Dapanova-m 10/500 Tablet

DAPANOVA-M 10/500 TABLET

DAPANOVA-M 10/500 Tablet is a medication manufactured by Medley Pharmaceuticals Ltd., primarily used in the management of Type 2 Diabetes Mellitus.

• Name: Dapanova M 10/500 Tablet

• Composition: Each tablet contains:

  • Dapagliflozin: 10 mg
  • Metformin: 500 mg

• Uses:

  • Management of Type 2 Diabetes Mellitus in adults, particularly when diet and exercise alone are insufficient for blood sugar control.
  • Helps lower blood glucose levels by increasing glucose excretion through urine and improving insulin sensitivity.
  • Can reduce the risk of hospitalization due to heart failure in adults with Type 2 Diabetes and established cardiovascular disease or multiple cardiovascular risk factors.
  • Also plays a role in preventing heart disease and reducing serious diabetes-related complications like kidney damage and blindness.

• Dosage and Administration:

  • Typically taken orally as directed by a doctor.
  • Usually taken once daily, with or without food.
  • It is crucial to consult a doctor for the exact dosage and timing, and to take the medicine at the same time every day for optimal effectiveness.
  • The medication is intended for use only by adults aged 18 years and older.

• Side Effects:

  • Common: Sore throat, stuffy or runny nose, headache, nausea, vomiting, diarrhea, frequent urination, mild skin rash or itchy skin, abdominal pain, genital fungal infections, and urinary tract infections.
  • Serious: Hypoglycemia (low blood sugar), especially when combined with insulin or other blood sugar-lowering medications. Lactic acidosis (rare but serious complication) may occur.

• Precautions:

  • Allergies: Avoid use if allergic to dapagliflozin, metformin, or any other ingredient.
  • Medical Conditions: Inform your doctor about kidney or liver problems, urinary tract infections, heart conditions, or a history of diabetic ketoacidosis.
  • Dehydration: Stay well-hydrated to prevent dehydration.
  • Alcohol: Avoid excessive alcohol consumption as it may increase the risk of lactic acidosis.
  • Pregnancy and Breastfeeding: Not recommended during pregnancy and breastfeeding; consult a doctor for alternative options.
  • Drug Interactions: May interact with diuretics (e.g., furosemide), insulin and insulin secretagogues (e.g., glipizide) increasing the risk of hypotension, electrolyte imbalances, and hypoglycemia. Carbonic anhydrase inhibitors (e.g., acetazolamide) may increase the risk of lactic acidosis.
  • Regular monitoring of blood sugar levels is essential.

• Storage:

  • Store in a cool and dry place away from sunlight.
  • Keep out of sight and reach of children.
  • Typically stored at room temperature, below 30°C.

DAPANOVA-M 10/500 Tablet, manufactured by Medley Pharmaceuticals Ltd., is a combination medication primarily used for the management of Type 2 Diabetes Mellitus. It contains Dapagliflozin and Metformin, which work together to help control blood sugar levels.

What is DAPANOVA-M 10/500 Tablet used for?

DAPANOVA-M 10/500 Tablet is used to treat Type 2 Diabetes Mellitus in adults, especially when diet and exercise alone are insufficient to control blood sugar levels. It also helps reduce the risk of hospitalization for heart failure in adults with Type 2 diabetes who have established cardiovascular disease or multiple cardiovascular risk factors.

How does DAPANOVA-M 10/500 Tablet work?

This medicine combines two active ingredients: Dapagliflozin and Metformin. Dapagliflozin is an SGLT2 inhibitor that works by blocking the reabsorption of glucose in the kidneys, leading to increased glucose excretion through urine. Metformin, a biguanide, reduces glucose production in the liver, delays glucose absorption from the intestines, and improves the body's sensitivity to insulin.

What is the usual dosage for DAPANOVA-M 10/500 Tablet?

The usual dosage is typically once daily, often in the morning, or as directed by your doctor. It can be taken with or without food. Your doctor will determine the correct dose and duration based on your medical condition and response to treatment. It's important to take it at the same time each day to help remember.

What are the possible side effects of DAPANOVA-M 10/500 Tablet?

Common side effects can include frequent urination, mild skin rash or itchy skin, diarrhea, stomach ache, nausea, vomiting, headache, dizziness, genital mycotic infections (fungal infections in the genital area), and urinary tract infections. Less common but serious side effects can include dehydration and, rarely, lactic acidosis. If you experience persistent side effects or symptoms like extreme weakness, tremors, confusion, difficulty breathing, or stomach pain, contact your doctor immediately.

Is DAPANOVA-M 10/500 Tablet safe during pregnancy or breastfeeding?

DAPANOVA-M 10/500 Tablet is generally not recommended during pregnancy, especially during the second and third trimesters, due to insufficient safety data and potential risks to the unborn baby. It is also not advised during breastfeeding as it may pass into breast milk and affect infant kidney development. Always consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Can DAPANOVA-M 10/500 Tablet be taken with other medications?

It's crucial to inform your doctor about all medications, supplements, and herbal products you are taking. DAPANOVA-M 10/500 Tablet may interact with diuretics (like furosemide), insulin and insulin secretagogues (like glipizide), carbonic anhydrase inhibitors (like acetazolamide), and certain cationic medicines (like amiloride, digoxin). Concurrent use with insulin or insulin secretagogues may increase the risk of hypoglycemia. Your doctor may adjust dosages if taken with other antidiabetic medicines.

What precautions should be taken while using DAPANOVA-M 10/500 Tablet?

DAPANOVA-M 10/500 Tablet should not be used if you have Type 1 diabetes, severe kidney or liver disease, diabetic ketoacidosis, a recent heart attack, or severe infection. Caution is advised with alcohol consumption as it may increase the risk of lactic acidosis. Maintain good hygiene to prevent genital fungal infections and drink plenty of fluids to avoid dehydration. Regular monitoring of blood sugar levels is essential.

What happens if a dose of DAPANOVA-M 10/500 Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should DAPANOVA-M 10/500 Tablet be stored?

DAPANOVA-M 10/500 Tablet should be stored in a cool and dry place, away from direct sunlight. Keep it out of sight and reach of children. The recommended storage temperature is typically between 10ºC to 25ºC or below 30ºC.