Clopitorva 20 Mg Capsule (10 Cap)

CLOPITORVA 20 MG CAPSULE by ZYDUS HEALTHCARE LIMITED

Name

• Brand Name: CLOPITORVA 20 MG CAPSULE
• Common Name: Clopitorva 20 Capsule

Composition CLOPITORVA 20 MG CAPSULE contains two active ingredients:

• Atorvastatin (20 mg): A lipid-lowering medication that inhibits the enzyme HMG-CoA reductase, responsible for cholesterol production in the liver. It reduces "bad" cholesterol (LDL) and triglycerides while modestly increasing "good" cholesterol (HDL).
• Clopidogrel (75 mg): An antiplatelet agent (blood thinner) that prevents platelets from sticking together, thereby reducing the formation of blood clots in the arteries.

Uses This combination medicine is primarily prescribed for:

• Cardiovascular Disease Prevention: To reduce the risk of serious cardiovascular events such as heart attacks and strokes in individuals with or without a history of heart disease.
• Hyperlipidemia: To lower elevated levels of "bad" cholesterol (LDL) and triglycerides in the blood.
• Post-Cardiac Procedures: May be used after procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) to prevent blood clot formation within stents and grafts.

Dosage and Administration

• CLOPITORVA 20 MG CAPSULE is typically taken orally, once daily.
• It can be taken with or without food, though some sources suggest taking it with food to avoid stomach upset.
• Swallow the capsule whole with a glass of water; do not break, cut, or chew it.
• Take the medicine regularly at evenly spaced intervals, ideally at the same time each day, as directed by your doctor.
• The dose and duration of treatment will depend on the patient's condition and response to treatment. Do not exceed the prescribed dosage.

Side Effects

• Common Side Effects: Headache, dizziness, nausea, diarrhea, stomach pain, indigestion, fatigue, muscle pain or weakness, joint pain, nosebleeds, and ankle swelling (oedema).
• Serious Side Effects (Seek medical attention if experienced): Persistent or severe muscle pain, weakness, or cramps (especially if accompanied by fever), unusual bruising or bleeding, yellowing of the skin or eyes, severe abdominal pain, and symptoms of an allergic reaction (e.g., rash, itching, swelling).

Precautions

• Allergies: Do not take if you are allergic to atorvastatin, clopidogrel, or any other ingredients.
• Bleeding Risk: This medicine increases the risk of bleeding. Exercise caution during activities that may cause injury and inform your doctor before any surgical or dental procedures.
• Liver Disease: Not recommended for patients with active liver disease or abnormal liver function tests. Inform your doctor about any liver conditions.
• Pregnancy and Breastfeeding: CLOPITORVA 20 MG CAPSULE is contraindicated during pregnancy and breastfeeding.
• Alcohol: Avoid consuming alcohol, as it may increase the risk of liver damage and other side effects.
• Grapefruit Juice: Avoid grapefruit juice as it can interact with atorvastatin.
• Drug Interactions: Inform your doctor about all other medications you are taking, including NSAIDs, anti-diabetic drugs (like Metformin), anti-tubercular drugs (like Rifampin), amlodipine, and cyclosporine, as interactions can occur.
• Diabetes and Kidney Impairment: Use with caution in diabetic patients (monitor blood sugar) and those with renal impairment (regular renal function tests may be recommended).
• Children: Not recommended for use in children and adolescents below 18 years due to a lack of safety data.

Storage

• Store below 25°C or 30°C in a clean, dry place.
• Protect from moisture, direct sunlight, and heat.
• Keep out of the sight and reach of children and pets.

What is CLOPITORVA 20 MG CAPSULE used for?

CLOPITORVA 20 MG CAPSULE is a combination medicine primarily used to prevent serious cardiovascular events such as heart attacks and strokes. It works by lowering "bad" cholesterol (LDL) and triglyceride levels, while also increasing "good" cholesterol (HDL), and preventing the formation of harmful blood clots. It is also prescribed after cardiac procedures like stent placement to prevent clot formation.

How does CLOPITORVA 20 MG CAPSULE work?

This medicine contains two active ingredients: Atorvastatin (20 mg) and Clopidogrel (75 mg). Atorvastatin reduces cholesterol production in the liver by inhibiting the enzyme HMG-CoA reductase, thereby lowering LDL cholesterol. Clopidogrel is an antiplatelet agent that prevents blood platelets from clumping together and forming clots in the arteries.

What is the usual dosage of CLOPITORVA 20 MG CAPSULE?

The recommended daily dose of CLOPITORVA 20 MG CAPSULE should be taken exactly as directed by your doctor. It is typically taken once a day, and it's advisable to take it with food to avoid stomach upset. Taking it at the same time each day can help maintain a consistent routine.

What are the possible side effects of CLOPITORVA 20 MG CAPSULE?

Common side effects may include headache, dizziness, nausea, diarrhea, stomach pain, indigestion, fatigue, muscle pain or weakness, joint pain, and nosebleeds. Less common side effects can include ankle swelling (oedema) and slow heart rate. If you experience persistent or severe muscle pain, yellowing of the skin, dark urine, or any signs of unusual bleeding, consult your doctor immediately.

Is CLOPITORVA 20 MG CAPSULE safe during pregnancy or breastfeeding?

CLOPITORVA 20 MG CAPSULE is generally not recommended for use during pregnancy as it may cause harm to the developing baby. For breastfeeding mothers, it is advised to consult your doctor, as the medication may pass into breast milk.

Can CLOPITORVA 20 MG CAPSULE be taken with other medications?

This medicine can interact with several other medications. Inform your doctor if you are taking antihypertensive drugs (e.g., Amlodipine), Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), anti-diabetic drugs (e.g., Metformin), certain antibiotics (e.g., Clarithromycin), anti-HIV drugs (e.g., Ritonavir), antifungals (e.g., Itraconazole), other anticoagulants (e.g., Warfarin), Cyclosporine, or some proton pump inhibitors (e.g., Omeprazole). These interactions can increase the risk of side effects like muscle damage or bleeding, or reduce the effectiveness of the medicine.

What precautions should be taken while using CLOPITORVA 20 MG CAPSULE?

It is crucial to inform your doctor about any existing liver disease, kidney disease, bleeding disorders, or diabetes before starting this medication. Avoid consuming alcohol as it may increase the risk of side effects and liver problems. Due to an increased risk of bleeding, be cautious with activities that may cause injury. Do not stop taking the medicine without consulting your doctor, as abrupt discontinuation can increase the risk of cardiovascular events. It is not recommended for children under 18 years of age.

What happens if a dose of CLOPITORVA 20 MG CAPSULE is missed?

If you miss a dose of CLOPITORVA 20 MG CAPSULE, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should CLOPITORVA 20 MG CAPSULE be stored?

CLOPITORVA 20 MG CAPSULE should be stored at room temperature (15-25ºC) in a cool, dry place. Protect it from light and moisture, and keep it out of reach of children. Do not use the medication after the expiry date printed on the packaging.