Dapaturnm Forte 10

Here is a detailed product description for Dapaturn M Forte 10 by Lupin Ltd.:

Dapaturn M Forte 10 Tablet

Name

• Common Name: Dapaturn M Forte 10 Tablet, Dapaturn M Forte 10 Tablet ER
• Brand Name: Dapaturn M Forte 10
• Manufacturer: Lupin Ltd.

Composition

Dapaturn M Forte 10 Tablet is a fixed-dose combination medication containing two active ingredients:

• Dapagliflozin: 10 mg
• Metformin: 1000 mg

Uses

Dapaturn M Forte 10 Tablet is primarily used in adults for the management of Type 2 diabetes mellitus, often as an adjunct to diet and exercise. It helps control high blood glucose levels by improving insulin sensitivity, decreasing glucose production in the liver, and promoting glucose excretion through urine.

Specific benefits and uses include:

• Treatment of Type 2 diabetes mellitus.
• Improvement of glycemic control.
• Reduction of the risk of serious complications associated with diabetes, such as kidney damage, heart disease, stroke, blindness, and nerve damage.
• May contribute to weight loss or prevent weight gain due to its action on glucose metabolism.
• Reduces the risk of heart failure in patients with Type 2 diabetes and heart disease.

Dosage and Administration

This medication should be taken orally as directed by a healthcare professional, usually once daily in the morning.

• It is often advised to take Dapaturn M Forte 10 Tablet with a meal to reduce the chance of side effects.
• Swallow the tablet whole with water; do not crush, chew, or break it.
• Take it at the same time each day to help remember.
• Do not stop taking Dapaturn M Forte 10 Tablet without consulting your doctor, as this could lead to increased blood sugar levels and a higher risk of complications.

Side Effects

While generally well-tolerated, Dapaturn M Forte 10 Tablet may cause some side effects:

• Common Side Effects: Frequent urination, mild skin rash or itchy skin, diarrhea, stomach ache, loss of appetite, nausea, vomiting, headache, dizziness, low blood sugar (hypoglycemia) (especially when taken with other diabetic medications or alcohol, or if meals are delayed/missed), sore throat, nasal congestion, runny nose, urinary tract infection, genital fungal infection, back pain, increased hematocrit, decreased creatinine clearance, dyslipidemia, taste changes, difficulty in urination, tremors, discomfort when passing urine, changes in cholesterol/fat levels, increased red blood cells, and flatulence.
• Serious Side Effects (rare but require immediate medical attention): Severe dehydration, excessive thirst, kidney problems (reduced urine output, swelling in legs or ankles), lactic acidosis (muscle pain, breathing difficulty, weakness), or diabetic ketoacidosis.

Precautions

• Contraindications: Do not take if you have Type 1 diabetes mellitus, severe kidney or liver disease, a recent heart attack, heart failure, septicemia, severe infection, diabetic ketoacidosis, hypoxemia, or uncontrolled diabetes. Also contraindicated in cases of severe hypersensitivity to dapagliflozin or metformin.
• Pregnancy and Breastfeeding: Generally not recommended during pregnancy (especially the second and third trimesters) or breastfeeding. Consult your doctor to discuss risks and benefits.
• Alcohol: Avoid excessive alcohol consumption as it can increase the risk of lactic acidosis and low blood sugar (hypoglycemia).
• Elderly Patients: Not recommended for individuals aged 85 years or older. Caution is advised for other elderly patients, and dose adjustments or special monitoring may be required.
• Allergies: Inform your doctor about any known allergies to the components of Dapaturn M Forte 10 Tablet.
• Pre-existing Conditions: Inform your doctor if you have a history of heart, kidney, or liver disease; breathing problems; blood disorders; dehydration; low blood pressure; yeast infection of the genitals; urinary tract infection; or if you are on diuretics.
• Monitoring: Regular monitoring of blood sugar levels and kidney function is essential during treatment.
• Driving: Your ability to drive or operate machinery may be affected if your blood sugar levels are too high or too low.

Storage

Store Dapaturn M Forte 10 Tablet in a cool and dry place, away from direct sunlight. The typical storage temperature is between 10ºC to 25ºC or below 30ºC. Keep it out of sight and reach of children and pets.

DAPATURNM FORTE 10, manufactured by LUPIN LTD., is a combination medication used to manage Type 2 Diabetes Mellitus. It contains two active ingredients: Metformin (1000 mg) and Dapagliflozin (10 mg). This medication is prescribed alongside diet and exercise to help control blood sugar levels.

What is DAPATURNM FORTE 10 used for?

DAPATURNM FORTE 10 is primarily used for the treatment of Type 2 Diabetes Mellitus in adults. It helps improve glycemic control, assists in weight management, and may reduce cardiovascular risk factors. It can be used when diet, exercise, and other conventional medicines do not provide an adequate response.

How does DAPATURNM FORTE 10 work?

DAPATURNM FORTE 10 combines two medications with different mechanisms of action. Metformin, a biguanide, works by reducing glucose production in the liver and improving the body's sensitivity to insulin. Dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, helps lower blood sugar by blocking the reabsorption of glucose in the kidneys, leading to increased excretion of excess sugar through urine.

What is the usual dosage for DAPATURNM FORTE 10?

DAPATURNM FORTE 10 should be taken orally with meals, as prescribed by your doctor. It is important to follow the dosage regimen and instructions provided, swallowing the tablets whole with a glass of water without crushing or chewing them. The dose and duration will be decided by your doctor based on your age, body weight, and disease condition.

What are the possible side effects of DAPATURNM FORTE 10?

Common side effects include diarrhea, nausea, abdominal pain, urinary tract infections, and hypoglycemia (low blood sugar). Other possible side effects may include genital fungal infections, headache, vomiting, sore throat, nasal congestion, runny nose, skin rash, changes in taste, dizziness, and back pain. Most side effects are temporary and often resolve as your body adjusts to the medication.

Is DAPATURNM FORTE 10 safe during pregnancy or breastfeeding?

DAPATURNM FORTE 10 is generally not recommended during pregnancy, especially in the second and third trimesters, due to insufficient safety data and potential risks to the unborn baby. It is also not advised during breastfeeding, as dapagliflozin may pass into breast milk and affect the infant's kidney development. Always consult your doctor for suitable alternatives if you are pregnant or breastfeeding.

Can DAPATURNM FORTE 10 be taken with other medications?

There are potential drug interactions with certain medications. It is crucial to inform your doctor about all medicines you are taking, including over-the-counter drugs, herbal supplements, and other antidiabetic medications, as some can increase the risk of lactic acidosis or affect blood sugar levels.

What precautions should be taken while using DAPATURNM FORTE 10?

Precautions include avoiding excessive alcohol intake, as it may increase the risk of lactic acidosis. Patients with liver disease, moderate to severe kidney disease, or a history of severe allergic reactions to any of the ingredients should not use this medicine. Caution is advised for elderly patients, and dose adjustments or special monitoring may be required. Regular monitoring of blood sugar levels is important.

What happens if a dose of DAPATURNM FORTE 10 is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How should DAPATURNM FORTE 10 be stored?

DAPATURNM FORTE 10 should be stored at room temperature (20-25°C), protected from moisture and light. Keep it in a cool and dry place, and out of the reach of children.