Durabolin 25 Mg Inj

DURABOLIN 25 MG Injection by ZYDUS HEALTHCARE- FORTIZA DIV

• Name:

  • Common Name: Nandrolone Injection
  • Brand Name: DURABOLIN 25 MG Injection / Deca Durabolin 25 MG Injection

• Composition:

  • Active Ingredient: Nandrolone Decanoate 25 mg

• Uses:

  • Postmenopausal Osteoporosis: Used to treat and prevent bone loss, strengthening bones, and reducing fracture risk in women after menopause.
  • Anemia: Particularly effective in treating anemia associated with renal insufficiency by stimulating red blood cell production.
  • Muscle Wasting Conditions: Helps promote tissue growth and recovery in conditions involving severe muscle loss.
  • Breast Cancer: Used as supportive care in advanced breast cancer.

• Dosage and Administration:

  • DURABOLIN 25 MG Injection is administered by deep intramuscular injection by a healthcare professional. It should not be self-administered.
  • Dosage is determined by the doctor based on the patient's clinical condition.
  • For conditions like negative nitrogen balance or osteoporosis, a recommended dose can be 25-50 mg every week.

• Side Effects:

  • Common: Acne, edema (swelling of legs, ankles, feet), fluid retention, nausea, breast enlargement, increased libido, hoarseness, diarrhea, chills, trouble sleeping.
  • Serious (especially in women): Virilization (development of male sexual characteristics such as deepening of voice, increased hair growth, irregular menstruation), impaired liver function, increased blood calcium levels, liver tumors, and blood-filled cysts in the liver.

• Precautions:

  • Pregnancy and Breastfeeding: Contraindicated during pregnancy due to potential harm to the fetus and not advised for breastfeeding mothers.
  • Medical Conditions: Not recommended for people with severe kidney or liver problems, heart failure, prostate cancer, breast cancer with hypercalcemia, or porphyria.
  • Allergies: Should not be used if allergic to Nandrolone or any ingredients like Arachis oil (peanut oil).
  • Monitoring: Patients should be monitored for signs of virilization, fluid retention, and changes in blood tests (e.g., hemoglobin, lipids, liver function).
  • Children: Should not be administered to children and adolescents who have not attained puberty.
  • Misuse: Misuse by sportspersons is prohibited.

• Storage:

  • Store below 30°C, away from light and moisture.
  • Keep out of the reach of children.

Durabolin 25 mg Injection, manufactured by Zydus Healthcare - Fortiza Division, contains Nandrolone Decanoate, an anabolic steroid. It is primarily used to strengthen bones and promote tissue growth.

What is Durabolin 25 mg Injection used for?

Durabolin 25 mg Injection is primarily used to treat osteoporosis in post-menopausal women, a condition where bones become weak and brittle. It also helps manage anemia associated with renal insufficiency, certain types of breast cancer, and muscle wasting conditions by promoting tissue growth and protein production.

How does Durabolin 25 mg Injection work?

This medicine contains nandrolone, an anabolic steroid that mimics the effects of testosterone. It works by stimulating bone-forming cells (osteoblasts) and inhibiting bone-breaking cells (osteoclasts), which helps to strengthen bones, prevent bone loss, and improve bone density. It also promotes tissue growth, protein synthesis, and red blood cell production.

What is the usual dosage of Durabolin 25 mg Injection?

The dosage and frequency of Durabolin 25 mg Injection are determined by a doctor based on the individual's specific medical condition. It is typically administered as a deep intramuscular injection, often once every week or every two to three weeks. For osteoporosis, a recommended dose might be 50 mg every week.

What are the possible side effects?

Common side effects include injection site reactions, nausea, itching, acne, swelling of ankles or feet (oedema/fluid retention), and breast enlargement. In women, it may also cause masculinization symptoms such as hoarseness or changes in voice, increased facial or body hair growth (hirsutism), irregular menstruation, and increased libido (sexual desire). Other potential side effects include trouble sleeping, chills, impaired liver function, diarrhea, and increased blood calcium levels.

Is it safe during pregnancy or breastfeeding?

Durabolin 25 mg Injection is unsafe and must not be used during pregnancy due to limited safety information in human pregnancy and the risk of masculinization of the fetus. It is also not recommended for use during breastfeeding as it is unknown if nandrolone passes into human breast milk and may affect the baby.

Can it be taken with other medications?

Durabolin 25 mg Injection can interact with several medications. It may affect the way insulin or other anti-diabetic medications work, requiring close monitoring. Concomitant use with blood thinners like Warfarin or heparin may alter the effects of the injection. It should also be used with caution alongside ACTH or corticosteroids and erythropoietin. Inform your doctor about all medicines, supplements, or herbal preparations you are taking.

What precautions should be taken?

Inform your doctor if you have migraines, epilepsy, diabetes, high blood pressure, heart, liver, or kidney problems, or a history of breast cancer that has spread to the bones. This medicine may interfere with laboratory tests, so inform the laboratory personnel that you are using Durabolin Injection. Patients should be monitored for fluid retention, especially those with cardiac or renal dysfunction. Regular blood tests may be required to monitor hemoglobin levels, blood lipids, and liver function. If signs of virilization (development of male characteristics in females) occur, discontinuation of treatment should be considered.

What happens if a dose is missed?

As Durabolin 25 mg Injection is administered by a doctor or nurse, it is unlikely for a dose to be missed. If you believe a dose might have been missed, you should inform your doctor or nurse. Do not self-administer the injection.

How should it be stored?

Durabolin 25 mg Injection should be stored at room temperature, below 30°C, and protected from light and moisture. Keep it out of the reach of children.