Pari Cr Plus Tab

PARI CR PLUS TAB by IPCA LABORATORIES LTD

PARI CR PLUS is a fixed-dose combination medication manufactured by IPCA LABORATORIES LTD. It is an allopathic medicine primarily used to manage various mood and anxiety disorders.

• Composition Each tablet contains Paroxetine 12.50 mg and Clonazepam 0.50 mg. Paroxetine is a selective serotonin reuptake inhibitor (SSRI) that increases serotonin levels in the brain to improve mood. Clonazepam is a benzodiazepine that enhances the effects of GABA, a calming chemical in the brain, reducing abnormal nerve activity.

• Uses PARI CR PLUS is prescribed for the treatment of:

  • Depression
  • Anxiety disorders
  • Panic disorders
  • Obsessive-compulsive disorder (OCD)
  • Post-traumatic stress disorder (PTSD)
  • Certain types of phobias (fears)

• Dosage and Administration Take PARI CR PLUS orally with water, precisely as directed by a healthcare professional. It can be taken with or without food, though some sources suggest preferably with or after meals. Do not crush or chew the tablet. It is crucial to follow the prescribed dosage and duration and not to stop the medication abruptly, as this may lead to withdrawal symptoms.

• Side Effects Common side effects may include headache, nausea, constipation, insomnia, dizziness, drowsiness, tiredness, dry mouth, increased sweating, decreased sexual desire, erectile dysfunction, and weight gain. Serious side effects requiring immediate medical attention include worsening depression with suicidal thoughts, or symptoms of Serotonin Syndrome or Neuroleptic Malignant Syndrome (e.g., severe muscle stiffness, shakiness, fever, chest pain).

• Precautions

  • Pregnancy and Breastfeeding: Not generally recommended during pregnancy or breastfeeding due to potential risks to the fetus or infant.
  • Alcohol: Avoid alcohol consumption as it can intensify side effects like drowsiness.
  • Driving and Operating Machinery: Avoid activities requiring high mental alertness if experiencing dizziness, drowsiness, or blurred vision.
  • Drug Interactions: Inform your doctor about all medications, supplements, and herbal products. This medicine is contraindicated with Monoamine Oxidase Inhibitors (MAOIs), Pimozide, and Thioridazine.
  • Medical Conditions: Use with caution in patients with liver, kidney, or heart disease, diabetes, glaucoma, breathing problems, bleeding disorders, or a history of seizures or psychiatric conditions.

• Storage Store PARI CR PLUS TABLET at room temperature (20-25°C), protected from moisture and light. Keep out of reach of children and pets.

PARI CR PLUS Tablet is a combination medicine containing Clonazepam (an anticonvulsant/benzodiazepine) and Paroxetine (an antidepressant/SSRI). It is primarily used to manage various mental health conditions.

What is PARI CR PLUS Tablet used for?

PARI CR PLUS Tablet is used to manage depression and anxiety. It is also prescribed for conditions such as panic attacks, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), generalized anxiety disorder, and certain phobias.

How does PARI CR PLUS Tablet work?

This medicine works due to its two active ingredients. Paroxetine, a selective serotonin reuptake inhibitor (SSRI), increases the levels of serotonin in the brain, which helps to improve mood and emotions. Clonazepam, a benzodiazepine, works by enhancing the action of gamma-aminobutyric acid (GABA), a calming chemical in the brain, which suppresses abnormal electrical activity and reduces anxiety.

What is the usual dosage for PARI CR PLUS Tablet?

The dosage of PARI CR PLUS Tablet should be taken exactly as advised by your physician. It is usually taken once daily, preferably with or after meals, at a fixed time each day. Your doctor will determine the correct dose and duration based on your age, body weight, and medical condition. Do not stop taking this medicine abruptly without consulting your doctor, as it can lead to withdrawal symptoms.

What are the possible side effects of PARI CR PLUS Tablet?

Common side effects include headache, dizziness, tiredness, sleepiness, tremor, nausea, constipation, diarrhea, dry mouth, increased sweating, lack of sleep, high blood cholesterol levels, erectile dysfunction, and weight gain. More serious side effects, though rare, can include suicidal thoughts and behaviors, restlessness, increased irritation, or signs of serotonin syndrome (agitation, hallucinations, rapid heartbeat, fever, stiff muscles). Consult your doctor if any side effects worsen or if you experience severe symptoms.

Is PARI CR PLUS Tablet safe during pregnancy or breastfeeding?

PARI CR PLUS Tablet is generally not recommended and is considered unsafe for use during pregnancy, as it may harm the developing baby. It is also not recommended for use by breastfeeding women as it may pass into breast milk and affect the nursing infant. Always consult your doctor before taking this medicine if you are pregnant, planning to conceive, or breastfeeding.

Can PARI CR PLUS Tablet be taken with other medications?

Before taking PARI CR PLUS Tablet, inform your doctor about all other medications, supplements, and herbal products you are currently taking. It should not be taken with monoamine oxidase inhibitors (MAOIs). Alcohol should be avoided as it can increase drowsiness and other side effects. Grapefruit juice may also interact with this medicine. Caution is advised with other medications, including blood thinners like warfarin and NSAIDs like aspirin.

What precautions should be taken while taking PARI CR PLUS Tablet?

Exercise caution if you have a history of liver, kidney, or heart disease, diabetes, glaucoma, breathing problems, bleeding disorders, mania, or a history of drug or alcohol abuse. This medicine can cause drowsiness, dizziness, and blurred vision, so avoid driving or operating heavy machinery until you know how it affects you. There is an increased risk of suicidal thoughts, especially at the beginning of treatment, so monitor for changes in mood or behavior and report them to your doctor. It is not recommended for use in children and adolescents under 18 years of age.

What happens if a dose of PARI CR PLUS Tablet is missed?

If you miss a dose of PARI CR PLUS Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this could lead to toxicity.

How should PARI CR PLUS Tablet be stored?

PARI CR PLUS Tablet should be stored at room temperature (20-25°C), away from direct sunlight, excess heat, and moisture. Keep it in its original packet or container, tightly closed, and out of reach of children and pets.