Sitared M Xr 100/500

SITARED M XR 100/500

SITARED M XR 100/500 is a combination medication manufactured by SUN PHARMACEUTICAL INDUSTRIES LTD, designed for the management of Type 2 Diabetes Mellitus.

• Composition:

  • Active Ingredients: Each tablet contains Sitagliptin 100 mg and Metformin Hydrochloride 500 mg. Metformin is in an extended-release (XR) formulation.

• Uses: SITARED M XR 100/500 is prescribed to control high blood sugar levels in adults with Type 2 Diabetes Mellitus, particularly when diet and exercise alone are insufficient or when monotherapy with either sitagliptin or metformin is inadequate. It helps improve glycemic control, enhance insulin sensitivity, and prevent diabetes-related complications such as kidney damage, eye damage, nerve problems, and cardiovascular issues. It may also be used off-label for Polycystic Ovary Syndrome (PCOS).

• Dosage and Administration: The usual dose is one tablet, once or twice daily, as prescribed by your doctor. It is important to take this medication with food to help prevent stomach upset. Tablets should be swallowed whole with a glass of water and not crushed, chewed, or broken. Do not stop taking the medicine without consulting your doctor.

• Side Effects:

  • Common: Low blood sugar (hypoglycemia), nausea, vomiting, diarrhea, stomach pain, headache, upper respiratory tract infection, metallic taste, constipation, flatulence, sore throat, and joint pain.
  • Serious (Rare): Lactic acidosis (characterized by vomiting, stomach pain, difficulty breathing, tiredness, muscle cramps), pancreatitis (inflammation of the pancreas), severe allergic reactions (e.g., anaphylaxis, angioedema, Stevens-Johnson syndrome), and liver problems.

• Precautions: Avoid if allergic to sitagliptin, metformin, or other ingredients. It is contraindicated in patients with severe kidney or liver disease, Type 1 Diabetes Mellitus, diabetic ketoacidosis, severe uncontrolled diabetes, alcoholism, shock, or breathing/circulation problems. Caution is advised in pregnancy and breastfeeding, and for elderly patients; consult a doctor. Alcohol consumption should be limited due to an increased risk of lactic acidosis. Regular monitoring of blood sugar levels and kidney function is necessary. Interactions with other anti-diabetic medications, especially insulin or sulfonylureas, can increase the risk of hypoglycemia.

• Storage: Store SITARED M XR 100/500 at a temperature not above 30°C in a cool and dry place. Keep it out of the reach of children and pets, and away from moisture and heat.

Here are the most frequently asked questions about SITARED M XR 100/500, along with their concise answers:

What is SITARED M XR 100/500 used for?

SITARED M XR 100/500 is a combination medication primarily used to manage high blood sugar levels in adults with Type 2 Diabetes Mellitus. It is prescribed in conjunction with a healthy diet and regular exercise to improve glycemic control and help prevent serious complications of diabetes, such as kidney damage, blindness, nerve problems, and cardiovascular issues.

How does SITARED M XR 100/500 work?

This medicine contains two active ingredients: Sitagliptin and Metformin. Sitagliptin, a DPP-4 inhibitor, works by increasing the body's production of insulin (especially after meals) and decreasing the amount of sugar produced by the liver. Metformin, a biguanide, reduces glucose production in the liver, delays glucose absorption from the intestines, and enhances the body's sensitivity to insulin. Together, they help control blood glucose levels from rising too high after meals.

What is the usual dosage for SITARED M XR 100/500?

The usual dose is typically one tablet, once or twice daily, as prescribed by your doctor. It is crucial to take this medication with food to help prevent stomach upset. The tablet should be swallowed whole with a glass of water and not crushed, chewed, or broken. Your doctor will determine the appropriate dose and duration of therapy based on your condition and blood sugar levels.

What are the possible side effects of SITARED M XR 100/500?

Common side effects can include hypoglycemia (low blood glucose levels), characterized by dizziness, sweating, hunger pangs, dry mouth, and skin. Other common side effects are changes in taste, nausea, diarrhea, stomach pain, headache, constipation, loss of appetite, and upper respiratory symptoms. A rare but serious side effect is lactic acidosis, which requires immediate medical attention.

Is SITARED M XR 100/500 safe during pregnancy or breastfeeding?

SITARED M XR 100/500 is generally not recommended for use during pregnancy or breastfeeding. Components of the tablet can potentially harm an unborn or breastfed baby. It is important to inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding, so they can advise on alternative treatments or assess the risks and benefits.

Can SITARED M XR 100/500 be taken with other medications?

SITARED M XR 100/500 can interact with certain other medications. Taking it with other anti-diabetic medicines, such as insulin or sulfonylureas, can significantly increase the risk of low blood sugar (hypoglycemia). It's important to inform your doctor about all medicines, supplements, or herbal products you are currently taking or plan to take to avoid potential interactions.

What precautions should be taken while using SITARED M XR 100/500?

Avoid taking this medicine if you have severe kidney or liver disease, Type 1 diabetes, diabetic ketoacidosis, severe infections, or dehydration. Inform your doctor if you have a history of pancreatitis, heart disease, or low vitamin B12 levels. Alcohol consumption should be avoided as it increases the risk of lactic acidosis. Regular monitoring of blood sugar levels and kidney function tests is recommended during treatment.

What happens if a dose of SITARED M XR 100/500 is missed?

If you miss a dose of SITARED M XR 100/500, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to compensate for a missed one.

How should SITARED M XR 100/500 be stored?

Store SITARED M XR 100/500 in a cool and dry place, away from direct sunlight and moisture. The ideal storage temperature is typically below 30°C (or between 10°C to 25°C). Keep the medication out of sight and reach of children and pets.