may include dry mouth, constipation, headache, nausea, indigestion, and blurred vision. Less common side effects can include dizziness, urinary tract infection (UTI), and nasal dryness. Most side effects are temporary and resolve with time. If they persist or worsen, consult your doctor.

Is DARITEN OD 7.5 MG safe during pregnancy or breastfeeding?

DARITEN OD 7.5 MG is generally not recommended during pregnancy unless absolutely necessary, and only if the potential benefit outweighs the risk to the fetus. For breastfeeding mothers, caution should be exercised as it is not known whether darifenacin passes into breast milk. It is advisable to consult your doctor before taking this medicine if you are pregnant or breastfeeding.

Can DARITEN OD 7.5 MG be taken with other medications?

Taking DARITEN OD 7.5 MG with certain other medications can lead to interactions. For example, its dosage may need to be adjusted if taken with strong CYP3A4 inhibitors like ketoconazole, itraconazole, ritonavir, nelfinavir, clarithromycin, or nefazodone. Concomitant use with other anticholinergic agents may increase side effects such as dry mouth, constipation, and blurred vision. Always inform your doctor about all medicines, supplements, and herbal products you are taking.

What precautions should be taken while using DARITEN OD 7.5 MG?

DARITEN OD 7.5 MG should be used with caution if you have conditions such as clinically significant bladder outflow obstruction (risk of urinary retention), gastrointestinal obstructive disorders (risk of gastric retention), or uncontrolled narrow-angle glaucoma. This medication may cause dizziness or blurred vision, so avoid driving or operating machinery until you know how it affects you. Alcohol consumption should be avoided as it may increase symptoms of an overactive bladder and can worsen side effects like dizziness or sleepiness.

What happens if a dose of DARITEN OD 7.5 MG is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should DARITEN OD 7.5 MG be stored?

DARITEN OD 7.5 MG tablets should be stored at room temperature, ideally between 15°C to 30°C (59°F to 86°F), in a cool, dry place, and protected from light and moisture. Keep the medicine out of the reach of children and pets.