Triolmezest Ch 40 Tablet

Triolmezest CH 40 Tablet, manufactured by SUN PHARMA LABORATORIES LTD., is a combination medication used for managing hypertension.

Name: Triolmezest CH 40 Tablet

Composition: Each tablet contains Olmesartan Medoxomil 40mg, Amlodipine 5mg, and Chlorthalidone 12.5mg.

Uses: Triolmezest CH 40 Tablet is primarily prescribed for the treatment of hypertension (high blood pressure) to reduce the risk of cardiovascular events such as heart attack and stroke. It also helps manage angina pectoris and reduce fluid accumulation-related swelling in some conditions.

Dosage and Administration: This medicine should be taken orally as directed by a healthcare professional, typically once daily. It can be consumed with or without food, but it is advisable to take it at a fixed time each day. The tablet should be swallowed whole and not chewed, crushed, or broken. To avoid frequent urination disturbing sleep, it is best not to take this medication within four hours of bedtime.

Side Effects: Common side effects may include dizziness, headache, swelling of the ankles or feet, tiredness, nausea, stomach upset, and changes in taste. Serious but rare side effects can include low blood pressure, kidney problems, electrolyte imbalances, and allergic reactions. If any side effects persist or worsen, consult your doctor.

Precautions:

• Avoid use if allergic to any of the ingredients.
• Not recommended for children under 18 years of age.
• Contraindicated during pregnancy and breastfeeding.
• Exercise caution in patients with severe kidney or liver disease; dose adjustment may be necessary.
• May cause dizziness or drowsiness; therefore, caution is advised when driving or operating machinery.
• Alcohol consumption should be avoided as it can increase the risk of low blood pressure.
• Regular monitoring of blood pressure, kidney function, and electrolyte levels is recommended.

Storage: Store in a cool, dry place, away from direct sunlight. Keep out of the reach and sight of children and pets.

What is TRIOLMEZEST CH 40 TABLET used for?

TRIOLMEZEST CH 40 TABLET is primarily used to treat high blood pressure, also known as hypertension, especially when a single medication is not sufficient to control it. This medication helps in reducing the risk of serious cardiovascular events such as heart attacks, strokes, and kidney problems. It may also be used to manage angina pectoris, a type of chest pain caused by reduced blood flow to the heart.

How does TRIOLMEZEST CH 40 TABLET work?

TRIOLMEZEST CH 40 TABLET is a combination medication containing three active ingredients: Olmesartan Medoxomil, Amlodipine, and Chlorthalidone.

• Olmesartan Medoxomil is an angiotensin II receptor blocker (ARB) that works by blocking the action of a hormone called angiotensin II, which normally causes blood vessels to narrow. By blocking this, it relaxes and widens blood vessels, thereby lowering blood pressure.
• Amlodipine is a calcium channel blocker (CCB) that relaxes and widens blood vessels by preventing calcium from entering their muscle cells. This action improves blood flow and oxygen supply to the heart, and reduces blood pressure.
• Chlorthalidone is a diuretic, also known as a "water pill." It increases the excretion of excess water, sodium, and certain other salts from the body through urine. This reduces the fluid volume circulating in the blood vessels, which in turn helps to lower blood pressure.

What is the usual dosage for TRIOLMEZEST CH 40 TABLET?

You should take TRIOLMEZEST CH 40 TABLET exactly as prescribed by your doctor. The usual dose is typically one tablet per day. It is recommended to take it at the same time each day, preferably in the morning. This medicine can be taken with or without food. Do not break, crush, or chew the tablet, and do not alter your dose without consulting your doctor.

What are the possible side effects of TRIOLMEZEST CH 40 TABLET?

Common side effects may include dizziness, headache, stomach upset, nausea, fatigue, and swelling (edema), particularly in the ankles, feet, or legs. You might also experience low blood pressure (hypotension), taste changes, or increased urination due to the diuretic component. Less common side effects can include dehydration, diarrhea, electrolyte imbalance, muscle weakness, dry mouth, and extreme thirst. If any of these side effects become bothersome or persist, you should consult your doctor.

Is TRIOLMEZEST CH 40 TABLET safe during pregnancy or breastfeeding?

Pregnancy: TRIOLMEZEST CH 40 TABLET is generally considered unsafe and is not recommended during pregnancy, especially after the first three months, as it can cause serious harm or even death to the unborn baby. If you become pregnant while taking this medicine, stop immediately and consult your doctor.

Breastfeeding: It is probably unsafe to use TRIOLMEZEST CH 40 TABLET while breastfeeding, as it is unknown whether the medicine passes into breast milk and could harm a nursing infant. You should consult your doctor before using this medication if you are breastfeeding.

Can TRIOLMEZEST CH 40 TABLET be taken with other medications?

It is crucial to inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid potential interactions.

• Avoid or use with caution with:
  • Other blood pressure-lowering medications (e.g., aliskiren, ACE inhibitors like ramipril or lisinopril, ARBs like candesartan) as this can increase the risk of side effects.
  • Potassium supplements or potassium-sparing diuretics (e.g., amiloride, spironolactone), as they can lead to dangerously high potassium levels in the blood.
  • Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) such as aspirin, ibuprofen, or naproxen, which may reduce the effectiveness of TRIOLMEZEST CH 40 TABLET and increase the risk of kidney damage.
  • Lithium, as it can increase lithium levels in your blood, potentially leading to toxicity.
  • Grapefruit juice and grapefruit, which can cause a significant drop in blood pressure.
  • Alcohol, as it can enhance the blood pressure-lowering effect of the medicine, leading to increased dizziness or fainting.

What precautions should be taken while using TRIOLMEZEST CH 40 TABLET?

Before starting this medication, inform your doctor if you have a history of kidney disease, liver disease, diabetes, heart conditions (such as stenosis or heart failure), very low blood pressure, dehydration, electrolyte imbalances, or problems with your adrenal glands.

• Avoid driving or operating heavy machinery if you experience dizziness, fatigue, or headaches after taking the medication.
• Do not stop taking this medicine suddenly without consulting your doctor, as this can lead to a dangerous rise in blood pressure and serious health complications.
• Regular monitoring of blood pressure, kidney function, electrolyte levels, and blood sugar is recommended to ensure the medicine is working effectively and safely.
• Stay well-hydrated, especially due to the diuretic effect, but avoid excessive salt intake.
• This medicine is not recommended for children under 18 years of age.

What happens if a dose of TRIOLMEZEST CH 40 TABLET is missed?

If you miss a dose of TRIOLMEZEST CH 40 TABLET, take it as soon as you remember, provided there is enough time before your next scheduled dose. If it is almost time for your next dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this can increase the risk of side effects. Missing a dose can lead to a temporary rise in blood pressure, so consistent use is important.

How should TRIOLMEZEST CH 40 TABLET be stored?

Store TRIOLMEZEST CH 40 TABLET in a cool, dry place, away from direct sunlight and moisture. Keep it out of the reach and sight of children and pets. The medicine should be stored at room temperature, typically between 15-25°C. Any unused or expired medicine should be disposed of properly according to local guidelines.