Dabigo 75 Mg Capsule (10 Cap)

DABIGO 75 MG CAPSULE

Name:

• Brand Name: DABIGO 75 MG CAPSULE
• Common Name: Dabigatran Etexilate

Composition: Each capsule contains 75 mg of Dabigatran Etexilate, which is the active ingredient.

Uses: DABIGO 75 MG CAPSULE is an anticoagulant, commonly referred to as a blood thinner, used to prevent and treat blood clots. It is prescribed for:

• Reducing the risk of stroke and systemic embolism in adult patients with non-valvular atrial fibrillation (irregular heartbeat).
• Treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE).
• Prevention of blood clots following hip or knee replacement surgeries.

Dosage and Administration: The dosage of DABIGO 75 MG CAPSULE varies based on the medical condition and individual patient factors. For adults, a common dosage is 150 mg taken orally twice daily, but a lower dose of 75 mg twice daily may be prescribed, especially for those at increased risk of bleeding, aged 75 years or older, or with kidney problems. The capsules should be swallowed whole with a glass of water, with or without food. Do not crush, chew, or open the capsules, as this may increase the risk of side effects. It is crucial to take the medicine at the same time each day and not to stop or alter the dosage without consulting a doctor, as abrupt discontinuation can increase the risk of blood clots, stroke, or heart attack.

Side Effects:

• Common Side Effects: Stomach upset, nausea, indigestion, diarrhea, abdominal pain, and an increased tendency to bleed (e.g., nosebleeds, bruising).
• Serious Side Effects: Severe bleeding (manifesting as bloody/black stools, vomiting blood, red/dark brown urine, unusual bruising), severe headache, seizures, allergic reactions (skin rash, itching, swelling), changes in vision, and fatigue. Immediate medical attention is required for serious symptoms.

Precautions: DABIGO 75 MG CAPSULE is not suitable for everyone. Avoid taking this medicine if you have severe kidney or liver problems, active bleeding, or are currently taking other medications that reduce blood clotting. Caution is advised if you have a history of bleeding disorders, recent injury, or are undergoing surgery/dental work (temporary discontinuation may be necessary). Alcohol consumption should be avoided as it can increase the risk of bleeding. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Regular monitoring of kidney function may be necessary. Interactions can occur with certain medications, including verapamil, amiodarone, quinidine, clarithromycin, posaconazole, rifampicin, carbamazepine, phenytoin, and NSAIDs; always inform your doctor about all medications you are taking.

Storage: Store DABIGO 75 MG CAPSULE in its original package to protect from moisture, at room temperature (between 15°C to 30°C or 59°F to 86°F). Keep the bottle tightly closed and out of the reach of children. Once the bottle is opened, the medicine should be used within 4 months.

DABIGO 75 MG CAPSULE, containing the active ingredient dabigatran etexilate, is an anticoagulant medication commonly referred to as a blood thinner. It is used to prevent and treat various blood clot-related conditions.

Here are some frequently asked questions about DABIGO 75 MG CAPSULE:

What is DABIGO 75 MG CAPSULE used for?

DABIGO 75 MG CAPSULE is primarily used to prevent and treat blood clots in different parts of the body. It helps reduce the risk of stroke and systemic embolism in adults with non-valvular atrial fibrillation (an irregular heart rhythm). It is also prescribed for the treatment and prevention of deep vein thrombosis (DVT, blood clots in the legs) and pulmonary embolism (PE, blood clots in the lungs), and to prevent blood clots after hip or knee replacement surgeries.

How does DABIGO 75 MG CAPSULE work?

DABIGO 75 MG CAPSULE is a direct thrombin inhibitor. Its active ingredient, dabigatran, works by directly and reversibly blocking thrombin, an enzyme crucial for blood clot formation. By inhibiting thrombin, it prevents fibrinogen from converting into fibrin, which is an essential step in the clotting cascade, thereby allowing blood to flow more freely.

What is the usual dosage for DABIGO 75 MG CAPSULE?

The dosage of dabigatran etexilate can vary depending on the condition being treated and individual patient factors, such as kidney function. For stroke prevention in patients with non-valvular atrial fibrillation, a common adult dose is 150 mg twice daily, but a 75 mg twice daily dose is often prescribed for patients with moderate kidney impairment (creatinine clearance 15-30 mL/min) or those who are 80 years or older. It should be taken as prescribed by your doctor, with or without food, and swallowed whole with water. It is generally recommended to take it at the same time each day.

What are the possible side effects of DABIGO 75 MG CAPSULE?

The most common side effects are related to bleeding, such as easy bruising, nosebleeds, bleeding gums, or prolonged bleeding from cuts. Gastrointestinal issues like stomach upset, indigestion, nausea, diarrhea, and stomach pain are also frequently reported. More serious, though less common, side effects can include severe internal bleeding, anemia, headaches, allergic reactions (rash, itching, swelling, difficulty breathing), and fatigue. If you experience any severe or persistent side effects, contact your doctor immediately.

Is DABIGO 75 MG CAPSULE safe during pregnancy or breastfeeding?

DABIGO 75 MG CAPSULE is generally not recommended during pregnancy unless specifically advised by a doctor who has weighed the potential benefits against the risks. Women of childbearing age should take precautions to avoid pregnancy while on this medication. It is also advised not to breastfeed while taking DABIGO 75 MG CAPSULE, as there is limited information on its transfer into breast milk and potential risks to the infant.

Can DABIGO 75 MG CAPSULE be taken with other medications?

DABIGO 75 MG CAPSULE can interact with several other medications, which may increase the risk of bleeding. It's crucial to inform your doctor about all prescription, over-the-counter, herbal, and supplement medications you are taking. Medications to avoid or use with caution include other anticoagulants (e.g., warfarin, heparin), antiplatelet agents (e.g., aspirin, clopidogrel), and NSAIDs (e.g., ibuprofen). Certain antifungals (like ketoconazole), antivirals, cyclosporine, dronedarone, verapamil, amiodarone, quinidine, and clarithromycin can increase dabigatran levels, while some anticonvulsants (like carbamazepine, phenytoin) and rifampicin can decrease its effectiveness. Alcohol consumption can also increase the risk of bleeding.

What precautions should be taken while taking DABIGO 75 MG CAPSULE?

Due to the increased risk of bleeding, be cautious with activities that may cause injury. Inform your doctor if you have a history of bleeding disorders, ulcers, recent surgery, or impaired kidney or liver function, as this medicine may not be suitable for you or may require dose adjustments. Do not stop taking DABIGO 75 MG CAPSULE or alter your dose without consulting your doctor, as this can significantly increase your risk of blood clot formation. Unlike some other anticoagulants, routine blood tests like PT-INR are generally not required while on this medication.

What happens if a dose of DABIGO 75 MG CAPSULE is missed?

If you miss a dose of DABIGO 75 MG CAPSULE, take it as soon as you remember. However, if it is almost time for your next scheduled dose (typically less than 6 hours away), skip the missed dose and continue with your regular dosing schedule. Never take a double dose to compensate for a missed one, as this can increase the risk of bleeding. Missing doses can increase the risk of blood clot formation.

How should DABIGO 75 MG CAPSULE be stored?

DABIGO 75 MG CAPSULE should be stored in its original packaging to protect it from moisture. Keep it at room temperature, generally between 15°C to 30°C (59°F to 86°F), and out of reach of children and pets. The bottle should be tightly closed after each use. Once the bottle is opened, the medicine should typically be used within 4 months (or 60 days, depending on specific product instructions) and discarded safely if unused beyond that period.