Voage M 10 Mg/1000 Mg Tablet (10 Tab)

VOAGE M 10 MG/1000 MG TABLET by Alembic Pharmaceuticals Limited

Name

Brand Name: VOAGE M 10/1000 MG TABLET

Composition

VOAGE M 10/1000 MG TABLET is a fixed-dose combination medication containing two active ingredients:

• Dapagliflozin: 10 mg
• Metformin Hydrochloride: 1000 mg

Uses

VOAGE M 10/1000 MG TABLET is prescribed for the management of type 2 diabetes mellitus in adults, alongside diet and exercise, especially when blood sugar cannot be adequately controlled with other medicines alone. It helps to control high blood sugar levels, which reduces the chances of serious complications of diabetes such as kidney damage, blindness, and nerve damage, and may also help prevent heart disease. Dapagliflozin works by removing excess sugar from the body through urine by blocking the SGLT-2 enzyme, while Metformin decreases glucose production in the liver and improves the body's sensitivity to insulin.

Dosage and Administration

This medicine should be taken orally as advised by your physician, usually with food, to minimize stomach upset. Swallow the tablet whole with a glass of water; do not crush or chew it. Your doctor will determine the correct dose and duration based on your age, body weight, and medical condition. It is important to take the medicine at the same time every day to maintain consistent blood sugar levels and not to stop taking it without consulting your doctor.

Side Effects

Common side effects include:

• Diarrhea, stomach pain, nausea, and vomiting
• Urinary tract infections (UTIs) and frequent urination
• Female genital mycotic infections (yeast infections)
• Headache
• Loss of appetite

Serious side effects, though rare, can include:

• Lactic acidosis
• Ketoacidosis
• Dehydration (symptoms like dizziness, dry mouth, or low blood pressure)
• Severe allergic reactions

Precautions

• Contraindications: VOAGE M 10/1000 MG TABLET is not recommended for patients with type 1 diabetes mellitus, diabetic ketoacidosis, severe kidney disease, liver disease, recent heart attack, heart failure, or severe infection.
• Alcohol: Avoid excessive alcohol consumption as it can increase the risk of lactic acidosis and low blood sugar.
• Pregnancy and Breastfeeding: It is generally not recommended during the second and third trimesters of pregnancy and while breastfeeding, as it may pass into breast milk. Consult your doctor for alternative options.
• Kidney and Liver Impairment: Use with caution in patients with existing kidney or liver problems. Regular blood tests may be required to monitor kidney function.
• Hydration: Drink plenty of fluids to prevent dehydration, especially during hot weather or intense exercise.
• Hypoglycemia: While the risk is lower than with some other diabetes medications, it can cause low blood sugar, especially when used with other antidiabetic medicines or if meals are delayed. Always carry sugary food or fruit juice.
• Allergies: Inform your doctor about any known allergies to dapagliflozin or metformin.
• Children and Elderly: Not recommended for use in children and adolescents under 18 years of age. Use with caution in elderly patients (65 years or above).

Storage

Store in a cool and dry place, away from direct sunlight. Keep out of sight and reach of children. Store below 30°C (10ºC to 25ºC).

VOAGE M 10 MG/1000 MG TABLET is a medication primarily used for the management of type 2 diabetes mellitus in adults. It combines two active ingredients, Dapagliflozin and Metformin, to help control blood sugar levels.

What is VOAGE M 10 MG/1000 MG TABLET used for?

VOAGE M 10 MG/1000 MG TABLET is used to treat type 2 diabetes mellitus in adults. It helps control high blood sugar levels, especially when diet and exercise alone or other single-drug therapies are not sufficient. This medication can also help reduce the risk of serious complications associated with diabetes, such as kidney damage, blindness, and nerve damage.

How does VOAGE M 10 MG/1000 MG TABLET work?

This tablet contains two active ingredients: Dapagliflozin and Metformin. Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor that works by causing the kidneys to remove excess glucose from the body through urine. Metformin, a biguanide, works by decreasing glucose production in the liver, reducing glucose absorption from the intestines, and improving the body's sensitivity to insulin. Together, these actions help to lower blood sugar levels effectively.

What is the usual dosage of VOAGE M 10 MG/1000 MG TABLET?

The dosage of VOAGE M 10 MG/1000 MG TABLET is determined by your doctor based on your individual condition and response to the medicine. It is typically taken orally, usually once daily with food. It is crucial to follow your doctor's prescribed dose and not to change it without consultation.

What are the possible side effects of VOAGE M 10 MG/1000 MG TABLET?

Common side effects may include frequent urination, female genital mycotic infections (yeast infections), urinary tract infections, diarrhea, nausea, vomiting, headache, and abdominal pain. Most of these side effects are usually temporary and resolve over time. However, if any of these persist or worsen, you should consult your doctor. Serious but rare side effects like lactic acidosis and ketoacidosis can also occur.

Is VOAGE M 10 MG/1000 MG TABLET safe during pregnancy or breastfeeding?

VOAGE M 10 MG/1000 MG TABLET is generally not recommended during pregnancy, especially in the second and third trimesters, as it may be unsafe and could potentially harm the fetus. It is also considered unsafe during breastfeeding as the drug may pass into breast milk. Always consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Can VOAGE M 10 MG/1000 MG TABLET be taken with other medications?

VOAGE M 10 MG/1000 MG TABLET can interact with certain other medications. It's important to inform your doctor about all medicines, supplements, or herbal products you are currently taking. Interactions can occur with diuretics (water pills), carbonic anhydrase inhibitors, certain medications that reduce metformin clearance (like ranolazine, vandetanib, dolutegravir, cimetidine), insulin, and insulin secretagogues (e.g., sulfonylureas), which may increase the risk of low blood sugar.

What precautions should be taken while using VOAGE M 10 MG/1000 MG TABLET?

Avoid alcohol consumption while taking this medication, as it can increase the risk of lactic acidosis. Inform your doctor if you have kidney or liver disease, heart conditions, a history of dehydration, or frequently get urinary tract infections. This medicine is not recommended for type 1 diabetes or diabetic ketoacidosis. It should be used with caution in elderly patients.

What happens if a dose of VOAGE M 10 MG/1000 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should VOAGE M 10 MG/1000 MG TABLET be stored?

Store VOAGE M 10 MG/1000 MG TABLET at room temperature, ideally below 25-30°C. Keep it in its original packaging to protect it from moisture, light, and heat. Ensure it is kept out of the sight and reach of children.